中华心血管病杂志
中華心血管病雜誌
중화심혈관병잡지
Chinese Journal of Cardiology
2014年
12期
1006-1009
,共4页
高血压,肺性%发病率%超声心动描记术%心脏导管插入术%药物疗法
高血壓,肺性%髮病率%超聲心動描記術%心髒導管插入術%藥物療法
고혈압,폐성%발병솔%초성심동묘기술%심장도관삽입술%약물요법
Hypertension,pulmonary%Incidence%Echocardiography%Heart catheterization%Drug therapy
目的 分析湘雅医院收治的肺高血压患者的分类及其诊治情况.方法 本研究为回顾性研究.收集中南大学湘雅医院2009年1月至2013年11月诊断为肺高血压的住院患者1003例的临床资料,分析其肺高血压分类的构成比、临床特征及诊断和治疗情况.结果 1003例肺高血压患者占同期住院总人数的2.30％.肺高血压构成以先天性心脏病相关肺动脉高压(CHD-PAH)为主(682例,68.00％),其次为结缔组织病相关肺动脉高压(CTD-PAH,117例,11.67％),再次为左心瓣膜性心脏病相关肺高血压(VHD-PH,113例,11.26％),然后为特发性肺动脉高压(IPAH,50例,4.99％)和低氧血症相关肺高血压(20例,2.00％),5年来CHD-PAH构成比呈减少趋势,VHD-PH呈增加趋势.行右心导管检查的患者253例,超声心动图与右心导管诊断符合率为74.00％(187/253).肺高血压住院患者行右心导管检查的比率为18.64％(187/1 003),排除CHD-PAH和VHD-PH两类患者后为40.38％(84/208).予以靶向药物治疗的PH患者186例,排除CHD-PAH和VHD-PH两类患者后为76.44％ (159/208),以单药治疗为主[84.90％(135/159)].结论 中南大学湘雅医院肺高血压分类构成比稳定,以CHD-PAH和CTD-PAH为主,右心导管检查比率较低,靶向药物治疗比率较高,以单药治疗为主.
目的 分析湘雅醫院收治的肺高血壓患者的分類及其診治情況.方法 本研究為迴顧性研究.收集中南大學湘雅醫院2009年1月至2013年11月診斷為肺高血壓的住院患者1003例的臨床資料,分析其肺高血壓分類的構成比、臨床特徵及診斷和治療情況.結果 1003例肺高血壓患者佔同期住院總人數的2.30％.肺高血壓構成以先天性心髒病相關肺動脈高壓(CHD-PAH)為主(682例,68.00％),其次為結締組織病相關肺動脈高壓(CTD-PAH,117例,11.67％),再次為左心瓣膜性心髒病相關肺高血壓(VHD-PH,113例,11.26％),然後為特髮性肺動脈高壓(IPAH,50例,4.99％)和低氧血癥相關肺高血壓(20例,2.00％),5年來CHD-PAH構成比呈減少趨勢,VHD-PH呈增加趨勢.行右心導管檢查的患者253例,超聲心動圖與右心導管診斷符閤率為74.00％(187/253).肺高血壓住院患者行右心導管檢查的比率為18.64％(187/1 003),排除CHD-PAH和VHD-PH兩類患者後為40.38％(84/208).予以靶嚮藥物治療的PH患者186例,排除CHD-PAH和VHD-PH兩類患者後為76.44％ (159/208),以單藥治療為主[84.90％(135/159)].結論 中南大學湘雅醫院肺高血壓分類構成比穩定,以CHD-PAH和CTD-PAH為主,右心導管檢查比率較低,靶嚮藥物治療比率較高,以單藥治療為主.
목적 분석상아의원수치적폐고혈압환자적분류급기진치정황.방법 본연구위회고성연구.수집중남대학상아의원2009년1월지2013년11월진단위폐고혈압적주원환자1003례적림상자료,분석기폐고혈압분류적구성비、림상특정급진단화치료정황.결과 1003례폐고혈압환자점동기주원총인수적2.30％.폐고혈압구성이선천성심장병상관폐동맥고압(CHD-PAH)위주(682례,68.00％),기차위결체조직병상관폐동맥고압(CTD-PAH,117례,11.67％),재차위좌심판막성심장병상관폐고혈압(VHD-PH,113례,11.26％),연후위특발성폐동맥고압(IPAH,50례,4.99％)화저양혈증상관폐고혈압(20례,2.00％),5년래CHD-PAH구성비정감소추세,VHD-PH정증가추세.행우심도관검사적환자253례,초성심동도여우심도관진단부합솔위74.00％(187/253).폐고혈압주원환자행우심도관검사적비솔위18.64％(187/1 003),배제CHD-PAH화VHD-PH량류환자후위40.38％(84/208).여이파향약물치료적PH환자186례,배제CHD-PAH화VHD-PH량류환자후위76.44％ (159/208),이단약치료위주[84.90％(135/159)].결론 중남대학상아의원폐고혈압분류구성비은정,이CHD-PAH화CTD-PAH위주,우심도관검사비솔교저,파향약물치료비솔교고,이단약치료위주.
Objective To analyze the classification and composition change of hospitalized patients with pulmonary hypertension (PH) in our hospital during recent 5 years.Methods This retrospective analysis was performed for hospitalized patients with PH between January 2009 and November 2013.Results A total of 1 003 patients diagnosed with PH were included,the PH-to-total discharged patients ratio was 2.30％.Majority PH (682,68.00％) was originated from congenital heart diseases (CHD-PH),11.67％ (117) from connective tissue diseases,11.26％ (113) from valvular heart diseases,4.99％ (50) from idiopathic,2.00％ (20) from respiratory diseases.The CHD-PH decreased gradually (P =0.041) while the VHD-PH increased gradually (P =0.017),especially in 2013.The percentage of right cardiac catheterization examination in this PH cohort was 18.64％ (187/1 003).Excluding CHD-PAH and VHD-PH,the ratio of right cardiac catheterization examination in PH patients was 40.38％ (84/208).Correct PH diagnosis by echocardiography was 74.00％ (187/253) according to right cardiac catheterization examination.A total of 186 PH patients received pulmonary vascular-targeted medication,84.90％ patients were treated with mono-therapy.Conclusion The clinical data from Xiangya hospital in 2009-2013 shows a stable composition of hospitalized patients with PH,the rate of right cardiac catheterization in these patients is low and the rate of specific target treatment of PH is high (mostly mono-therapy) excluding CHD-PAH and VHD-PH patients.
