中华耳鼻咽喉头颈外科杂志
中華耳鼻嚥喉頭頸外科雜誌
중화이비인후두경외과잡지
CHINESE JOURNAL OF OTORHINOLARYNGOLOGY HEAD AND NECK SURGERY
2014年
12期
1013-1016
,共4页
丁秀勇%张汝祥%许长建%樊伟%张道行
丁秀勇%張汝祥%許長建%樊偉%張道行
정수용%장여상%허장건%번위%장도행
耳蜗植入物%诱发电位,听觉,脑干%电刺激%豚鼠
耳蝸植入物%誘髮電位,聽覺,腦榦%電刺激%豚鼠
이와식입물%유발전위,은각,뇌간%전자격%돈서
Cochlear implants%Evoked potentials,auditory,brain stem%Electric stimulation%Guinea pigs
目的 建立REZ-Ⅰ型国产人工耳蜗电诱发听性脑干反应(electrically evoked auditory brainstem response,EABR)模块,并测试其稳定性及可靠性.方法 使用自行设计构建的REZ-Ⅰ型国产人工耳蜗EABR测试模块记录听力正常豚鼠人工耳蜗植入后的EABR,并探索相关技术参数.结果 9只豚鼠(15耳)EABR波形引出率为100％.100μs刺激脉宽的阈值平均(均数±标准差,下同)为(159.00±50.21)电流级(current level,CL),波Ⅲ潜伏期为(2.36 ±0.46) ms;150μs刺激脉宽的阈值为(131.44 ±49.25)CL,波Ⅲ潜伏期为(2.59±0.46)ms;200 μs刺激脉宽的阈值为(119.63 ±52.56)CL,波Ⅲ潜伏期为(2.62±0.44) ms.结论 REZ-Ⅰ型人工耳蜗EABR模块动物实验的引出率达到100％,其稳定性和可靠性能够满足EABR的测试要求.
目的 建立REZ-Ⅰ型國產人工耳蝸電誘髮聽性腦榦反應(electrically evoked auditory brainstem response,EABR)模塊,併測試其穩定性及可靠性.方法 使用自行設計構建的REZ-Ⅰ型國產人工耳蝸EABR測試模塊記錄聽力正常豚鼠人工耳蝸植入後的EABR,併探索相關技術參數.結果 9隻豚鼠(15耳)EABR波形引齣率為100％.100μs刺激脈寬的閾值平均(均數±標準差,下同)為(159.00±50.21)電流級(current level,CL),波Ⅲ潛伏期為(2.36 ±0.46) ms;150μs刺激脈寬的閾值為(131.44 ±49.25)CL,波Ⅲ潛伏期為(2.59±0.46)ms;200 μs刺激脈寬的閾值為(119.63 ±52.56)CL,波Ⅲ潛伏期為(2.62±0.44) ms.結論 REZ-Ⅰ型人工耳蝸EABR模塊動物實驗的引齣率達到100％,其穩定性和可靠性能夠滿足EABR的測試要求.
목적 건립REZ-Ⅰ형국산인공이와전유발은성뇌간반응(electrically evoked auditory brainstem response,EABR)모괴,병측시기은정성급가고성.방법 사용자행설계구건적REZ-Ⅰ형국산인공이와EABR측시모괴기록은력정상돈서인공이와식입후적EABR,병탐색상관기술삼수.결과 9지돈서(15이)EABR파형인출솔위100％.100μs자격맥관적역치평균(균수±표준차,하동)위(159.00±50.21)전류급(current level,CL),파Ⅲ잠복기위(2.36 ±0.46) ms;150μs자격맥관적역치위(131.44 ±49.25)CL,파Ⅲ잠복기위(2.59±0.46)ms;200 μs자격맥관적역치위(119.63 ±52.56)CL,파Ⅲ잠복기위(2.62±0.44) ms.결론 REZ-Ⅰ형인공이와EABR모괴동물실험적인출솔체도100％,기은정성화가고성능구만족EABR적측시요구.
Objective To develop electrically evoked auditory brainstem response(EABR) modules of REZ-Ⅰ domestic cochlear implant device,and testify the reliability and validity of the modules.Methods Postoperative EABR were recorded in guinea pigs by using the self-designed EABR module.Results EABR waves were recorded in all 15 ears of 9 guinea pigs with normal hearing.The threshold was (159.00 ±50.21) current level (CL) and e Ⅲ wave latency was (2.36 ± 0.46)ms of 100 μs pulse width stimulation; for 150 μs pulse width stimulation,the threshold was (131.44 ± 49.25)CL and e Ⅲ wave latency was (2.59 ± 0.46) ms ; for 200 μs pulse width stimulation,the threshold was (119.63 ± 52.56) CL and e Ⅲ wave latency was (2.62 ± 0.44) ms.Conclusion According the preliminary results of the study,the reliability and stability of the EABR modules of domestic cochlear implant device can meet the demands of EABR recording.
