中华急诊医学杂志
中華急診醫學雜誌
중화급진의학잡지
CHINESE JOURNAL OF EMERGENCY MEDICINE
2014年
12期
1381-1384
,共4页
汪亨通%项和平%李贺%王天鹏%张长乐
汪亨通%項和平%李賀%王天鵬%張長樂
왕형통%항화평%리하%왕천붕%장장악
血清二胺氧化酶%CT严重度指数评分%胃肠道功能障碍评分%急性生理及慢性健康状况评分Ⅱ%血清降钙素原
血清二胺氧化酶%CT嚴重度指數評分%胃腸道功能障礙評分%急性生理及慢性健康狀況評分Ⅱ%血清降鈣素原
혈청이알양화매%CT엄중도지수평분%위장도공능장애평분%급성생리급만성건강상황평분Ⅱ%혈청강개소원
Serum diamine oxidase%Computed tomography (CT) severity index scores%Gastrointestinal dysfunction score%Acute physiology and chronic health evaluation Ⅱ%Serum calcitonin original
目的 通过研究重症急性胰腺炎(SAP)患者血清二胺氧化酶(DAO)水平变化,探讨DAO在SAP病情严重程度及胃肠道功能障碍程度评估中的作用.方法 选取安徽医科大学第二附属医院急诊科2012年1月至2013年12月收治的56例发病3d内收至入院的SAP患者,入院时抽取血清二胺氧化酶(DAO)标本,同时进行急性生理及慢性健康状况评分Ⅱ(APACHEⅡ)、CT严重度指数(CTSI)及胃肠功能障碍程度评分,并在相应时间点检测患者血清降钙素原(PCT),将血清DAO与这四者进行相关性分析.结果 发现入院时,SAP患者血清DAO水平越高,其相对应的血清PCT浓度(r=0.516,P＜0.01)、APACHEⅡ(r=0.631,P＜0.01)、CTIS(r =0.640,P＜0.01)、胃肠道功能障碍程度(r=0.730,P＜0.01)也越高,血清DAO与其四者均呈正相关.结论 血清DAO在评估SAP患者胃肠功能障碍及疾病严重程度中有一定的预示作用.
目的 通過研究重癥急性胰腺炎(SAP)患者血清二胺氧化酶(DAO)水平變化,探討DAO在SAP病情嚴重程度及胃腸道功能障礙程度評估中的作用.方法 選取安徽醫科大學第二附屬醫院急診科2012年1月至2013年12月收治的56例髮病3d內收至入院的SAP患者,入院時抽取血清二胺氧化酶(DAO)標本,同時進行急性生理及慢性健康狀況評分Ⅱ(APACHEⅡ)、CT嚴重度指數(CTSI)及胃腸功能障礙程度評分,併在相應時間點檢測患者血清降鈣素原(PCT),將血清DAO與這四者進行相關性分析.結果 髮現入院時,SAP患者血清DAO水平越高,其相對應的血清PCT濃度(r=0.516,P＜0.01)、APACHEⅡ(r=0.631,P＜0.01)、CTIS(r =0.640,P＜0.01)、胃腸道功能障礙程度(r=0.730,P＜0.01)也越高,血清DAO與其四者均呈正相關.結論 血清DAO在評估SAP患者胃腸功能障礙及疾病嚴重程度中有一定的預示作用.
목적 통과연구중증급성이선염(SAP)환자혈청이알양화매(DAO)수평변화,탐토DAO재SAP병정엄중정도급위장도공능장애정도평고중적작용.방법 선취안휘의과대학제이부속의원급진과2012년1월지2013년12월수치적56례발병3d내수지입원적SAP환자,입원시추취혈청이알양화매(DAO)표본,동시진행급성생리급만성건강상황평분Ⅱ(APACHEⅡ)、CT엄중도지수(CTSI)급위장공능장애정도평분,병재상응시간점검측환자혈청강개소원(PCT),장혈청DAO여저사자진행상관성분석.결과 발현입원시,SAP환자혈청DAO수평월고,기상대응적혈청PCT농도(r=0.516,P＜0.01)、APACHEⅡ(r=0.631,P＜0.01)、CTIS(r =0.640,P＜0.01)、위장도공능장애정도(r=0.730,P＜0.01)야월고,혈청DAO여기사자균정정상관.결론 혈청DAO재평고SAP환자위장공능장애급질병엄중정도중유일정적예시작용.
Objective To study the change of serum diamine oxidase (DAO) level in patients with severely acute pancreatitis (SAP) in order to explore the role of DAO in assessing the severity of SAP and the magnitude of gastrointestinal dysfunction.Methods From January 2012 through December 2013,56 SAP patients with 33 male and 23 female and average age (45-± 14) years admitted within 3 days after onset were enrolled for this study.At admission,serum diamine oxidase (DAO) was detected,and APACHE Ⅱ score,computed tomography severity index (CTSI) score and Balthazar grading and gastrointestinal dysfunction score were calculated.And at the corresponding time,serum procalcitonin (PCT) was detected.The correlations between serum DAO level and 4 other markers were analyzed.Results The high level of serum DAO was found at admission in SAP patients correlating positively with serum PCT concentrations (r =0.516,P＜ 0.01),APACHE Ⅱ score (r =0.631,P＜ 0.01),CTIS score (r=0.640,P ＜ 0.01),and the degree of gastrointestinal dysfunction (r =0.730,P ＜ 0.01).Conclusions The role of serum DAO in assessing the severity of SAP and magnitude of gastrointestinal dysfunction in SAP patients is really valid.
