国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2014年
24期
1905-1908
,共4页
肺癌%肿瘤转移%炎症微环境
肺癌%腫瘤轉移%炎癥微環境
폐암%종류전이%염증미배경
Lung cancer%Tumor metastasis%Inflammatory microenvironment
近年来,炎症微环境在肿瘤进展过程中的作用日益受到重视,多项研究表明肺癌的炎症微环境在肺癌的转移中起着重要作用.炎症微环境可以通过直接或间接促进肿瘤血管生成、细胞增殖和抑制细胞凋亡进程,从而促进肺癌的转移,而这一过程主要是借助炎症因子、炎症信号通路等途径而实现的.本文就近年来肺癌转移的炎症微环境机制相关的研究进展作一综述.
近年來,炎癥微環境在腫瘤進展過程中的作用日益受到重視,多項研究錶明肺癌的炎癥微環境在肺癌的轉移中起著重要作用.炎癥微環境可以通過直接或間接促進腫瘤血管生成、細胞增殖和抑製細胞凋亡進程,從而促進肺癌的轉移,而這一過程主要是藉助炎癥因子、炎癥信號通路等途徑而實現的.本文就近年來肺癌轉移的炎癥微環境機製相關的研究進展作一綜述.
근년래,염증미배경재종류진전과정중적작용일익수도중시,다항연구표명폐암적염증미배경재폐암적전이중기착중요작용.염증미배경가이통과직접혹간접촉진종류혈관생성、세포증식화억제세포조망진정,종이촉진폐암적전이,이저일과정주요시차조염증인자、염증신호통로등도경이실현적.본문취근년래폐암전이적염증미배경궤제상관적연구진전작일종술.
In recent years,more and more attention has been paid to the effect of inflammatory microenvironment on tumor metastasis,and several studies have shown that inflammatory microenvironment plays an important role in metastasis of lung cancer.Inflammatory microenvironment could promote tumor to migrate via facilitating angiogenesis and proliferation,or inhibiting apoptosis both directly and indirectly,mediated by inflammatory factors and inflammatory signal pathways.This artide reviews some research progress in inflammatory microenvironment mechanism of lung cancer metastasis.