CAJ | 학술논문

目的观察低能量氦氖激光照射头部运动功能区对急性脑梗死患者预后相关因素的影响.方法选取急性脑梗死住院患者358例,随机分常规组(120例)、照射组(118例)、对照组(120例).常规组患者采用神经内科常规治疗方法,照射组和对照组在常规组治疗方案的基础上于发病后72 h开始进行氦氖激光和红光头部运动功能区照射.于治疗前、治疗后1个月和治疗后3个月分别检测3组患者的血液流变、血脂、同型半胱氨酸水平,并于治疗3个月后采用Baahel指数(BI)评定3组患者的日常生活活动能力.结果治疗1个月和3个月后,照射组高切全血黏度、血浆黏度和纤维蛋白原均显著低于对照组和常规组的同时间点,差异均有统计学意义(P＜0.05).治疗1个月后,照射组低切全血黏度为(6.41 ±0.58)mpa·s,显著低于对照组和常规组的同时间点,差异有统计学意义(P＜0.05).治疗1个月和3个月后,照射组的TG、LDL-C和Hcy含量均显著低于常规组和对照组同时间点,差异有统计学意义(P＜0.05);治疗3个月后,照射组TC含量为(4.20 ±0.18)mmol/L,显著低于常规组和对照组同时间点,差异有统计学意义(P＜0.05).治疗后3个月,照射组BI指数显示,生活独立和轻度依赖分别为27例和48例,显著优于常规组的18例和35例,以及对照组的20例和32例.结论低能量氦氖激光头部功能区照射可促进急性脑梗死患者的神经功能恢复,具有临床辅助治疗作用.
목적 관찰저능량양내격광조사두부운동공능구대급성뇌경사환자예후상관인소적영향.방법 선취급성뇌경사주원환자358례,수궤분상규조(120례)、조사조(118례)、대조조(120례).상규조환자채용신경내과상규치료방법,조사조화대조조재상규조치료방안적기출상우발병후72 h개시진행양내격광화홍광두부운동공능구조사.우치료전、치료후1개월화치료후3개월분별검측3조환자적혈액류변、혈지、동형반광안산수평,병우치료3개월후채용Baahel지수(BI)평정3조환자적일상생활활동능력.결과 치료1개월화3개월후,조사조고절전혈점도、혈장점도화섬유단백원균현저저우대조조화상규조적동시간점,차이균유통계학의의(P＜0.05).치료1개월후,조사조저절전혈점도위(6.41 ±0.58)mpa·s,현저저우대조조화상규조적동시간점,차이유통계학의의(P＜0.05).치료1개월화3개월후,조사조적TG、LDL-C화Hcy함량균현저저우상규조화대조조동시간점,차이유통계학의의(P＜0.05);치료3개월후,조사조TC함량위(4.20 ±0.18)mmol/L,현저저우상규조화대조조동시간점,차이유통계학의의(P＜0.05).치료후3개월,조사조BI지수현시,생활독립화경도의뢰분별위27례화48례,현저우우상규조적18례화35례,이급대조조적20례화32례.결론 저능량양내격광두부공능구조사가촉진급성뇌경사환자적신경공능회복,구유림상보조치료작용.
Objective To observe the effect on prognostic factors of low-energy helium-neon laser irradiation of functional areas of the head in patients with acute cerebral infarction.Methods Three-hundred fifty-eight acute cerebral infarction patients were randomly divided into a regular group (120 cases),a treatment group (118 cases) and a control group (120 cases).The patients in the regular group were given the conventional neurological treatment,while those in the treatment group and control group were treated using helium-neon laser and normal red light.The functional areas of the head were irradiated at 72 h after the incidence of disease on the basis of the conventional regimen.The hemorheology,blood lipid and homocysteine (HCY) levels of patients in all 3 groups were measured before treatment,1 month afterward(M1) and 3 months afterward (M3).Their ability in activities of daily living (ADL) was also evaluated using Barthel Index (BI) at 3 months after the treatment.Results At M1 and M3 the average whole blood viscosity at high shear rate,plasma viscosity,fibrinogen triglyceride (TG),high-density lipoprotein cholesterol (HDL-C) and HCY in the treatment group were significantly lower than in the regular and control group (P ＜ 0.05).At M1,the average whole blood viscosity at low shear rate (6.41 ± 0.58 mpa * s) in the treatment group was also significantly lower than that in the other 2 groups (P ＜ 0.05).At M3,the average total cholesterol (TC) in the treatment group (4.20 ± 0.18 mmol/L) was significantly lower compared with that in the regular and control group (P ＜ 0.05).According to the average BI scores,ADL in the treatment group (27 cases of independence/48 cases of mild dependence) were significantly better than that in the regular group (18/35 cases) and the control group (20/32 cases).Conclusions Low-energy helium-neon laser irradiation of the head's functional regions may promote the recovery of neurological function for cerebral infarction patients,and can be an adjuvant therapy in clinical practice.