中华实验眼科杂志
中華實驗眼科雜誌
중화실험안과잡지
CHINESE JOURNAL OF EXPERIMENTAL OPHTHALMOLOGY
2014年
12期
1097-1101
,共5页
金红颖%姚克%杨亚波%杜新华%邱培瑾
金紅穎%姚剋%楊亞波%杜新華%邱培瑾
금홍영%요극%양아파%두신화%구배근
眼前节光学相干断层扫描%Orbscan角膜地形图%超声角膜测厚仪%中央角膜厚度%前房深度%角膜白到白距离%前房角间距
眼前節光學相榦斷層掃描%Orbscan角膜地形圖%超聲角膜測厚儀%中央角膜厚度%前房深度%角膜白到白距離%前房角間距
안전절광학상간단층소묘%Orbscan각막지형도%초성각막측후의%중앙각막후도%전방심도%각막백도백거리%전방각간거
Anterior segment optical coherence tomography%Orbscan topography%Ultrasonic pachymetry%Central corneal thickness%Anterior chamber depth%White to white corneal distance%Angle to angle distance
背景 近视屈光手术的开展需要我们对患者眼前节的数据进行精确测量和评估.目前临床上有多种仪器和方法可以对患者的眼前节进行生物学测量,但是哪种方法更为精确和方便,仍需进一步探讨.目的 比较眼前节光学相干断层扫描(AS-OCT)、OrbscanⅡ、超声生物测厚仪对近视患者眼前节参数的测量结果.方法 回顾性分析2011年11月至2012年5月于浙江大学医学院附属第二医院眼科中心就诊的拟行角膜屈光手术的近视患者70例140眼,受检者等效球镜度为-0.75 ～-10.25 D.分别用AS-OCT、OrbscanⅡ和超声角膜测厚仪测量角膜中央厚度(CCT),用AS-OCT测量前房深度(ACD)和前房角间距(ATA),用OrbscanⅡ测量ACD和角膜白到白距离(WTW),对3种测量仪器的测量结果进行比较. 结果 AS-OCT、超声角膜测厚仪和OrbscanⅡ测量的平均CCT值分别为(516.57±30.25)、(523.68±31.87)和(514.69±38.40) μm,3种测量仪器间测量结果的总体比较差异无统计学意义(F=2.775,P=0.063).根据超声角膜测厚仪所测的CCT结果将受检者分为＜500μm组、500 ～ 569 μm组和≥570 μm组,＜500 μm组受检者以超声角膜测厚仪测量的CCT值最高,OrbscanⅡ测量值最低,用3种方法测量的CCT值差异有统计学意义(F=22.236,P=0.000);AS-OCT和超声角膜测厚仪的测量值间差异无统计学意义(P＞0.05).500～569 μm组受检者用3种仪器测量的CCT值总体比较差异无统计学意义(F=3.011,P=0.051).≥570 μm组受检者用超声角膜测厚仪测量的CCT最高,AS-OCT测量值最低,3种仪器的测量值总体比较差异有统计学意义(F=4.133,P=0.021),超声角膜测厚仪与Orbscan Ⅱ测量的CCT值差异无统计学意义(P＞0.05).AS-OCT和OrbscanⅡ测量的ACD值分别为(3.83±0.21)mm和(3.75±0.21)mm,二者差异有统计学意义(t=-8.520,P=0.000);AS-OCT测量的ATA为(12.43±0.74) mm,OrbscanⅡ测量的WTW为(11.42±0.33) mm,两种方法间测量的差异有统计学意义(t=-18.088,P=0.000).结论 AS-OCT、超声角膜测厚仪、OrbscanⅡ均可作为角膜屈光手术前测量CCT的方法,3种方法可互为参考.AS-OCT、OrbscanⅡ还可以测量ACD、ATA、WTW,因测量方法及原理不同,结果亦有差异.
揹景 近視屈光手術的開展需要我們對患者眼前節的數據進行精確測量和評估.目前臨床上有多種儀器和方法可以對患者的眼前節進行生物學測量,但是哪種方法更為精確和方便,仍需進一步探討.目的 比較眼前節光學相榦斷層掃描(AS-OCT)、OrbscanⅡ、超聲生物測厚儀對近視患者眼前節參數的測量結果.方法 迴顧性分析2011年11月至2012年5月于浙江大學醫學院附屬第二醫院眼科中心就診的擬行角膜屈光手術的近視患者70例140眼,受檢者等效毬鏡度為-0.75 ～-10.25 D.分彆用AS-OCT、OrbscanⅡ和超聲角膜測厚儀測量角膜中央厚度(CCT),用AS-OCT測量前房深度(ACD)和前房角間距(ATA),用OrbscanⅡ測量ACD和角膜白到白距離(WTW),對3種測量儀器的測量結果進行比較. 結果 AS-OCT、超聲角膜測厚儀和OrbscanⅡ測量的平均CCT值分彆為(516.57±30.25)、(523.68±31.87)和(514.69±38.40) μm,3種測量儀器間測量結果的總體比較差異無統計學意義(F=2.775,P=0.063).根據超聲角膜測厚儀所測的CCT結果將受檢者分為＜500μm組、500 ～ 569 μm組和≥570 μm組,＜500 μm組受檢者以超聲角膜測厚儀測量的CCT值最高,OrbscanⅡ測量值最低,用3種方法測量的CCT值差異有統計學意義(F=22.236,P=0.000);AS-OCT和超聲角膜測厚儀的測量值間差異無統計學意義(P＞0.05).500～569 μm組受檢者用3種儀器測量的CCT值總體比較差異無統計學意義(F=3.011,P=0.051).≥570 μm組受檢者用超聲角膜測厚儀測量的CCT最高,AS-OCT測量值最低,3種儀器的測量值總體比較差異有統計學意義(F=4.133,P=0.021),超聲角膜測厚儀與Orbscan Ⅱ測量的CCT值差異無統計學意義(P＞0.05).AS-OCT和OrbscanⅡ測量的ACD值分彆為(3.83±0.21)mm和(3.75±0.21)mm,二者差異有統計學意義(t=-8.520,P=0.000);AS-OCT測量的ATA為(12.43±0.74) mm,OrbscanⅡ測量的WTW為(11.42±0.33) mm,兩種方法間測量的差異有統計學意義(t=-18.088,P=0.000).結論 AS-OCT、超聲角膜測厚儀、OrbscanⅡ均可作為角膜屈光手術前測量CCT的方法,3種方法可互為參攷.AS-OCT、OrbscanⅡ還可以測量ACD、ATA、WTW,因測量方法及原理不同,結果亦有差異.
배경 근시굴광수술적개전수요아문대환자안전절적수거진행정학측량화평고.목전림상상유다충의기화방법가이대환자적안전절진행생물학측량,단시나충방법경위정학화방편,잉수진일보탐토.목적 비교안전절광학상간단층소묘(AS-OCT)、OrbscanⅡ、초성생물측후의대근시환자안전절삼수적측량결과.방법 회고성분석2011년11월지2012년5월우절강대학의학원부속제이의원안과중심취진적의행각막굴광수술적근시환자70례140안,수검자등효구경도위-0.75 ～-10.25 D.분별용AS-OCT、OrbscanⅡ화초성각막측후의측량각막중앙후도(CCT),용AS-OCT측량전방심도(ACD)화전방각간거(ATA),용OrbscanⅡ측량ACD화각막백도백거리(WTW),대3충측량의기적측량결과진행비교. 결과 AS-OCT、초성각막측후의화OrbscanⅡ측량적평균CCT치분별위(516.57±30.25)、(523.68±31.87)화(514.69±38.40) μm,3충측량의기간측량결과적총체비교차이무통계학의의(F=2.775,P=0.063).근거초성각막측후의소측적CCT결과장수검자분위＜500μm조、500 ～ 569 μm조화≥570 μm조,＜500 μm조수검자이초성각막측후의측량적CCT치최고,OrbscanⅡ측량치최저,용3충방법측량적CCT치차이유통계학의의(F=22.236,P=0.000);AS-OCT화초성각막측후의적측량치간차이무통계학의의(P＞0.05).500～569 μm조수검자용3충의기측량적CCT치총체비교차이무통계학의의(F=3.011,P=0.051).≥570 μm조수검자용초성각막측후의측량적CCT최고,AS-OCT측량치최저,3충의기적측량치총체비교차이유통계학의의(F=4.133,P=0.021),초성각막측후의여Orbscan Ⅱ측량적CCT치차이무통계학의의(P＞0.05).AS-OCT화OrbscanⅡ측량적ACD치분별위(3.83±0.21)mm화(3.75±0.21)mm,이자차이유통계학의의(t=-8.520,P=0.000);AS-OCT측량적ATA위(12.43±0.74) mm,OrbscanⅡ측량적WTW위(11.42±0.33) mm,량충방법간측량적차이유통계학의의(t=-18.088,P=0.000).결론 AS-OCT、초성각막측후의、OrbscanⅡ균가작위각막굴광수술전측량CCT적방법,3충방법가호위삼고.AS-OCT、OrbscanⅡ환가이측량ACD、ATA、WTW,인측량방법급원리불동,결과역유차이.
Background It is essential to measure and assess the parameters of ocular anterior segment for refractive surgery in myopic eyes.Some different imaging devices can be used for biometric measurement of ocular anterior segment,but which is more accurate and convenient is still under investigation.Objective This study was to compare the anterior segment parameters in myopic eyes measured by anterior segment optical coherence tomography (AS-OCT),Orbscan topography and ultrasonic pachymetry (US).Methods One hundred and forty eyes of 70 myopic subjects with the diopter of-0.75 to-10.25 D,who intended to receive corneal refractive surgery in the Second Affiliated Hospital of Zhejiang University School of Medicine from November 2011 to May 2012,were retrospectively analyzed.Central corneal thickness (CCT) was measured using AS-OCT,Orbscan Ⅱ and US,respectively,and anterior chamber depth (ACD) was measured by AS-OCT and Orbscan Ⅱ,and the angle to angle (ATA) distance and corneal white-to-white corneal distance (WTW) were measured by AS-OCT and Orbscan Ⅱ,respectively.The parameters from different apparatuses were statistically compared.Results The mean CCT were (516.57±30.25) μm in AS-OCT,(523.68±31.87) μm in US and (514.69±38.40) μm in Orbscan Ⅱ,without significant difference among them (F =2.775,P =0.063).Then the patients were divided into three groups based on the US measurement of CCT (＜500 μm group,500-569 μm group,and ≥ 570 μm group).In the ＜500 μm group,there was a significant difference in the CCT among the three methods (F =22.236,P =0.000),significant differences were found between AS-OCT and Orbscan Ⅱ,or Orbscan Ⅱ and US(both at P＜0.05).In the 500-569 μm group,there was no significant difference in the CCT among the three methods (F =3.011,P =0.051).In the ≥ 570 μm group,there was a significant difference in the CCT among the three methods (F =4.133,P =0.021),a significant difference was found between AS-OCT and US(P＜0.05),but there was no significant difference between AS-OCT and Orbscan Ⅱ (P＞0.05).The ACD values measured by AS-OCT was (3.83±0.21) mm,which was higher than (3.75 ± 0.21) mm by Orbscan Ⅱ,with a significant difference between them (t =-8.520,P =0.000).In addition,the ATA value by AS-OCT (12.43 mm±0.74 mm) was higher than the WTW value (11.42 mm±0.33 mm) by OrbscanⅡ,with a significant difference between them(t=-18.088,P=0.000).Conclusions AS-OCT,US and Orbscan Ⅱ can offer accurate CCT value,and they can provide references to one another before refractive surgery.However,the ACD,ATA and WTW values by AS-OCT and Orbscan]Ⅱ have large differences.
