中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
4期
7-9
,共3页
重症肺炎%无创正压通气%预后分析
重癥肺炎%無創正壓通氣%預後分析
중증폐염%무창정압통기%예후분석
Severe pneumonia%Noninvasive positive pressure ventilation%Prognosis analysis
目的 探讨无创正压通气治疗重症肺炎的临床疗效.方法 将100例重症肺炎患者在征得患者家属同意的前提下随机分为两组,所有患者均行常规治疗如抗感染、祛痰等,针对基础疾病和并发症治疗,观察组应用无创正压机械通气,对照组给予鼻导管吸氧,观察对比两组患者的治疗预后.结果 治疗前两组各项动脉血气分析指标比较差异未见统计学意义(P>0.05),治疗后两组pH和Pa02值均较治疗前明显升高,差异有统计学意义(P<0.05),PaCO2值较治疗前明显下降,差异有统计学意义(P<0.O5);观察组治疗后在改善PaCO2和PaO2值方面明显优于对照组,差异有统计学意义(P<0.05).观察组和对照组临床总有效率分别为94.00%,76.00%,观察组明显高于对照组,差异有统计学意义(x2=4.373,P<0.05).观察组3例(6.00%)患者因病情恶化改有创机械通气,对照组14例(28.00%)改有创机械通气,两组比较差异有统计学意义(P<0.05);观察组平均住院时间为(12.57±5.30)d,显著少于对照组的(21.48±6.30)d,差异有统计学意义(P<0.05);观察组1例(2%)因抢救无效死亡,对照组死亡3例(6%),两组比较差异未见统计学意义(P>0.05).结论 无创正压通气在临床应用效果满意,临床效果优于单纯应用鼻导管吸氧的方式,在有条件的医院应推广应用.
目的 探討無創正壓通氣治療重癥肺炎的臨床療效.方法 將100例重癥肺炎患者在徵得患者傢屬同意的前提下隨機分為兩組,所有患者均行常規治療如抗感染、祛痰等,針對基礎疾病和併髮癥治療,觀察組應用無創正壓機械通氣,對照組給予鼻導管吸氧,觀察對比兩組患者的治療預後.結果 治療前兩組各項動脈血氣分析指標比較差異未見統計學意義(P>0.05),治療後兩組pH和Pa02值均較治療前明顯升高,差異有統計學意義(P<0.05),PaCO2值較治療前明顯下降,差異有統計學意義(P<0.O5);觀察組治療後在改善PaCO2和PaO2值方麵明顯優于對照組,差異有統計學意義(P<0.05).觀察組和對照組臨床總有效率分彆為94.00%,76.00%,觀察組明顯高于對照組,差異有統計學意義(x2=4.373,P<0.05).觀察組3例(6.00%)患者因病情噁化改有創機械通氣,對照組14例(28.00%)改有創機械通氣,兩組比較差異有統計學意義(P<0.05);觀察組平均住院時間為(12.57±5.30)d,顯著少于對照組的(21.48±6.30)d,差異有統計學意義(P<0.05);觀察組1例(2%)因搶救無效死亡,對照組死亡3例(6%),兩組比較差異未見統計學意義(P>0.05).結論 無創正壓通氣在臨床應用效果滿意,臨床效果優于單純應用鼻導管吸氧的方式,在有條件的醫院應推廣應用.
목적 탐토무창정압통기치료중증폐염적림상료효.방법 장100례중증폐염환자재정득환자가속동의적전제하수궤분위량조,소유환자균행상규치료여항감염、거담등,침대기출질병화병발증치료,관찰조응용무창정압궤계통기,대조조급여비도관흡양,관찰대비량조환자적치료예후.결과 치료전량조각항동맥혈기분석지표비교차이미견통계학의의(P>0.05),치료후량조pH화Pa02치균교치료전명현승고,차이유통계학의의(P<0.05),PaCO2치교치료전명현하강,차이유통계학의의(P<0.O5);관찰조치료후재개선PaCO2화PaO2치방면명현우우대조조,차이유통계학의의(P<0.05).관찰조화대조조림상총유효솔분별위94.00%,76.00%,관찰조명현고우대조조,차이유통계학의의(x2=4.373,P<0.05).관찰조3례(6.00%)환자인병정악화개유창궤계통기,대조조14례(28.00%)개유창궤계통기,량조비교차이유통계학의의(P<0.05);관찰조평균주원시간위(12.57±5.30)d,현저소우대조조적(21.48±6.30)d,차이유통계학의의(P<0.05);관찰조1례(2%)인창구무효사망,대조조사망3례(6%),량조비교차이미견통계학의의(P>0.05).결론 무창정압통기재림상응용효과만의,림상효과우우단순응용비도관흡양적방식,재유조건적의원응추엄응용.
Objective To study the clinical curative effects of noninvasive positive pressure ventilation (NPPV) on severe pneumonia.Mcthods One hundred cases of severe pneumonia (SP) in the premise of patient consent were randomly divided into two groups.All patients received routine treatment such as anti infective,phlegm,for the underlying diseases and complications of the treatment,and on this basis the patients in observation group recieved noninvasive positive pressure ventilation (NPPV) treatment,the patients in control group treated with nasal catheter observation of oxygen.The prognosis of the two groups was compared.Results There was no significant difference in arterial blood gas index between the two groups before treatment (P > 0.05),the pH and PaO2 values were significantly higher than that before treatment,and the differences were statistically significant (P < 0.05).PaCO2 values were significantly decreased than that before treatment,and the difference was statistically significant (P < 0.05) ; the PaCO2 and PaO2 improvement were obviously in the observation group better than the control group,with statistical significance (P < 0.05).The total clinical effective rates were 94% and 76% of observation group and control group,and the difference was statistically significant (x2 =4.373,P < 0.05).In the observation group,3 cases (6%) had invasive mechanical ventilation because of disease progression,and 14 cases in the control group (28%) had invasive mechanical ventilation,there was significant difference (P < 0.05).In observation group,the average hospitalization time was (12.57 ±5.30)d,and that in the control group was (21.48 ± 6.30)d,there was significant difference (P <0.05).One case (2%) died in the observation group,and 3 cases died in the control group (6%),there was no significant difference between the two groups (P > 0.05).Conclusions The clinical effect of noninvasive positive pressure ventilation (NPPV) is satisfactory,and the clinical effect is better than the simple application of nasal catheter oxygen manner,so it should be popularized and applied.