中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
31期
39-41
,共3页
肝硬化%糖尿病,2型%维生素D%肝源性糖尿病%Child-Pugh分级
肝硬化%糖尿病,2型%維生素D%肝源性糖尿病%Child-Pugh分級
간경화%당뇨병,2형%유생소D%간원성당뇨병%Child-Pugh분급
Liver cirrhosis%Diabetes mellitus,type 2%Vitamin D%Hepatic diabetes%Child-Pugh classification
目的 探讨维生素D水平与肝硬化分级相关性.方法 收集肝源性糖尿病患者38例,2型糖尿病患者48例,健康对照者30例,监测血清25-(OH) D3水平,并计算Child-Pugh积分,分析肝源性糖尿病发病机制与病情相关性.结果 肝源性糖尿病患者、2型糖尿病患者及健康对照者血清25-(OH)D3水平分别是(38.23±12.47),(63.33±13.58),(86.14± 16.25)μmol/L,差异有统计学意义(P＜0.05);肝源性糖尿病患者血清25-(OH)D3水平与肝硬化Child-Pugh积分呈负相关(r=-0.363,P＜0.05).结论 低水平维生素D或是肝源性糖尿病患者发病机制之一.
目的 探討維生素D水平與肝硬化分級相關性.方法 收集肝源性糖尿病患者38例,2型糖尿病患者48例,健康對照者30例,鑑測血清25-(OH) D3水平,併計算Child-Pugh積分,分析肝源性糖尿病髮病機製與病情相關性.結果 肝源性糖尿病患者、2型糖尿病患者及健康對照者血清25-(OH)D3水平分彆是(38.23±12.47),(63.33±13.58),(86.14± 16.25)μmol/L,差異有統計學意義(P＜0.05);肝源性糖尿病患者血清25-(OH)D3水平與肝硬化Child-Pugh積分呈負相關(r=-0.363,P＜0.05).結論 低水平維生素D或是肝源性糖尿病患者髮病機製之一.
목적 탐토유생소D수평여간경화분급상관성.방법 수집간원성당뇨병환자38례,2형당뇨병환자48례,건강대조자30례,감측혈청25-(OH) D3수평,병계산Child-Pugh적분,분석간원성당뇨병발병궤제여병정상관성.결과 간원성당뇨병환자、2형당뇨병환자급건강대조자혈청25-(OH)D3수평분별시(38.23±12.47),(63.33±13.58),(86.14± 16.25)μmol/L,차이유통계학의의(P＜0.05);간원성당뇨병환자혈청25-(OH)D3수평여간경화Child-Pugh적분정부상관(r=-0.363,P＜0.05).결론 저수평유생소D혹시간원성당뇨병환자발병궤제지일.
Objective To observe the correlation between vitamin D and liver cirrhosis classification in hepatic diabetes.Methods Thirty-eight patients with hepatic diabetes,48 patients with type 2 diabetes and 30 cases of healthy controls were collected.The level of serum 25-(OH)D3 was determined,and the Child-Pugh score was calculated.The correlation between pathogenesis and pathogenetic condition of hepatic diabetes was analyzed.Results The levels of serum 25-(OH)D3 in hepatic diabetes patients,type 2 diabetes patients and healthy controls were (38.23 ± 12.47),(63.33 ± 13.58) and (86.14 ± 16.25) μ mol/L,and there was statistical difference (P ＜ 0.05).There was negative correlation in hepatic diabetes between serum 25-(OH)D3 level and liver cirrhosis Child-Pugh score (r =-0.363,P ＜ 0.05).Conclusion Low level of vitamin D may be one of the pathogenesis of hepatic diabetes.
