中华放射医学与防护杂志
中華放射醫學與防護雜誌
중화방사의학여방호잡지
Chinese Journal of Radiological Medicine and Protection
2014年
12期
916-918
,共3页
侯栋梁%房彤%刘博%宋丽楠%孙保锦%陈力
侯棟樑%房彤%劉博%宋麗楠%孫保錦%陳力
후동량%방동%류박%송려남%손보금%진력
靶区勾画%食管肿瘤%磁共振扩散加权成像%图像融合
靶區勾畫%食管腫瘤%磁共振擴散加權成像%圖像融閤
파구구화%식관종류%자공진확산가권성상%도상융합
Target delineation%Esophageal neoplasm%Diffusion-weighted magnetic resonance imaging%Image fusion
目的 比较定位CT图像和CT与磁共振扩散加权成像(MR DWI)融合图像(CT/MRDWI)对食管癌放疗GTV勾画的差异.方法 收集经细胞学或组织病理学证实的20例行根治性放疗的食管鳞癌患者,由6名放疗科医师分别在Pinnacle工作站的定位CT图像上和CT/MR DWI融合图像上勾画食管癌原发灶GTV,不包括转移淋巴结.计算GTV体积的均数、标准差、变异系数(CV=标准差/均数),最大值与最小值的比(Ratio=最大值/最小值).比较两组间GTV体积的变异系数CV和最大值与最小值的比值(Ratio)的差异.结果 CT图像上勾画的GTV体积最大差值为55.71 cm3,CT/MR DWI融合图像上勾画的GTV体积最大差值为13.89 cm3(F=12.80,P＜0.05),两组GTV体积的变异系数分别为0.30±0.08和0.11±0.04,两组GTV体积最大值与最小值的比值分别为2.38±0.62和1.34±0.13,差异有统计学意义(Z=-3.92、-3.92,P＜0.05).结论 和定位CT图像相比,CT/MR DWI图像融合显示食管癌GTV较为直观,能够在一定程度上提高判断病变范围的一致性,从而减少不同医师间勾画靶区差异性.
目的 比較定位CT圖像和CT與磁共振擴散加權成像(MR DWI)融閤圖像(CT/MRDWI)對食管癌放療GTV勾畫的差異.方法 收集經細胞學或組織病理學證實的20例行根治性放療的食管鱗癌患者,由6名放療科醫師分彆在Pinnacle工作站的定位CT圖像上和CT/MR DWI融閤圖像上勾畫食管癌原髮竈GTV,不包括轉移淋巴結.計算GTV體積的均數、標準差、變異繫數(CV=標準差/均數),最大值與最小值的比(Ratio=最大值/最小值).比較兩組間GTV體積的變異繫數CV和最大值與最小值的比值(Ratio)的差異.結果 CT圖像上勾畫的GTV體積最大差值為55.71 cm3,CT/MR DWI融閤圖像上勾畫的GTV體積最大差值為13.89 cm3(F=12.80,P＜0.05),兩組GTV體積的變異繫數分彆為0.30±0.08和0.11±0.04,兩組GTV體積最大值與最小值的比值分彆為2.38±0.62和1.34±0.13,差異有統計學意義(Z=-3.92、-3.92,P＜0.05).結論 和定位CT圖像相比,CT/MR DWI圖像融閤顯示食管癌GTV較為直觀,能夠在一定程度上提高判斷病變範圍的一緻性,從而減少不同醫師間勾畫靶區差異性.
목적 비교정위CT도상화CT여자공진확산가권성상(MR DWI)융합도상(CT/MRDWI)대식관암방료GTV구화적차이.방법 수집경세포학혹조직병이학증실적20례행근치성방료적식관린암환자,유6명방료과의사분별재Pinnacle공작참적정위CT도상상화CT/MR DWI융합도상상구화식관암원발조GTV,불포괄전이림파결.계산GTV체적적균수、표준차、변이계수(CV=표준차/균수),최대치여최소치적비(Ratio=최대치/최소치).비교량조간GTV체적적변이계수CV화최대치여최소치적비치(Ratio)적차이.결과 CT도상상구화적GTV체적최대차치위55.71 cm3,CT/MR DWI융합도상상구화적GTV체적최대차치위13.89 cm3(F=12.80,P＜0.05),량조GTV체적적변이계수분별위0.30±0.08화0.11±0.04,량조GTV체적최대치여최소치적비치분별위2.38±0.62화1.34±0.13,차이유통계학의의(Z=-3.92、-3.92,P＜0.05).결론 화정위CT도상상비,CT/MR DWI도상융합현시식관암GTV교위직관,능구재일정정도상제고판단병변범위적일치성,종이감소불동의사간구화파구차이성.
Objective To evaluate the difference between CT and CT/MR DWI images for gross tumor volume (GTV) delineation in precision radiotherapy for esophageal squamous cell carcinoma.Methods 20 patients with pathologically confirmed as esophageal squamous cell carcinoma were selected for target delineation.The GTV based on CT and CT/MR DWI images of the patients were delineated by six radiation oncologists.The mean,standard deviation,coefficient of variation (CV =standard deviation/mean) of GTV volume,the ratio of minimum value and maximum value (ratio =maximum value/minimum value) of the GTV volume were calculated.And the CV and ratio of the GTV by the two methods were compared.Results The biggest difference of GTV volume on CT and on CT/MR DWI images was 55.71 and 13.89 cm3 (F =12.80,P ＜ 0.05).The CV on CT and CT/MR DWI images were 0.30 ± 0.08,0.11-±0.04 (Z =-3.92,P ＜ 0.05),and the ratio of GTV volume were 2.38 ± 0.62,1.34 ± 0.13,respectively (Z =-3.92,P ＜ 0.05).Conclusions CT/MR DWI images could display GTV more directly,which may help to increase consistency of GTV for esophageal squamous cell carcinoma delineation among different radiation oncologists.
