中国实用眼科杂志
中國實用眼科雜誌
중국실용안과잡지
CHINESE JOURNAL OF PRACTICAL OPHTHALMOLOGY
2014年
11期
1333-1337
,共5页
脉络膜厚度%屈光不正%远视%黄斑%光学相干体层摄影术%图像增强技术
脈絡膜厚度%屈光不正%遠視%黃斑%光學相榦體層攝影術%圖像增彊技術
맥락막후도%굴광불정%원시%황반%광학상간체층섭영술%도상증강기술
Choroidal thickness%Refractive errors%Hyperopia%Macular/physiology%Optical coherence tomography%Enhanced depth imaging
目的 观察远视性屈光不正儿童黄斑中心凹下脉络膜厚度.方法 临床病例对照研究.对2013年1～8月在莒县人民医院眼科就诊的92例(184只眼)远视性屈光不正组(远视组)儿童,同龄段48名(96只眼)视力正常(正常组)儿童,将其双眼黄斑中心凹水平和垂直方位进行频域光学相干断层扫描图像增强技术(enhanced depth imaging spectral-domain optical coherence tomography EDI-OCT)检查,测量黄斑中心凹下脉络膜厚度.两组间黄斑中心凹下脉络膜厚度值按眼别、性别、远视程度进行统计学分析,并应用直线相关分析法分析远视组黄斑中心凹下脉络膜厚度值与性别、年龄、logMAR BCVA、等效球镜、平均黄斑中心凹处视网膜厚度值之间的相关性.结果 远视组儿童黄斑中心凹下脉络膜厚度比正常组儿童厚,差异有统计学意义(t =-6.097,P＜0.05).远视组按右左眼别,男女性别统计黄斑中心凹下脉络膜厚度均比正常组厚,差异有统计学意义(t =3.638,5.184,4.647,5.235,P＜0.05).远视组按男女性别的右左眼黄斑中心凹下脉络膜厚度均比正常组厚,差异有统计学意义(t =2.676、4.098,3.601、3.592,P＜0.05).轻、中、重度远视组黄斑中心凹下脉络膜厚度亦均比正常组厚,差异有统计学意义(P＜0.05).轻、中、重三组组间黄斑中心凹下脉络膜厚度值差异无统计学意义(P＞0.05).远视儿童弱视组、非弱视组黄斑中心凹下脉络膜厚度均比正常组厚,差异有统计学意义(P＜0.05),两组之间黄斑中心凹下脉络膜厚度差异无统计学意义(P＞0.05).远视组性别、年龄、logMAR BCVA、等效球镜、黄斑中心凹处视网膜厚度与黄斑中心凹下脉络膜厚度之间差异无统计学意义(r=0.143、-0.044、0.189、0.199、0.018,P＞0.05).结论 EDI-OCT检测到远视性屈光不正儿童的黄斑中心凹下脉络膜厚度比同年龄段正常视力儿童厚,其机制有待进一步探讨.
目的 觀察遠視性屈光不正兒童黃斑中心凹下脈絡膜厚度.方法 臨床病例對照研究.對2013年1～8月在莒縣人民醫院眼科就診的92例(184隻眼)遠視性屈光不正組(遠視組)兒童,同齡段48名(96隻眼)視力正常(正常組)兒童,將其雙眼黃斑中心凹水平和垂直方位進行頻域光學相榦斷層掃描圖像增彊技術(enhanced depth imaging spectral-domain optical coherence tomography EDI-OCT)檢查,測量黃斑中心凹下脈絡膜厚度.兩組間黃斑中心凹下脈絡膜厚度值按眼彆、性彆、遠視程度進行統計學分析,併應用直線相關分析法分析遠視組黃斑中心凹下脈絡膜厚度值與性彆、年齡、logMAR BCVA、等效毬鏡、平均黃斑中心凹處視網膜厚度值之間的相關性.結果 遠視組兒童黃斑中心凹下脈絡膜厚度比正常組兒童厚,差異有統計學意義(t =-6.097,P＜0.05).遠視組按右左眼彆,男女性彆統計黃斑中心凹下脈絡膜厚度均比正常組厚,差異有統計學意義(t =3.638,5.184,4.647,5.235,P＜0.05).遠視組按男女性彆的右左眼黃斑中心凹下脈絡膜厚度均比正常組厚,差異有統計學意義(t =2.676、4.098,3.601、3.592,P＜0.05).輕、中、重度遠視組黃斑中心凹下脈絡膜厚度亦均比正常組厚,差異有統計學意義(P＜0.05).輕、中、重三組組間黃斑中心凹下脈絡膜厚度值差異無統計學意義(P＞0.05).遠視兒童弱視組、非弱視組黃斑中心凹下脈絡膜厚度均比正常組厚,差異有統計學意義(P＜0.05),兩組之間黃斑中心凹下脈絡膜厚度差異無統計學意義(P＞0.05).遠視組性彆、年齡、logMAR BCVA、等效毬鏡、黃斑中心凹處視網膜厚度與黃斑中心凹下脈絡膜厚度之間差異無統計學意義(r=0.143、-0.044、0.189、0.199、0.018,P＞0.05).結論 EDI-OCT檢測到遠視性屈光不正兒童的黃斑中心凹下脈絡膜厚度比同年齡段正常視力兒童厚,其機製有待進一步探討.
목적 관찰원시성굴광불정인동황반중심요하맥락막후도.방법 림상병례대조연구.대2013년1～8월재거현인민의원안과취진적92례(184지안)원시성굴광불정조(원시조)인동,동령단48명(96지안)시력정상(정상조)인동,장기쌍안황반중심요수평화수직방위진행빈역광학상간단층소묘도상증강기술(enhanced depth imaging spectral-domain optical coherence tomography EDI-OCT)검사,측량황반중심요하맥락막후도.량조간황반중심요하맥락막후도치안안별、성별、원시정도진행통계학분석,병응용직선상관분석법분석원시조황반중심요하맥락막후도치여성별、년령、logMAR BCVA、등효구경、평균황반중심요처시망막후도치지간적상관성.결과 원시조인동황반중심요하맥락막후도비정상조인동후,차이유통계학의의(t =-6.097,P＜0.05).원시조안우좌안별,남녀성별통계황반중심요하맥락막후도균비정상조후,차이유통계학의의(t =3.638,5.184,4.647,5.235,P＜0.05).원시조안남녀성별적우좌안황반중심요하맥락막후도균비정상조후,차이유통계학의의(t =2.676、4.098,3.601、3.592,P＜0.05).경、중、중도원시조황반중심요하맥락막후도역균비정상조후,차이유통계학의의(P＜0.05).경、중、중삼조조간황반중심요하맥락막후도치차이무통계학의의(P＞0.05).원시인동약시조、비약시조황반중심요하맥락막후도균비정상조후,차이유통계학의의(P＜0.05),량조지간황반중심요하맥락막후도차이무통계학의의(P＞0.05).원시조성별、년령、logMAR BCVA、등효구경、황반중심요처시망막후도여황반중심요하맥락막후도지간차이무통계학의의(r=0.143、-0.044、0.189、0.199、0.018,P＞0.05).결론 EDI-OCT검측도원시성굴광불정인동적황반중심요하맥락막후도비동년령단정상시력인동후,기궤제유대진일보탐토.
Objective To observe the subfoveal choroidal thickness of the children with hyperopic refractive errors.Methods A total of 92 cases (184 eyes) of the hyperopia group and 48 cases (96 eyes) of the normal group in the same age segment were scanned horizontally and vertically on the fovea by enhanced depth imaging spectral-domain optical coherence tomography (EDI-OCT),the value of subfoveal choroidal thickness were measured.Between hyperopia and normal group,the difference of the subfoveal choroidal thickness values was compared using t test of two independent samples.The average thickness of the eyes between the different types was compared using the paired-t-test.The average values of difference diopter group; amblyopia group and non-amblyopia group between the thickness of macular subfoveal choroidal and macular retina was compared using Univariat Analysis Of Variance (ANOVA).Changes in each group were assessed using LSD-t test.The relationship between subfoveal choroidal thickness and gender,age,logMAR BCVA,spherical equivalent,macular retinal thickness in the hyperopia group was compared using linear correlation analysis.P ＜0.05 was considered statistically significant.Results The average thickness of subfoveal choroidal of the hyperopia group was thicker than the normal group.The difference was statistically significant (t =-6.097,P ＜0.05).The average thickness of subfoveal choroidal of the right eyes,the left eyes,the man,the woman in the hyperopia group were all thicker than that in the normal group.The difference was statistically significant (t =3.638,5.184,4.647,5.235,P ＜0.05).The average subfoveal choroidal thickness of the hyperopia group was thicker than that in the normal group,whatever the right eyes or left eyes,between the male and the female.The difference was statistically significant (t =2.676,4.098,3.601,3.592,P ＜0.05).In the mild,moderate,severe hyperopia group,the subfoveal choroidal thickness was all thicker than the normal group,the difference was statistically significant (P ＜0.05).But it had no difference among the three groups (P ＞0.05).In the amblyopia group and non-amblyopia group the subfoveal choroidal thickness was all thicker than the normal group,the difference was statistically significant (P ＜0.05).But it had no difference among the three groups (P ＞0.05).In the hyperopia group,the sex,age,logMAR BCVA,equivalent spherical and the average macular retinal thickness had no significant correlation with the subfoveal choroidal thickness (r =0.143,-0.044,0.189,0.199,0.018,P ＞0.05).Conclusions EDI-OCT detect that the subfoveal choroidal thickness of the children with hyperopic refractive errors is thicker than the normal children with the same age.The mechanism of it needs to be explored further.
