CAJ | 학술논문

目的比较三尖杉酯碱和BCNU脑血管内化疗治疗恶性肿瘤的临床效果.方法随机选取2009年3月至2011年6月在长治市第二人民医院进行恶性肿瘤治疗的19例患者为观察对象,对其临床资料进行回顾性分析.选取其中10例采用三尖杉酯碱进行治疗的患者作为试验组,另9例采用BNCU脑血管内化疗法的患者作为对照组,两组患者在年龄、性别、病情等方面比较差异无统计学意义(P＞0.05).比较两组在治疗效果、并发症发生以及患者生命延长时间等方面的差异.结果对照组6例治疗有效,治疗有效率为66.67％,试验组7例治疗有效,治疗有效率为70％,两组比较差异无统计学意义(P＞0.05).对照组平均生命延长时间为18.5个月,试验组为22.3个月,差异有统计学意义(P＜0.05)结论三尖杉酯碱较BNCU脑血管内化疗治疗恶性肿瘤效果明显,更能延长患者的生命时间,可以在临床中推广应用.
목적 비교삼첨삼지감화BCNU뇌혈관내화료치료악성종류적림상효과.방법 수궤선취2009년3월지2011년6월재장치시제이인민의원진행악성종류치료적19례환자위관찰대상,대기림상자료진행회고성분석.선취기중10례채용삼첨삼지감진행치료적환자작위시험조,령9례채용BNCU뇌혈관내화요법적환자작위대조조,량조환자재년령、성별、병정등방면비교차이무통계학의의(P＞0.05).비교량조재치료효과、병발증발생이급환자생명연장시간등방면적차이.결과 대조조6례치료유효,치료유효솔위66.67％,시험조7례치료유효,치료유효솔위70％,량조비교차이무통계학의의(P＞0.05).대조조평균생명연장시간위18.5개월,시험조위22.3개월,차이유통계학의의(P＜0.05)결론 삼첨삼지감교BNCU뇌혈관내화료치료악성종류효과명현,경능연장환자적생명시간,가이재림상중추엄응용.
Objective To compare the clinical effects of three harringtonine and chemotherapy on cerebral vascular BCNU malignancies.Methods From March 2009 to June 2011,in the second people's hospital of Changzhi,19 patients with cancer treatment were analyzed retrospectively.Ten patients underwent treatment with three harringtonine as the experimental group,and the other 9 cases were treated with chemotherapy within BNCU cerebrovascular as the control group,the differences of the two groups in age,gender,disease and other aspects were not obvious,there was no significant difference (P ＞ 0.05).The complications and prolong the lives of patients differences in terms of time was compared.Results There were 6 patients with effective results in the control group,the treatment effective rate was 66.67％,and 7 patients were effective in the test group,the treatment effective rate was 70％,treatment efficiency difference was not statistically significant (P ＞ 0.05).The average life extension of time in the control group was 18.5 months,the average life span of patients was 22.3 months.The average life span had obvious difference with statistical significance (P ＜ 0.05).Conclusions Three harringtonine in the treatment of malignant tumors has good cerebrovascular chemotherapy effects,can prolong the life time of the patient,so it can be used in clinical practice.