CAJ | 학술논문

目的探讨颈动脉斑块的性质与其社区高危人群常见危险因素之间的关系.方法收集2008年1月至2012年8月经查颈彩超证实有颈动脉斑块形成的广州本地社区高危人群的资料(共235例),以单因素及多因素方法分析颈动脉斑块的性质(扁平斑、硬斑、软斑和溃疡斑)与其常见危险因素的关系.结果单因素分析发现:80岁以上患者溃疡斑明显增多(P=0.042);女性(P=0.000)及高血压(P=0.027)患者软斑的数量明显减少.多因素分析发现:年龄(age)和收缩压(SBP)是影响颈动脉溃疡斑块形成的主要危险因素(ORage=1.043,P=0.030; ORSBP=1.026,P=0.024);女性及SBP是影响软斑形成的主要保护性因素(ORsex=0.321,P=0.000;ORSBP=0.970,P=0.006).结论女性及高血压患者颈动脉软斑生成相对较少,而80岁以上高龄患者溃疡斑相对较多.
목적 탐토경동맥반괴적성질여기사구고위인군상견위험인소지간적관계.방법 수집2008년1월지2012년8월경사경채초증실유경동맥반괴형성적엄주본지사구고위인군적자료(공235례),이단인소급다인소방법분석경동맥반괴적성질(편평반、경반、연반화궤양반)여기상견위험인소적관계.결과 단인소분석발현:80세이상환자궤양반명현증다(P=0.042);녀성(P=0.000)급고혈압(P=0.027)환자연반적수량명현감소.다인소분석발현:년령(age)화수축압(SBP)시영향경동맥궤양반괴형성적주요위험인소(ORage=1.043,P=0.030; ORSBP=1.026,P=0.024);녀성급SBP시영향연반형성적주요보호성인소(ORsex=0.321,P=0.000;ORSBP=0.970,P=0.006).결론 녀성급고혈압환자경동맥연반생성상대교소,이80세이상고령환자궤양반상대교다.
Objective To investigate the relationship between properties of carotid plaques and common risk factors among community high-risk population.Methods From January 2008 to August 2010,the data of 235 subjects from atherosclerotic high-risk population in local communities were collected.The carotid plaques of the subjects were confirmed by color ultrasound.Univariate and multivariate analyses were used to identify the relationship between the properties of carotid plaques (flat,soft,hard and ulcer plaque) and the common risk factors.Results Univariate analyses showed that subjects over 80 years old had much more ulcer plaques than younger ones (P=0.042); females and hypertensive subjects had significantly more soft plaques than males and non-hypertensive ones separately (P=0.000 and P=0.027,respectively).Multivariate analyses discovered that age (older) and systolic blood pressure (SBP) were the key risk factors influencing ulcer plaque formation (ORase=1.043,P=0.030 and ORSBP=1.026,P=0.024,respectively); female and SBP were the protective factors influencing the soft plaque formation (ORsex=0.321,P=0.000 and ORSBP=0.970,P=0.006,respectively).Conclusion Female and hypertensive patients have less soft carotid plaques,and those over 80 years old have more ulcer plaques.