CAJ | 학술논문

目的观察LASIK术后人群在低压缺氧环境中视功能变化情况,了解准分子激光角膜屈光手术眼在飞行特殊环境的适应性.方法自身前后对照研究.20名(40眼)健康志愿者,平均年龄为(23.8±1.2)岁,准分子激光近视矫正术后1年.低压舱上升前测量眼压、近立体视、色觉、屈光度、对比敏感度(双眼明视、暗视眩光下空间频率3、6、12、18c/d的对比敏感度值),低压舱以30 m/s速度上升至5000 m高度,在此高度停留10 min后再次测量,此过程无供氧,测量后低压舱以10～15 m/s速度下降至地面.对相应数据采用配对t检验进行分析.结果低压舱实验前后眼压未见明显变化[(右眼(13.0±1.7)mmHgvs.(13.0±2.1)mmHg,t=-0.56,P＞0.05;左眼(13.0±2.0 mmHg vs.(13.0±2.0) mmHg,t=-0.81,P＞0.05)];近立体视[(21.5±2.4)弧秒vs.(27.6±8.3)弧秒,t=-3.39,P＜0.05)及色觉(9.60±2.73vs.27.20±8.57,=-2.81,P＜0.05)]下降;等效球镜度[(右眼(-0.90±0.61)Dvs.(-1.08±0.75)D,t=1.71,P＞0.05,左眼(-1.21±0.61)Dvs.(-1.06±0.54)D,t=-1.33,P＞0.05)差异无统计学意义;对比敏感度(18 c/d暗视眩光环境对比敏感度降低P＜0.05,其他情况均未见降低).结论低压缺氧环境对准分子激光术后远期人群的眼压、屈光度、对比敏感度(除高频暗视眩光)均无影响;近立体视、色觉及高频暗视眩光条件的对比敏感度下降.
목적 관찰LASIK술후인군재저압결양배경중시공능변화정황,료해준분자격광각막굴광수술안재비행특수배경적괄응성.방법 자신전후대조연구.20명(40안)건강지원자,평균년령위(23.8±1.2)세,준분자격광근시교정술후1년.저압창상승전측량안압、근입체시、색각、굴광도、대비민감도(쌍안명시、암시현광하공간빈솔3、6、12、18c/d적대비민감도치),저압창이30 m/s속도상승지5000 m고도,재차고도정류10 min후재차측량,차과정무공양,측량후저압창이10～15 m/s속도하강지지면.대상응수거채용배대t검험진행분석.결과 저압창실험전후안압미견명현변화[(우안(13.0±1.7)mmHgvs.(13.0±2.1)mmHg,t=-0.56,P＞0.05;좌안(13.0±2.0 mmHg vs.(13.0±2.0) mmHg,t=-0.81,P＞0.05)];근입체시[(21.5±2.4)호초vs.(27.6±8.3)호초,t=-3.39,P＜0.05)급색각(9.60±2.73vs.27.20±8.57,=-2.81,P＜0.05)]하강;등효구경도[(우안(-0.90±0.61)Dvs.(-1.08±0.75)D,t=1.71,P＞0.05,좌안(-1.21±0.61)Dvs.(-1.06±0.54)D,t=-1.33,P＞0.05)차이무통계학의의;대비민감도(18 c/d암시현광배경대비민감도강저P＜0.05,기타정황균미견강저).결론 저압결양배경대준분자격광술후원기인군적안압、굴광도、대비민감도(제고빈암시현광)균무영향;근입체시、색각급고빈암시현광조건적대비민감도하강.
Objective To test the effects of altitude hypoxia on visual function after laser in situ keratomileusis (LASIK) and to evaluate flight adaptability after laser refractive surgery.Methods This was a self-control designed study.Forth eyes of 20 healthy males with a mean age of 23.8±1.2 years volunteered for this prospective study.All patients had bilateral LASIK surgery 1 year prior to the study.Interocular pressure,near stereopsis,color vision,refractive error,contrast sensitivity (CS) (photopic,scotopic+glare environments; 3,6,12,18 c/d spatial frequencies) were measured before exposure to the hypobaric chamber.The atmosphere in the chamber ascended to an equivalent of a 5 000 m altitude at the rate of 30 m/s.Subjects were measured again after remaining there for 10 minutes without an oxygen supply.The chamber then returned to ground level at the rate of 10-15 m/s.Data were analyzed using a paired t test.Results There were no significant differences in intraocular pressure or spherical equivalent refractive error for either eye before and after the hypobaric experiment:right eyes:13.0±1.7 mmHg vs.13.0±2.1 mmHg,t=-0.56,P＞0.05,-0.90±0.61 D vs.-1.08±0.75 D,t=1.71,P＞0.05; left eyes:13.0±2.0 mmHg vs.13.0±2.0 mmHg,t=-0.81,P＞0.05;-1.21±0.61 D vs.-1.06±0.54 D,t=-1.33,P＞0.05).Near stereopsis (21.5±2.4 vs.27.6±8.3,t=-3.39,P＜0.05) and color vision (9.60±2.73 vs.27.20±8.57,t=-2.81,P＜0.05) were depressed.Contrast sensitivity was depressed only at 18 cycles/degree in the scotopic+glare environment.Conclusion Based on this study,we conclude that hypoxia has little effect on interocular pressure,refractive error or CS except at 18 c/d in the scotopic+glare environment after LASIK surgery.Near stereopsis,color vision and CS at 18 c/d in the scotopic+glare environment were reduced.