CAJ | 학술논문

目的观察连续性血液净化(CBP)对重症肺外型急性呼吸窘迫综合征(ARDSexp)患者肺血管外肺水及通透指数的影响.方法 15例确诊的重症ARDSexp患者行CBP治疗,记录治疗开始后反映肺血管外肺水的指标血管外肺水指数(EVLWI)、肺毛细血管通透指数(PVH)及炎性指标水平的变化.结果与治疗前比较,治疗后EVLWI、PVH有明显下降(P＜0.01),C反应蛋白、白细胞介素-6、降钙素原、系统性炎症反应综合征评分及急性生理和慢性健康状况Ⅱ评分有明显下降(P＜0.01).结论 CBP可改善重症ARDSexp患者肺血管外肺水及通透指数和全身炎性反应水平及预后.
목적 관찰련속성혈액정화(CBP)대중증폐외형급성호흡군박종합정(ARDSexp)환자폐혈관외폐수급통투지수적영향.방법 15례학진적중증ARDSexp환자행CBP치료,기록치료개시후반영폐혈관외폐수적지표혈관외폐수지수(EVLWI)、폐모세혈관통투지수(PVH)급염성지표수평적변화.결과 여치료전비교,치료후EVLWI、PVH유명현하강(P＜0.01),C반응단백、백세포개소-6、강개소원、계통성염증반응종합정평분급급성생리화만성건강상황Ⅱ평분유명현하강(P＜0.01).결론 CBP가개선중증ARDSexp환자폐혈관외폐수급통투지수화전신염성반응수평급예후.
Objective To observe the effects of continuous blood purification(CBP) on extravascular lung water and permeability index in patients with severe extrapulmonary acute respiratory distress syndrome (ARDSexp).Methods Fifteen patients with severe ARDSexp were treated with CBP.The level of extravascular lung water index (EVLWI) and pulmonary vascular permeability index (PVPI) was measured before and after treatment,and at the same time the changes of inflammatory indicators were recorded.Results Compared with that before treatment,EVLWI and PVPI was decreased obviously after treatment (P ＜ 0.01),the level of C-reactive protein and interleukin 6 (IL-6),calcitonin and systemic inflammatory response syndrome score and the acute physiology and chronic health Ⅱ score was significantly decreased (P ＜ 0.01).Conclusion CBP can improve the level of EVLWI,PVPI and inflammatory indicators and also the prognosis of severe ARDSexp.