中华地方病学杂志
中華地方病學雜誌
중화지방병학잡지
Chinese Journal of Endemiology
2014年
6期
667-670
,共4页
阚忠媛%王健辉%王□茜%辛玉梅
闞忠媛%王健輝%王□茜%辛玉梅
감충원%왕건휘%왕□천%신옥매
甲状腺%尿%盐类%碘%监测
甲狀腺%尿%鹽類%碘%鑑測
갑상선%뇨%염류%전%감측
Thyroid%Urine%Salts%Iodine%Monitoring
目的 了解辽宁省碘缺乏病病情现状,掌握食用盐碘浓度调整前人群碘营养水平.方法 采用人口比例概率抽样法,在辽宁省选取30个县(市、区),按地理位置划分为沿海和内陆地区,按人口特征划分为城市和农村地区.每个县(市、区)抽取1个乡(镇、街道办事处),每个乡(镇、街道办事处)抽取1个村(居委会)和1所小学.在每所小学抽取40名8～ 10岁学生,检查甲状腺容积并采集其家中盐样;在抽中的40名学生中,再选取14名学生,采集1份尿样,测定尿碘;每个村(居委会),按东、西、南、北、中5个方位各抽取1份居民饮用水水样,如为集中式供水则采集2份末梢水水样,检测水碘;在每所学校附近选取3个乡(镇、街道办事处),每个乡(镇、街道办事处)抽取孕妇和哺乳期妇女各5人,采集尿样,测定尿碘.儿童甲状腺容积检测采用超声法,盐碘检测采用直接滴定法,尿碘及水碘检测采用砷铈催化分光光度法.结果 共检测8～ 10岁学生1 219名,检出甲状腺肿大29人,甲状腺肿大率为2.4％(国家标准:＜5％).共检测盐样1 219份,盐碘中位数为30.1 mg/kg,碘盐覆盖率为99.3％(1 211/1 219),合格碘盐食用率为97.9％(1 194/1 219).共检测8～ 10岁儿童尿样480份,尿碘中位数为189.0 μg/L(碘适宜:100～ 199 μg/L),尿碘＜20 μg/L的占0.6％ (3/480).共采集居民饮用水水样99份,水碘含量为(5.9±5.7)μg/L.共采集孕妇、哺乳期妇女尿样451、450份,尿碘中位数分别为163.2、151.0μg/L(碘适宜:150 ～ 249 μg/L、＞100μg/L).其中沿海城市孕妇尿碘中位数为135.4 μg/L,沿海农村为138.0 μg/L;内陆城市孕妇尿碘中位数为168.0 μg/L,内陆农村为171.1μg/L;沿海与内陆比较差异有统计学意义(H=14.287 6,P＜ 0.05).结论 辽宁省儿童、孕妇及哺乳期妇女的碘营养状况总体处于适宜水平,但沿海地区孕妇碘营养不足.
目的 瞭解遼寧省碘缺乏病病情現狀,掌握食用鹽碘濃度調整前人群碘營養水平.方法 採用人口比例概率抽樣法,在遼寧省選取30箇縣(市、區),按地理位置劃分為沿海和內陸地區,按人口特徵劃分為城市和農村地區.每箇縣(市、區)抽取1箇鄉(鎮、街道辦事處),每箇鄉(鎮、街道辦事處)抽取1箇村(居委會)和1所小學.在每所小學抽取40名8～ 10歲學生,檢查甲狀腺容積併採集其傢中鹽樣;在抽中的40名學生中,再選取14名學生,採集1份尿樣,測定尿碘;每箇村(居委會),按東、西、南、北、中5箇方位各抽取1份居民飲用水水樣,如為集中式供水則採集2份末梢水水樣,檢測水碘;在每所學校附近選取3箇鄉(鎮、街道辦事處),每箇鄉(鎮、街道辦事處)抽取孕婦和哺乳期婦女各5人,採集尿樣,測定尿碘.兒童甲狀腺容積檢測採用超聲法,鹽碘檢測採用直接滴定法,尿碘及水碘檢測採用砷鈰催化分光光度法.結果 共檢測8～ 10歲學生1 219名,檢齣甲狀腺腫大29人,甲狀腺腫大率為2.4％(國傢標準:＜5％).共檢測鹽樣1 219份,鹽碘中位數為30.1 mg/kg,碘鹽覆蓋率為99.3％(1 211/1 219),閤格碘鹽食用率為97.9％(1 194/1 219).共檢測8～ 10歲兒童尿樣480份,尿碘中位數為189.0 μg/L(碘適宜:100～ 199 μg/L),尿碘＜20 μg/L的佔0.6％ (3/480).共採集居民飲用水水樣99份,水碘含量為(5.9±5.7)μg/L.共採集孕婦、哺乳期婦女尿樣451、450份,尿碘中位數分彆為163.2、151.0μg/L(碘適宜:150 ～ 249 μg/L、＞100μg/L).其中沿海城市孕婦尿碘中位數為135.4 μg/L,沿海農村為138.0 μg/L;內陸城市孕婦尿碘中位數為168.0 μg/L,內陸農村為171.1μg/L;沿海與內陸比較差異有統計學意義(H=14.287 6,P＜ 0.05).結論 遼寧省兒童、孕婦及哺乳期婦女的碘營養狀況總體處于適宜水平,但沿海地區孕婦碘營養不足.
목적 료해요녕성전결핍병병정현상,장악식용염전농도조정전인군전영양수평.방법 채용인구비례개솔추양법,재요녕성선취30개현(시、구),안지리위치화분위연해화내륙지구,안인구특정화분위성시화농촌지구.매개현(시、구)추취1개향(진、가도판사처),매개향(진、가도판사처)추취1개촌(거위회)화1소소학.재매소소학추취40명8～ 10세학생,검사갑상선용적병채집기가중염양;재추중적40명학생중,재선취14명학생,채집1빈뇨양,측정뇨전;매개촌(거위회),안동、서、남、북、중5개방위각추취1빈거민음용수수양,여위집중식공수칙채집2빈말소수수양,검측수전;재매소학교부근선취3개향(진、가도판사처),매개향(진、가도판사처)추취잉부화포유기부녀각5인,채집뇨양,측정뇨전.인동갑상선용적검측채용초성법,염전검측채용직접적정법,뇨전급수전검측채용신시최화분광광도법.결과 공검측8～ 10세학생1 219명,검출갑상선종대29인,갑상선종대솔위2.4％(국가표준:＜5％).공검측염양1 219빈,염전중위수위30.1 mg/kg,전염복개솔위99.3％(1 211/1 219),합격전염식용솔위97.9％(1 194/1 219).공검측8～ 10세인동뇨양480빈,뇨전중위수위189.0 μg/L(전괄의:100～ 199 μg/L),뇨전＜20 μg/L적점0.6％ (3/480).공채집거민음용수수양99빈,수전함량위(5.9±5.7)μg/L.공채집잉부、포유기부녀뇨양451、450빈,뇨전중위수분별위163.2、151.0μg/L(전괄의:150 ～ 249 μg/L、＞100μg/L).기중연해성시잉부뇨전중위수위135.4 μg/L,연해농촌위138.0 μg/L;내륙성시잉부뇨전중위수위168.0 μg/L,내륙농촌위171.1μg/L;연해여내륙비교차이유통계학의의(H=14.287 6,P＜ 0.05).결론 요녕성인동、잉부급포유기부녀적전영양상황총체처우괄의수평,단연해지구잉부전영양불족.
Objective To understand the condition of iodine deficiency disorders,and the iodine nutritional status of population before adjustment of iodine level in edible salt in Liaoning Province.Methods Thirty countries (cites,districts) which were divided into coastal,inland,city,rural areas according to location and population characteristics were sampled by population probability sampling method in the whole province; one township (town,street office) was sampled from each country (city,district); one village (neighborhood) and one school were chosen from each township(town,street office).Forty children aged 8-10 were selected from each school to measure their thyroid volumes and household salt samples were collected to detect their iodine content; fourteen of those 40 children were selected to detect their urinary iodine content.In each village (neighborhood),five drinking water samples were collected in the east,the west,the south,the north and the center positions.Two tap water samples were collected to detect their iodine content if the water supply was centralized.Around each school; three townships were selected,in each township,random urine samples were collected from 5 pregnant women and 5 lactating women to detect their iodine content.Thyroid volume was examined by ultrasound method; the salt iodine was tested by the method of direct titration; iodine content of urine and drinking water was tested by arsenic cerium catalytic spectrophotometry.Results Totally one thousand two hundred and nineteen children aged 8-10 were examined; twenty-nine children were diagnosed goiter,and the goiter rate was 2.4％(national standards:＜ 5％).One thousand two hundred and nineteen edible salt samples were tested,and the median salt iodine level was 30.1 mg/kg.The iodized salt coverage rate was 99.3％(1 211/1 219),and the consumption rate of qualified iodized salt was 97.9％(1 194/1 219).Four hundred and eighty urine samples were tested,and the median urinary iodine level was 189.0 μg/L(suitable content of salt iodine was 100-199 μg/L) ; urinary iodine ＜ 20 μg/L accounted for 0.6％(3/480).Ninety-nine drinking water samples were selected,and the average iodine content of the drinking water was (5.9 ± 5.7)μg/L.Four hundred and fifty-one urine samples of pregnant women and four hundred and fifty urine samples of lactating women were selected,and the median urinary iodine level of pregnant women and lactating women was 163.2,151.0 μg/L(suitable contents of urinary iodine in pregnant women and lactating women were 150-249 μg/L,＞ 100 μg/L).The median urinary iodine of pregnant women was 135.4 μg/L in coastal city,138.0 μg/L in coastal rural,168.0 μg/L in inland city,171.1 μg/L in inland rural.The difference of urinary iodine between coastal region and inland region was significant(H =14.287 6,P ＜ 0.05).Conclusions The iodine nutrition conditions of pregnant women,lactating women and children are adequate in Liaoning Province,but the iodine nutritional status is insufficient in pregnant women from the coastal areas.
