累及黄斑的孔源性视网膜脱离患眼手术前后黄斑区多焦视网膜电图及中心视野比较
루급황반적공원성시망막탈리환안수술전후황반구다초시망막전도급중심시야비교
Comparisons of multifocal electroretinogram and central visual field before and after surgery in patients with rhegmatogenous retinal detachment involving the macular area
  • 万方数据
    中华眼底病杂志 중화안저병잡지
    CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
    2014年 6期 566-570 ,共5页

    刘刚%贾万程%王静%张春娣

    류강%가만정%왕정%장춘제

    视网膜脱离/外科学%视觉障碍/病理生理学%黄斑%视网膜电描记术%视野 視網膜脫離/外科學%視覺障礙/病理生理學%黃斑%視網膜電描記術%視野
    시망막탈리/외과학%시각장애/병리생이학%황반%시망막전묘기술%시야
    Retinal detachment/surgery%Vision disorders/physiopathology%Macula lutea%Electroretinography%Visual fields
    目的 观察累及黄斑的孔源性视网膜脱离(RRD)患眼手术前后黄斑区多焦视网膜电图(mfERG)及中心视野变化.方法 回顾性研究.累及黄斑的RRD患者16例16只眼(RRD组)及年龄与之匹配的正常者20名20只眼(正常对照组)纳入研究.RRD组患眼均行巩膜扣带手术治疗.手术前及手术后1、3、6个月,行mfERG及中心视野检查,观察RRD组及正常对照组受检眼的黄斑区反应波振幅密度和潜伏期,以及4°视野平均敏感度(MS).分析RRD组患眼黄斑区反应波振幅密度、潜伏期与MS的相关性以及正常对照组、RRD组mfERG与视野检查的一致性.结果 与正常对照组比较,手术前RRD组患眼黄斑区反应波N1、P1波振幅密度降低、潜伏期延长,差异均有统计学意义(P＜0.05).手术后1、3、6个月RRD组患眼与手术前比较,患眼黄斑区反应波N1、P1波振幅密度明显提高、潜伏期缩短,差异均有统计学意义(P＜0.05).与正常对照组比较,RRD组患眼手术后1、3、6个月黄斑区反应波N1、P1波振幅密度降低、潜伏期延长,差异均有统计学意义(P＜0.05).手术前RRD组患眼4°视野MS值较正常对照组明显降低,差异有统计学意义(t=49.752,P＜0.05).RRD组患眼手术后1、3、6个月4°视野MS值较手术前提高,差异均有统计学意义(t=-9.580、-16.533、-19.580,P＜0.05);但均低于正常对照组,差异也有统计学意义(t=-6.286、-7.493、-6.366,P＜0.05).相关性分析结果显示,手术后1、3、6个月,RRD组患眼黄斑区反应波振幅密度与MS呈正相关(P＜0.05),潜伏期与MS无相关性(P＜0.05).正常对照组、RRD组mfERG与视野检查一致性较好(K=0.886,P＜0.05).结论 累及黄斑的RRD患眼与正常对照眼mfERG、中心视野比较,手术前后黄斑区反应波N1、P1波振幅密度降低、潜伏期延长,MS值降低;与手术前mfERG、中心视野比较,手术后黄斑区反应波N1、P1波振幅密度明显提高、潜伏期缩短,MS值提高.
    목적 관찰루급황반적공원성시망막탈리(RRD)환안수술전후황반구다초시망막전도(mfERG)급중심시야변화.방법 회고성연구.루급황반적RRD환자16례16지안(RRD조)급년령여지필배적정상자20명20지안(정상대조조)납입연구.RRD조환안균행공막구대수술치료.수술전급수술후1、3、6개월,행mfERG급중심시야검사,관찰RRD조급정상대조조수검안적황반구반응파진폭밀도화잠복기,이급4°시야평균민감도(MS).분석RRD조환안황반구반응파진폭밀도、잠복기여MS적상관성이급정상대조조、RRD조mfERG여시야검사적일치성.결과 여정상대조조비교,수술전RRD조환안황반구반응파N1、P1파진폭밀도강저、잠복기연장,차이균유통계학의의(P＜0.05).수술후1、3、6개월RRD조환안여수술전비교,환안황반구반응파N1、P1파진폭밀도명현제고、잠복기축단,차이균유통계학의의(P＜0.05).여정상대조조비교,RRD조환안수술후1、3、6개월황반구반응파N1、P1파진폭밀도강저、잠복기연장,차이균유통계학의의(P＜0.05).수술전RRD조환안4°시야MS치교정상대조조명현강저,차이유통계학의의(t=49.752,P＜0.05).RRD조환안수술후1、3、6개월4°시야MS치교수술전제고,차이균유통계학의의(t=-9.580、-16.533、-19.580,P＜0.05);단균저우정상대조조,차이야유통계학의의(t=-6.286、-7.493、-6.366,P＜0.05).상관성분석결과현시,수술후1、3、6개월,RRD조환안황반구반응파진폭밀도여MS정정상관(P＜0.05),잠복기여MS무상관성(P＜0.05).정상대조조、RRD조mfERG여시야검사일치성교호(K=0.886,P＜0.05).결론 루급황반적RRD환안여정상대조안mfERG、중심시야비교,수술전후황반구반응파N1、P1파진폭밀도강저、잠복기연장,MS치강저;여수술전mfERG、중심시야비교,수술후황반구반응파N1、P1파진폭밀도명현제고、잠복기축단,MS치제고.
    Objective To observe the changes of multifocal electroretinogram(mfERG)and central visual field before and after surgery in patients with rhegmatogenous retinal detachment (RRD) involving the macular area.Methods This is a retrospective study.Sixteen patients (16 eyes) with RRD involving the macular area (RRD group) and age-matched normal 20 cases (20 eyes,normal control group) were enrolled in the study.All patients in RRD group underwent scleral buckling surgery.Before surgery and 1,3,6 months after surgery,RRD eyes and normal eyes were checked by using mfERG and central visual field examination,and macular reaction wave amplitude density,incubation period and 4° visual field mean sensitivity (MS) were observed.The correlation between amplitude density,incubation period and MS in RRD group and the consistency between mfERG and central visual field examination in normal control group and RRD group were analyzed.Results Compared with the normal control group,in RRD group before surgery the macular reaction wave N1 and P1 amplitude density reduced,the incubation period prolonged,the differences were statistically significant (P＜ 0.05).Postoperative 1,3,6 months,in RRD group macular reaction wave amplitude density improved,the incubation period reduced than before surgery,the differences were statistically significant (P＜0.05).Postoperative 1,3,6 months,in RRD group macular reaction wave amplitude density reduced,the incubation period prolonged compared with the normal control group,the differences were statistically significant (P＜0.05).Compared with the normal control group,4° visual field MS significantly reduced in RRD group before surgery reduced,the differences were statistically significant (t=49.752,P＜0.05).Postoperative 1,3,6 months,4° visual field MS significantly increased compared with the preoperative value,the differences were statistically significant (t=-9.580,-16.533,-19.580; P＜ 0.05); but were lower than that of the normal control group,the differences were statistically significant (t =-6.286,-7.493,-6.366 ; P＜0.05).Postoperative 1,3,6 months,macular reaction wave amplitude density and MS in RRD group showed positive correlation (P＜0.05),and there was no correlation between incubation period and MS (P＞0.05).mfERG and vision consistency in normal control group and RRD group showed good agreement(K =0.886,P＜0.05).Conclusions Compared with normal control eyes,in RRD eyes involving the macula area before and after surgery,macular reaction wave amplitude density reduced,the incubation period prolonged and MS values reduced; compared with the preoperative mfERG and central visual field,macular reaction wave amplitude density improved,the incubation period reduced and MS values increased.
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