中华实验外科杂志
中華實驗外科雜誌
중화실험외과잡지
CHINESE JOURNAL OF EXPERIMENTAL SURGERY
2014年
12期
2903-2904
,共2页
徐卫波%侯俊清%刘广超%杜信毅%李铁强%朱朝阳
徐衛波%侯俊清%劉廣超%杜信毅%李鐵彊%硃朝暘
서위파%후준청%류엄초%두신의%리철강%주조양
肾细胞癌%细胞核增殖抗原%生物学行为
腎細胞癌%細胞覈增殖抗原%生物學行為
신세포암%세포핵증식항원%생물학행위
Renal cell carcinoma%Proliferation cell nuclear antigen%Biological behavior
目的 探讨细胞核增殖抗原(Ki-67)在肾细胞癌组织中表达的临床意义.方法 应用免疫组织化学方法检测Ki-67在70例肾细胞癌组织及30例正常肾脏组织中的表达.结果 肾细胞癌组织中Ki-67表达阳性率为64.29％-Ki-67表达与肾细胞癌分级、分期明显相关(P＜0.05),与肾癌的病理类型无明显相关(P＞0.05).结论 检测Ki-67有助于反映肾细胞癌生物学行为.
目的 探討細胞覈增殖抗原(Ki-67)在腎細胞癌組織中錶達的臨床意義.方法 應用免疫組織化學方法檢測Ki-67在70例腎細胞癌組織及30例正常腎髒組織中的錶達.結果 腎細胞癌組織中Ki-67錶達暘性率為64.29％-Ki-67錶達與腎細胞癌分級、分期明顯相關(P＜0.05),與腎癌的病理類型無明顯相關(P＞0.05).結論 檢測Ki-67有助于反映腎細胞癌生物學行為.
목적 탐토세포핵증식항원(Ki-67)재신세포암조직중표체적림상의의.방법 응용면역조직화학방법검측Ki-67재70례신세포암조직급30례정상신장조직중적표체.결과 신세포암조직중Ki-67표체양성솔위64.29％-Ki-67표체여신세포암분급、분기명현상관(P＜0.05),여신암적병리류형무명현상관(P＞0.05).결론 검측Ki-67유조우반영신세포암생물학행위.
Objective To explore the clinical significance of proliferation cell nuclear antigen (Ki-67) expression in renal cell carcinoma (RCC).Methods The immunohistochemistry staining method was used to evaluate the expression of Ki-67 in 70 cases of RCC and 30 cases of normal renal tissue as controls.Results The positive expression rate of Ki-67 was 64.29％ in RCC.The positive expression rate of Ki-67 in RCC was significantly related to the clinical stage or clinical grade (P ＜ 0.05),but not to the types of RCC (P ＞0.05).Conclusion Ki-67 is an objective marker to estimate the behaviors of RCC.
