中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
22期
60-63
,共4页
汪飞%廖庆红%秦丽丽%陈诗莉%徐文文%周志明
汪飛%廖慶紅%秦麗麗%陳詩莉%徐文文%週誌明
왕비%료경홍%진려려%진시리%서문문%주지명
卒中%二级预防%羟甲基戊二酰基CoA还原酶抑制剂%病人依从
卒中%二級預防%羥甲基戊二酰基CoA還原酶抑製劑%病人依從
졸중%이급예방%간갑기무이선기CoA환원매억제제%병인의종
Stroke%Secondary prevention%Hydroxymethylglutaryl-CoA reductase inhibitors%Patient compliance
目的 观察缺血性卒中二级预防中他汀类药物的应用现状,分析影响其依从性的因素.方法 选取2011年12月至2012年10月连续入院的缺血性卒中患者,收集其临床特征及可能影响他汀类药物依从性的因素,随访发病后3个月时的应用情况,采用多元Logistic回归进行统计学分析.结果 368例患者住院期间有67.9％(250/368)的患者应用他汀类药物.他汀类药物在高危、极高危Ⅱ及极高危Ⅰ的指南符合率分别为28.1％(18/64)、44.1％(30/68)和72.3％(136/188), 多元Logistic回归分析发现住院期间使用他汀类药物与颈动脉易损斑块(OR=5.308,P=0.000)及糖尿病病史相关(OR=1.789,P=0.032).3个月时他汀类药物总体应用率为22.6％(82/363),出院医嘱规范者用药依从性高.结论 他汀类药物应用与指南存在差距,标准出院医嘱能够提高用药的依从性.
目的 觀察缺血性卒中二級預防中他汀類藥物的應用現狀,分析影響其依從性的因素.方法 選取2011年12月至2012年10月連續入院的缺血性卒中患者,收集其臨床特徵及可能影響他汀類藥物依從性的因素,隨訪髮病後3箇月時的應用情況,採用多元Logistic迴歸進行統計學分析.結果 368例患者住院期間有67.9％(250/368)的患者應用他汀類藥物.他汀類藥物在高危、極高危Ⅱ及極高危Ⅰ的指南符閤率分彆為28.1％(18/64)、44.1％(30/68)和72.3％(136/188), 多元Logistic迴歸分析髮現住院期間使用他汀類藥物與頸動脈易損斑塊(OR=5.308,P=0.000)及糖尿病病史相關(OR=1.789,P=0.032).3箇月時他汀類藥物總體應用率為22.6％(82/363),齣院醫囑規範者用藥依從性高.結論 他汀類藥物應用與指南存在差距,標準齣院醫囑能夠提高用藥的依從性.
목적 관찰결혈성졸중이급예방중타정류약물적응용현상,분석영향기의종성적인소.방법 선취2011년12월지2012년10월련속입원적결혈성졸중환자,수집기림상특정급가능영향타정류약물의종성적인소,수방발병후3개월시적응용정황,채용다원Logistic회귀진행통계학분석.결과 368례환자주원기간유67.9％(250/368)적환자응용타정류약물.타정류약물재고위、겁고위Ⅱ급겁고위Ⅰ적지남부합솔분별위28.1％(18/64)、44.1％(30/68)화72.3％(136/188), 다원Logistic회귀분석발현주원기간사용타정류약물여경동맥역손반괴(OR=5.308,P=0.000)급당뇨병병사상관(OR=1.789,P=0.032).3개월시타정류약물총체응용솔위22.6％(82/363),출원의촉규범자용약의종성고.결론 타정류약물응용여지남존재차거,표준출원의촉능구제고용약적의종성.
Objective To investigate the application of statins in secondary prevention of ischemic stroke in different risk groups,and to identify the factors influencing the comphcance of statins.Me.ods Ischemic stroke patients from December 2011 to October 2012 were collected.All clinical characterisitcs and possible factors influencing the compliance of statins was recorded in 3 months.The multivariate Logistic regression analysis was used to analyze the influencing factors of the compliance of statins.Results All 368 patients were collected,and 67.9％(250/368) patients were prescribed statins for therapy during hospitalization.The application rate of statins in accordance with guidelines in high-risk,extremely high-risk Ⅱ and extremely high-risk Ⅰ patients was 28.1％ (18/64),44.1％ (30/68) and 72.3％ (136/188),respectively.Logistic regression analysis showed that the statins application during hospitalization was associated with the presence of carotid vulnerable plaques (OR =5.308,P =0.000) and diabetes history (OR =1.789,P =0.032).Routine discharge instructions had high compliance.Conclusion The compliance of statins in secondary prevention of ischemic stroke still has a large gap between clinical practice and guidelines,and routine discharge instructions on statins application increase the compliance of statins.
