CAJ | 학술논문

目的调查异位妊娠发生的相关危险因素,为进一步预防及减少异位妊娠的发病提供科学依据.方法对2010年6月至2011年12月在上海市三家医院确诊为异位妊娠的800例住院患者,通过问卷调查的方式,了解异位妊娠的相关发病因素.并随机选取700例同期正常早期妊娠者作为对照组,采集相关临床资料分别进行单因素、多因素回归分析,筛选出异位妊娠发病的高危因素.结果 800例中年龄≤25岁175例,占25.5％;26—30岁302例,占37.8％;31～ 35岁213例,占26.6％;无避孕措施259例,占32.4％;异位妊娠发生的相关危险因素包括口服紧急避孕药、宫内节育器、盆腔炎症、不孕症病史、前次异位妊娠、吸烟及年龄等.多因素Logistic逐步回归分析筛选结果,OR值由大到小依次为:不孕症、异位妊娠史、吸烟史、紧急避孕药服用、宫内节育器(IUD)、盆腔炎性疾病、年龄.结论异位妊娠的发病风险受多种因素影响,不孕症、异位妊娠史、吸烟史、紧急避孕药服用、异位妊娠史、IUD(宫内节育器)、盆腔炎性疾病、年龄等是异位妊娠发病的高危因素,应引起临床重视.
목적 조사이위임신발생적상관위험인소,위진일보예방급감소이위임신적발병제공과학의거.방법 대2010년6월지2011년12월재상해시삼가의원학진위이위임신적800례주원환자,통과문권조사적방식,료해이위임신적상관발병인소.병수궤선취700례동기정상조기임신자작위대조조,채집상관림상자료분별진행단인소、다인소회귀분석,사선출이위임신발병적고위인소.결과 800례중년령≤25세175례,점25.5％;26—30세302례,점37.8％;31～ 35세213례,점26.6％;무피잉조시259례,점32.4％;이위임신발생적상관위험인소포괄구복긴급피잉약、궁내절육기、분강염증、불잉증병사、전차이위임신、흡연급년령등.다인소Logistic축보회귀분석사선결과,OR치유대도소의차위:불잉증、이위임신사、흡연사、긴급피잉약복용、궁내절육기(IUD)、분강염성질병、년령.결론 이위임신적발병풍험수다충인소영향,불잉증、이위임신사、흡연사、긴급피잉약복용、이위임신사、IUD(궁내절육기)、분강염성질병、년령등시이위임신발병적고위인소,응인기림상중시.
Objective To conduct an epidemiological survey on the relevant risk factors of ectopic pregnancy (EP) and provide scientific rationales for prevention and reducing its incidence.Methods During June 2010 to December 2011 at three local hospitals,a total of 800 patients with a diagnosis of EP responded to a questionnaire survey for understanding the risk factors of EP.And another 700 cases of normal early pregnancy women were selected as control group.Both multi and uni-factorial regression analyses were performed for the acquired clinical data.And the high-risk factors of EP were screened.Results Among them,the age distribution was ≤ 25 years (n =175,25.5％),26-30 years (n =302,37.8％) and 31-35 years (n =213,26.6％).No contraceptive measure was adopted for 259 women (32.4％).The risk factors related to EP included oral emergency contraceptives,intrauterine device (IUD),pelvic inflammatory disease,infertility history,previous EP,smoking and age,etc.Based upon multivariate Logistic regression analysis of screening results,the decreasing odds rations were infertility,EP history,smoking history,emergency contraceptive use,history of EP,IUD,pelvic inflammatory disease and age.Conclusion The risks of EP are affected by many factors,including infertility,EP history,smoking history,emergency contraceptive use,history of EP,IUD,pelvic inflammatory disease and age.