中华地方病学杂志
中華地方病學雜誌
중화지방병학잡지
Chinese Journal of Endemiology
2014年
6期
630-632
,共3页
王睿%曾强%侯常春%崔维琪%张磊%冯宝佳%赵亮%崔玉山%刘洪亮
王睿%曾彊%侯常春%崔維琪%張磊%馮寶佳%趙亮%崔玉山%劉洪亮
왕예%증강%후상춘%최유기%장뢰%풍보가%조량%최옥산%류홍량
氟中毒%高碘%氟斑牙%儿童
氟中毒%高碘%氟斑牙%兒童
불중독%고전%불반아%인동
Fluorosis%High iodine%Dental fluorosis%Child
目的 观察高氟高碘饮水对天津市农村学龄儿童氟斑牙患病的影响.方法 依据天津市农村饮用水中氟含量和碘含量的筛查结果,在天津市选择静海县和武清区的3个乡镇分别作为高氟高碘组、高氟适碘组及适氟适碘(对照)组,以8～10岁农村儿童作为调查对象,采集晨尿,氟离子选择电极法(WS/T 89-1996)检测尿氟,砷铈催化分光光度法(WS/T 107-2006)测定尿碘,采用Dean法检查氟斑牙患病情况.应用SPSS 11.5软件对数据进行x2检验、Logistic分析.结果 高氟高碘组、高氟适碘组及对照组儿童尿氟中位数分别为2.48、2.70、1.59 mg/L,尿碘中位数分别为721.7、788.3、293.5 μg/L,组间比较,差异均有统计学意义(x2值分别为35.10、17.01,P均＜0.05).氟斑牙检出率由高至低依次为高氟适碘组(85.3％,29/34)、高氟高碘组(66.7％,14/21)、对照组(48.8％,21/43),组间比较差异有统计学意义(×2=15.39,P＜0.05).Logistic分析表明,高水氟是氟斑牙的患病危险因素[比值比(OR)为7.273,95％可信区间(CI)为1.676 ～ 31.562,x2=7.020,P＜0.05].结论 饮水高氟及高氟高碘慢性暴露对氟斑牙检出率产生一定的影响.
目的 觀察高氟高碘飲水對天津市農村學齡兒童氟斑牙患病的影響.方法 依據天津市農村飲用水中氟含量和碘含量的篩查結果,在天津市選擇靜海縣和武清區的3箇鄉鎮分彆作為高氟高碘組、高氟適碘組及適氟適碘(對照)組,以8～10歲農村兒童作為調查對象,採集晨尿,氟離子選擇電極法(WS/T 89-1996)檢測尿氟,砷鈰催化分光光度法(WS/T 107-2006)測定尿碘,採用Dean法檢查氟斑牙患病情況.應用SPSS 11.5軟件對數據進行x2檢驗、Logistic分析.結果 高氟高碘組、高氟適碘組及對照組兒童尿氟中位數分彆為2.48、2.70、1.59 mg/L,尿碘中位數分彆為721.7、788.3、293.5 μg/L,組間比較,差異均有統計學意義(x2值分彆為35.10、17.01,P均＜0.05).氟斑牙檢齣率由高至低依次為高氟適碘組(85.3％,29/34)、高氟高碘組(66.7％,14/21)、對照組(48.8％,21/43),組間比較差異有統計學意義(×2=15.39,P＜0.05).Logistic分析錶明,高水氟是氟斑牙的患病危險因素[比值比(OR)為7.273,95％可信區間(CI)為1.676 ～ 31.562,x2=7.020,P＜0.05].結論 飲水高氟及高氟高碘慢性暴露對氟斑牙檢齣率產生一定的影響.
목적 관찰고불고전음수대천진시농촌학령인동불반아환병적영향.방법 의거천진시농촌음용수중불함량화전함량적사사결과,재천진시선택정해현화무청구적3개향진분별작위고불고전조、고불괄전조급괄불괄전(대조)조,이8～10세농촌인동작위조사대상,채집신뇨,불리자선택전겁법(WS/T 89-1996)검측뇨불,신시최화분광광도법(WS/T 107-2006)측정뇨전,채용Dean법검사불반아환병정황.응용SPSS 11.5연건대수거진행x2검험、Logistic분석.결과 고불고전조、고불괄전조급대조조인동뇨불중위수분별위2.48、2.70、1.59 mg/L,뇨전중위수분별위721.7、788.3、293.5 μg/L,조간비교,차이균유통계학의의(x2치분별위35.10、17.01,P균＜0.05).불반아검출솔유고지저의차위고불괄전조(85.3％,29/34)、고불고전조(66.7％,14/21)、대조조(48.8％,21/43),조간비교차이유통계학의의(×2=15.39,P＜0.05).Logistic분석표명,고수불시불반아적환병위험인소[비치비(OR)위7.273,95％가신구간(CI)위1.676 ～ 31.562,x2=7.020,P＜0.05].결론 음수고불급고불고전만성폭로대불반아검출솔산생일정적영향.
Objective To investigate the joint effects of excessive fluoride and iodine in drinking water on school-age children's dental fluorosis in the countryside of Tianjin.Methods Based on the screening results of fluorine and iodine contents in drinking water in rural areas of Tianjin,three towns in Jinghai County and Wuqing District of Tianjin were selected as high fluoride and high iodine group,high fluoride and suitable iodine group,suitable fluoride and suitable iodine(control) group.Children aged 8-10 were selected as survey subjects.Morning urine was collected and dental fluorosis was examined.The concentration of urinary iodine was determined using arsenic cerium catalytic spectrophotometry(WS/T 107-2006),and urinary fluoride was detected using fluoride ion selective electrode method (WS/T 89-1996).Dean method was used to check the prevalence of dental fluorosis.Results The urinary iodine median was 721.7,788.3,293.5 μg/L,respectively,and urinary fluorosis median was 2.48,2.70,1.59 mg/L,respectively.Urinary iodine and fluorosis were the highest in high fluoride and high iodine group,followed by high fluoride and suitable iodine group and control group(x2 =35.10,17.01,all P ＜ 0.05).There was a significant difference of prevalence of dental fluorosis among the three groups(x2 =15.39,P＜ 0.05).The prevalence of dental fluorosis was the highest in high fluoride and suitable iodine group(85.3％,29/34),followed by high fluoride and high iodine group(66.7％,14/21) and control group(48.8％,21/43).Multiple Logistic regression analysis showed that the prevalence of dental fluorosis was adversely associated with fluorine concentration in drinking water[OR =7.273,95％ confidence limits(CI):1.676 ～ 31.562,x2 =7.020,P ＜ 0.05].Conclusion Drinking water with high fluoride and exposure of high fluoride combined with high iodine has a definite impact on children's dental fluorosis.
