CAJ | 학술논문

目的了解湖州地区无偿献血人群丙肝患病率和流行特征.方法对无偿献血中ELISA检测抗-HCV阳性标本再进行RIBA和PCR确认以及基因分型检测,收集确认阳性献血者人口特征资料进行统计分析.结果湖州地区无偿献血人群HCV患病率为0.84±0.04‰,流行的亚型主要为1b型,患病率和亚型的分布与献血者年龄、性别、学历以及献血次数密切相关(P＜001).结论湖州地区无偿献血人群HCV感染率较低,在不同献血人群中感染率和亚型分布差异明显.
목적 료해호주지구무상헌혈인군병간환병솔화류행특정.방법 대무상헌혈중ELISA검측항-HCV양성표본재진행RIBA화PCR학인이급기인분형검측,수집학인양성헌혈자인구특정자료진행통계분석.결과 호주지구무상헌혈인군HCV환병솔위0.84±0.04‰,류행적아형주요위1b형,환병솔화아형적분포여헌혈자년령、성별、학력이급헌혈차수밀절상관(P＜001).결론 호주지구무상헌혈인군HCV감염솔교저,재불동헌혈인군중감염솔화아형분포차이명현.
Objective To estimate the prevalence of anti-hepatitis C virus (HCV) positivity among blood donors from Huzhou,and to determine risk factors associated with infection.Methods Data were collected from volunteer blood donors between 2009 and 2013.Anti-HCV test and the confirmation test with RIBA and RT-PCR were performed.Information about voluntary blood donors was colleted,then donors who were confirmed HCV seropositive were retrospectively analyzed by statistical comparison.Result The prevalence of anti-HCV positivity was (0.84 ± 0.04) ‰.The predominant genotype currently circulating in Huzhou area was 1 b.There were obvious difference in the incidence among different volunteer blood donors (P ＜ 0 01).Conclusion The rate of HCV infection was much lower in Huzhou area,and there were obvious difference in the incidence and genotype among different volunteer blood donors.