中国实用医刊
中國實用醫刊
중국실용의간
CENTRAL PLAINS MEDICAL JOURNAL
2015年
4期
10-12
,共3页
血必净%心肺复苏%继发性脑损伤%S-100β蛋白%神经元特异性烯醇化酶
血必淨%心肺複囌%繼髮性腦損傷%S-100β蛋白%神經元特異性烯醇化酶
혈필정%심폐복소%계발성뇌손상%S-100β단백%신경원특이성희순화매
Xuebijing%Cardiopulmonary resuscitation (CPR)%Secondary brain injury%S100βprotein%Neuron specific enolase (NSE)
目的 观察血必净治疗心肺复苏后继发性脑损伤的临床疗效.方法 选择心肺复苏术后患者31例,按随机数字表法分为常规治疗组15例和血必净组16例.两组患者入院后均给予常规治疗,血必净组在常规治疗的基础上加用血必净治疗7d.比较两组患者心肺复苏后第1、3、5、7天血清S-100β蛋白和NSE的水平及格拉斯哥昏迷评分(GCS)评分.结果 与常规治疗组相比,血必净组血清S-100β蛋白和NSE水平在心肺复苏后各时间点均明显降低(P＜0.05),第5、7天GCS评分明显增高(P＜0.05).结论 血必净能降低心肺复苏术后患者血清S-100β蛋白和NSE的水平,减轻心肺复苏后的继发性脑损伤,改善脑功能.
目的 觀察血必淨治療心肺複囌後繼髮性腦損傷的臨床療效.方法 選擇心肺複囌術後患者31例,按隨機數字錶法分為常規治療組15例和血必淨組16例.兩組患者入院後均給予常規治療,血必淨組在常規治療的基礎上加用血必淨治療7d.比較兩組患者心肺複囌後第1、3、5、7天血清S-100β蛋白和NSE的水平及格拉斯哥昏迷評分(GCS)評分.結果 與常規治療組相比,血必淨組血清S-100β蛋白和NSE水平在心肺複囌後各時間點均明顯降低(P＜0.05),第5、7天GCS評分明顯增高(P＜0.05).結論 血必淨能降低心肺複囌術後患者血清S-100β蛋白和NSE的水平,減輕心肺複囌後的繼髮性腦損傷,改善腦功能.
목적 관찰혈필정치료심폐복소후계발성뇌손상적림상료효.방법 선택심폐복소술후환자31례,안수궤수자표법분위상규치료조15례화혈필정조16례.량조환자입원후균급여상규치료,혈필정조재상규치료적기출상가용혈필정치료7d.비교량조환자심폐복소후제1、3、5、7천혈청S-100β단백화NSE적수평급격랍사가혼미평분(GCS)평분.결과 여상규치료조상비,혈필정조혈청S-100β단백화NSE수평재심폐복소후각시간점균명현강저(P＜0.05),제5、7천GCS평분명현증고(P＜0.05).결론 혈필정능강저심폐복소술후환자혈청S-100β단백화NSE적수평,감경심폐복소후적계발성뇌손상,개선뇌공능.
Objective To evaluate the curative effect of Xuebijing on secondary brain injury after cardiopulmonary resuscitation(CPR).Methods Thirty-one patients after CPR were randomly divided into the conventional treatment group (15 cases) and Xuebijing group (16 cases).Two groups were given conventional treatment;while in the Xuebijing group,Xuebijing injection was additionally given for consecutive 7 days.The serum S-100β protein and NSE levels and Glasgow Coma Scale(GCS) score at 1,3,5,7 days after CPR were compared.Results The serum S-100β protein and NSE levels were significantly lower in the Xuebijing group at 1,3,5,7 days after CPR(P ＜0.05) ; Compared with the Conventional treatment group,GCS score was significantly higher in the Xuebijing group at 5,7 days after CPR(P ＜0.05).Conclusions Xuebijing can reduce the serum S-100β protein and NSE level in patients after CPR,and alleviate secondary brain injury after CPR,improving brain function.
