CAJ | 학술논문

微小RNA(miRNA)是一类具有转录后调节功能的非编码单链的小分子RNA,其在肿瘤形成过程中的作用已成为目前研究的热点.大量研究提示多种miRNA的异常表达参与了肝癌的发生发展,并可用于肝癌的诊断、治疗和预后评估.深入探讨miRNA与肝癌的关系及其分子机制将为肝癌的防治提供新的思路和方法.
미소RNA(miRNA)시일류구유전록후조절공능적비편마단련적소분자RNA,기재종류형성과정중적작용이성위목전연구적열점.대량연구제시다충miRNA적이상표체삼여료간암적발생발전,병가용우간암적진단、치료화예후평고.심입탐토miRNA여간암적관계급기분자궤제장위간암적방치제공신적사로화방법.
As a non-coding single-strand small RNA,microRNA (miRNA) plays an important role in post-translational regulation.Its role in tumor formation has become a study hotspot.A large body of studies in dicate that the abnormal expression of miRNA involves in the occurrence and development of liver cancer,which can be used for the diagnosis,therapy and prognosis evaluation of liver cancer.In-depth exploration of the molecular mechanism of miRNA and the relationship between miRNA and liver cancer could provide novel ideas and methods for the therapy and prevention of liver cancer.