中华眼底病杂志
中華眼底病雜誌
중화안저병잡지
CHINESE JOURNAL OF OCULAR FUNDUS DISEASES
2014年
6期
574-577
,共4页
帕金森病/并发症%视野
帕金森病/併髮癥%視野
파금삼병/병발증%시야
Parkinson disease/complications%Visual fields
目的 观察轻度帕金森病(PD)患者视野光敏感度和视野缺损部位及形态的变化特点.方法 临床检查确诊的轻度PD患者33例66只眼(PD组)纳入研究.选取同期健康志愿者36名72只眼作为正常对照组.采用Humphrey-750全自动视野计对所有受检者行中心30-2视野检查,记录视野平均缺损(MD)值及模式标准差(PSD)值,青光眼半视野检测(GHT)结果;比较两组受检者局部及普遍光敏感度的强弱.结果 PD组、正常对照组平均MD值分别为(-3.4±2.5)、(-0.6±1.7)dB.两组平均MD值比较,差异有统计学意义(t=7.753 P=0.000);平均PSD值分别为(4.3±2.6)、(2.1±1.8) dB,两组平均PSD值比较,差异有统计学意义(t=5.882 P=0.000).PD组66只眼中,GHT处于正常界限以外31只眼;临界范围8只眼;正常范围内27只眼.视野正常27只眼,占40.9％;视野缺损39只眼,占59.1％.视野缺损的39只眼中,旁中心暗点16只眼,占视野缺损患眼的41.0％;鼻侧阶梯18只眼,占视野缺损患眼的46.2％;弓形暗点5只眼,占视野缺损患眼的12.8％.GHT处于正常范围以外的31眼中,旁中心暗点10只眼;鼻侧阶梯16只眼;弓形暗点5只眼.结论 轻度PD患者视野局部及普遍光敏感度明显下降;部分患眼出现视野上下方敏感度的差异和局限性视野缺损.
目的 觀察輕度帕金森病(PD)患者視野光敏感度和視野缺損部位及形態的變化特點.方法 臨床檢查確診的輕度PD患者33例66隻眼(PD組)納入研究.選取同期健康誌願者36名72隻眼作為正常對照組.採用Humphrey-750全自動視野計對所有受檢者行中心30-2視野檢查,記錄視野平均缺損(MD)值及模式標準差(PSD)值,青光眼半視野檢測(GHT)結果;比較兩組受檢者跼部及普遍光敏感度的彊弱.結果 PD組、正常對照組平均MD值分彆為(-3.4±2.5)、(-0.6±1.7)dB.兩組平均MD值比較,差異有統計學意義(t=7.753 P=0.000);平均PSD值分彆為(4.3±2.6)、(2.1±1.8) dB,兩組平均PSD值比較,差異有統計學意義(t=5.882 P=0.000).PD組66隻眼中,GHT處于正常界限以外31隻眼;臨界範圍8隻眼;正常範圍內27隻眼.視野正常27隻眼,佔40.9％;視野缺損39隻眼,佔59.1％.視野缺損的39隻眼中,徬中心暗點16隻眼,佔視野缺損患眼的41.0％;鼻側階梯18隻眼,佔視野缺損患眼的46.2％;弓形暗點5隻眼,佔視野缺損患眼的12.8％.GHT處于正常範圍以外的31眼中,徬中心暗點10隻眼;鼻側階梯16隻眼;弓形暗點5隻眼.結論 輕度PD患者視野跼部及普遍光敏感度明顯下降;部分患眼齣現視野上下方敏感度的差異和跼限性視野缺損.
목적 관찰경도파금삼병(PD)환자시야광민감도화시야결손부위급형태적변화특점.방법 림상검사학진적경도PD환자33례66지안(PD조)납입연구.선취동기건강지원자36명72지안작위정상대조조.채용Humphrey-750전자동시야계대소유수검자행중심30-2시야검사,기록시야평균결손(MD)치급모식표준차(PSD)치,청광안반시야검측(GHT)결과;비교량조수검자국부급보편광민감도적강약.결과 PD조、정상대조조평균MD치분별위(-3.4±2.5)、(-0.6±1.7)dB.량조평균MD치비교,차이유통계학의의(t=7.753 P=0.000);평균PSD치분별위(4.3±2.6)、(2.1±1.8) dB,량조평균PSD치비교,차이유통계학의의(t=5.882 P=0.000).PD조66지안중,GHT처우정상계한이외31지안;림계범위8지안;정상범위내27지안.시야정상27지안,점40.9％;시야결손39지안,점59.1％.시야결손적39지안중,방중심암점16지안,점시야결손환안적41.0％;비측계제18지안,점시야결손환안적46.2％;궁형암점5지안,점시야결손환안적12.8％.GHT처우정상범위이외적31안중,방중심암점10지안;비측계제16지안;궁형암점5지안.결론 경도PD환자시야국부급보편광민감도명현하강;부분환안출현시야상하방민감도적차이화국한성시야결손.
Objective To evaluate visual field changes in early mild Parkinson's disease.Methods A total of 66 eyes of 33 cases with early mild Parkinson's disease and 72 eyes of 36 age-matched normal individuals were enrolled into the study.Humphrey Field Analyzer Ⅱ was applied for central visual field test.The visual field indices of mean deviation (MD) and pattern standard deviation (PSD) were analyzed to evaluate the location and the characteristics of visual field defect in this study.Results Visual field indices MD (-3.4±2.5) dB was significantly changed in patients with PD when compared to the controls (-0.6 ± 1.7) dB.PSD (4.3±2.6) was significantly higher in patients with PD than that in the control group (2.1 ± 1.8) dB.Glaucoma hemifield test (GHT) assessment was within normal limits in the controls.Of the 33 patients (66 eyes) in PD,GHT showed outside normal limits in 31 eyes,borderline in 8 eyes,and within normal limits in 27 eyes.31 eyes outside normal limits appeared glaucomatous visual field defects,in which 16 with nasal step and 5 with arcuate defect.Conclusions Visual field indices including MD and PSD in early mild patients with PD were significantly worse than that in the controls group.GHT abnormalities could be found in early mild PD patients with visual field defects,including pericentral scotoma and nasal step,which mimicked glaucomatous changes.
