CAJ | 학술논문

目的探讨多囊卵巢综合征患者内分泌及代谢的临床特征.方法将64例多囊卵巢综合征患者按照是否肥胖分成两组,肥胖组36例,非肥胖组28例.为了使研究更具有说服性,选择正常人25例作为对照组.对这三组进行胰岛素释放试验,同时还需要对患者进行口服葡萄糖耐量试验.随后对这三组分别进行血脂、血压、性激素以及体质量指数测定,并对胰岛素的敏感指数进行计算.结果肥胖组与非肥胖组及对照组相比,肥胖组体质量指数、收缩压、低密度脂蛋白-胆固醇以及三酰甘油显著降低,差异有统计学意义(P＜0.05).肥胖组、非肥胖组与对照组相比睾酮及空腹胰岛素水平显著升高,胰岛素敏感指数降低.结论多囊卵巢综合征患者内分泌及代谢特征在一定程度上处于紊乱状态,特别是对于肥胖患者更是严重.
목적 탐토다낭란소종합정환자내분비급대사적림상특정.방법 장64례다낭란소종합정환자안조시부비반분성량조,비반조36례,비비반조28례.위료사연구경구유설복성,선택정상인25례작위대조조.대저삼조진행이도소석방시험,동시환수요대환자진행구복포도당내량시험.수후대저삼조분별진행혈지、혈압、성격소이급체질량지수측정,병대이도소적민감지수진행계산.결과 비반조여비비반조급대조조상비,비반조체질량지수、수축압、저밀도지단백-담고순이급삼선감유현저강저,차이유통계학의의(P＜0.05).비반조、비비반조여대조조상비고동급공복이도소수평현저승고,이도소민감지수강저.결론 다낭란소종합정환자내분비급대사특정재일정정도상처우문란상태,특별시대우비반환자경시엄중.
Objective To investigate the clinical features of endocrine and metabolism in patients with polycystic ovary syndrome.Methods Patients with polycystic ovary syndrome were divided into two groups according to obese or not,obese group (36 cases) and non-obese group (28 cases).In order to make research more persuasive,25 cases of normal people were selected as control group.These three groups were tested by insulin release,while the patients needs an oral glucose tolerance test.Then the blood lipids,blood pressure,and body mass index were measured sex hormones,and insulin sensitivity index was calculated.Results Compared with the control group,the BMI,systolic blood pressure,LDL-cholesterol and triglycerides of the obese group was significantly reduced.Obese,non-obese group compared with the control group,two groups patients underwent gall bladder before the emergence of testosterone significantly increased.In addition,and in the control group compared to the situation before the fasting insulin measured in both groups appeared significantly increased.The insulin sensitivity index appeared lowering in a certain degree.Conclusions There is some extent in the disordered state in the patients with polycystic ovary syndrome on endocrine and metabolic characteristics,especially for the obese patients,it is serious.