中华神经医学杂志
中華神經醫學雜誌
중화신경의학잡지
CHINESE JOURNAL OF NEUROMEDICINE
2014年
12期
1203-1206
,共4页
文丽红%陈静贤%白一辰%姚陇平%张世忠
文麗紅%陳靜賢%白一辰%姚隴平%張世忠
문려홍%진정현%백일신%요롱평%장세충
丘脑底核%红核%靶点定位%帕金森病%脑深部电刺激术
丘腦底覈%紅覈%靶點定位%帕金森病%腦深部電刺激術
구뇌저핵%홍핵%파점정위%파금삼병%뇌심부전자격술
Subthalamic nucleus%Red nucleus%Target localization%Parkinson's disease%Subthalamic nucleus-deep brain stimulation
目的 探讨脑深部电刺激术(STN-DBS)中以红核中心为标定点的丘脑底核靶点定位的方法. 方法 选择南方医科大学珠江医院神经外科自2012年9月至2013年9月收集的16例成年人志愿者为研究对象,其中帕金森病(PD)患者8例(PD组),正常人8例(正常人组).于红核直径最大的图层上,取国际公认12mm线,及其所确定的靶点与红核中点的连线,和前后联合连线所围成的三角形,测量其较大锐角(记为角度α)和边长(记为长度b).采用SPSS13.0软件进行数据处理和分析. 结果 16例志愿者的红核直径a左侧为(0.93±0.05) cm,右侧为(0.92±0.03) cm;长度b左侧为(0.81±0.09) cm,右侧为(0.82±0.06) cm;角度α左侧为(56.76±2.87)°,右侧为(55.98±2.30)°.PD组左、右侧红核直径a、长度b以及角度α与正常人组之间的差异无统计学意义(P＞0.05). 结论 以红核中心为标定点的丘脑底核靶点定位方法具有较高的临床应用价值,可作为辅助方法提高手术靶点定位的准确度.
目的 探討腦深部電刺激術(STN-DBS)中以紅覈中心為標定點的丘腦底覈靶點定位的方法. 方法 選擇南方醫科大學珠江醫院神經外科自2012年9月至2013年9月收集的16例成年人誌願者為研究對象,其中帕金森病(PD)患者8例(PD組),正常人8例(正常人組).于紅覈直徑最大的圖層上,取國際公認12mm線,及其所確定的靶點與紅覈中點的連線,和前後聯閤連線所圍成的三角形,測量其較大銳角(記為角度α)和邊長(記為長度b).採用SPSS13.0軟件進行數據處理和分析. 結果 16例誌願者的紅覈直徑a左側為(0.93±0.05) cm,右側為(0.92±0.03) cm;長度b左側為(0.81±0.09) cm,右側為(0.82±0.06) cm;角度α左側為(56.76±2.87)°,右側為(55.98±2.30)°.PD組左、右側紅覈直徑a、長度b以及角度α與正常人組之間的差異無統計學意義(P＞0.05). 結論 以紅覈中心為標定點的丘腦底覈靶點定位方法具有較高的臨床應用價值,可作為輔助方法提高手術靶點定位的準確度.
목적 탐토뇌심부전자격술(STN-DBS)중이홍핵중심위표정점적구뇌저핵파점정위적방법. 방법 선택남방의과대학주강의원신경외과자2012년9월지2013년9월수집적16례성년인지원자위연구대상,기중파금삼병(PD)환자8례(PD조),정상인8례(정상인조).우홍핵직경최대적도층상,취국제공인12mm선,급기소학정적파점여홍핵중점적련선,화전후연합련선소위성적삼각형,측량기교대예각(기위각도α)화변장(기위장도b).채용SPSS13.0연건진행수거처리화분석. 결과 16례지원자적홍핵직경a좌측위(0.93±0.05) cm,우측위(0.92±0.03) cm;장도b좌측위(0.81±0.09) cm,우측위(0.82±0.06) cm;각도α좌측위(56.76±2.87)°,우측위(55.98±2.30)°.PD조좌、우측홍핵직경a、장도b이급각도α여정상인조지간적차이무통계학의의(P＞0.05). 결론 이홍핵중심위표정점적구뇌저핵파점정위방법구유교고적림상응용개치,가작위보조방법제고수술파점정위적준학도.
Objective To investigate an approach for locating the operation target of deep brain stimulation (DBS) (subthalamic nucleus,STN) based on the center of the red nucleus (RN).Methods Sixteen adults,including 8 with Parkinson' s disease (PD) and 8 from healthy volunteers,collected in our hospital from September 2012 to September 2013,were chosen; transverse T2-weighted MRI (3.0T) was performed.On the layer of the RN's maximum diameter,a right triangle was formed by three lines:the first one (marked as line AB) was the acknowledged 12 mm line,the second one (marked as line AC) was connected by the operation target and the RN center,and the third one (marked as line BC) was connected by the anterior commissure (AC) and posterior commissure (PC).The angle (marked as α) formed by the AC-PC plane and line AC and the length of the line BC (marked as b) were measured and analyzed.Results The average length of the RN diameter in 16 adults was (0.93±0.05) cm in the left cerebral hemisphere and (0.92±0.03) cm in the right.The length of line b was (0.81 ±0.09) cm in the left and (0.82±0.06) cm in the right.The angle α was (56.76±2.87)° in the left and (55.98±2.30)° in the right.The RN diameter,length of line b and angle α in patients from PD group showed no significant differences as compared with those in the normal controls (P＞0.05).Conclusion The RN center can be used for indirectly locating STN before DBS for PD treatment.
