中国医师杂志
中國醫師雜誌
중국의사잡지
JOURNAL OF CHINESE PHYSICIAN
2014年
12期
1614-1616,1620
,共4页
右美托咪啶/治疗应用%二异丙酚/治疗应用%舒芬太尼/治疗应用%脊柱侧凸/外科学%麻醉
右美託咪啶/治療應用%二異丙酚/治療應用%舒芬太尼/治療應用%脊柱側凸/外科學%痳醉
우미탁미정/치료응용%이이병분/치료응용%서분태니/치료응용%척주측철/외과학%마취
Dexmedetomidine/therapeutic use%Propofol/therapeutic use%Sufentanil/therapeutic use%Scoliosis/surgery%Anesthesia
目的 观察右美托咪定辅助靶控丙泊酚-舒芬太尼麻醉用于脊柱侧弯矫形术的安全性和有效性.方法 择期行脊柱侧弯矫形术患者40例,按随机数字表法分为右美托咪定组(D组)和生理盐水组(C组),每组20例,分别在麻醉诱导前给予0.8 μg/kg右美托咪定和等量生理盐水,10 min输完.术中D组持续泵入右美托咪定0.2μg/(kg·h),C组输注等容量生理盐水.观察麻醉诱导前10 min(T1)、麻醉诱导后3 min(T2)、气管插管后1 min(T3)、停药(T4)、唤醒即刻(T5)、加深麻醉后6 min(T6)的收缩压(SBP)、舒张压(DBP)、心率(HR).记录两组血液动力学、唤醒时间、唤醒成功率、唤醒期间的躁动情况及唤醒期间的出血量,记录有无术中知晓.结果 两组唤醒成功率比较差异无统计学意义(P>0.05),D组较C组血液动力学稳定(P<0.05),D组躁动的发生率及唤醒期间的出血量显著少于C组(P<0.05).结论 右美托咪定辅助靶控丙泊酚-舒芬太尼麻醉能有效实施术中唤醒,有助于减少唤醒期间的出血量及躁动的发生,使术中血流动力学更平稳.
目的 觀察右美託咪定輔助靶控丙泊酚-舒芬太尼痳醉用于脊柱側彎矯形術的安全性和有效性.方法 擇期行脊柱側彎矯形術患者40例,按隨機數字錶法分為右美託咪定組(D組)和生理鹽水組(C組),每組20例,分彆在痳醉誘導前給予0.8 μg/kg右美託咪定和等量生理鹽水,10 min輸完.術中D組持續泵入右美託咪定0.2μg/(kg·h),C組輸註等容量生理鹽水.觀察痳醉誘導前10 min(T1)、痳醉誘導後3 min(T2)、氣管插管後1 min(T3)、停藥(T4)、喚醒即刻(T5)、加深痳醉後6 min(T6)的收縮壓(SBP)、舒張壓(DBP)、心率(HR).記錄兩組血液動力學、喚醒時間、喚醒成功率、喚醒期間的躁動情況及喚醒期間的齣血量,記錄有無術中知曉.結果 兩組喚醒成功率比較差異無統計學意義(P>0.05),D組較C組血液動力學穩定(P<0.05),D組躁動的髮生率及喚醒期間的齣血量顯著少于C組(P<0.05).結論 右美託咪定輔助靶控丙泊酚-舒芬太尼痳醉能有效實施術中喚醒,有助于減少喚醒期間的齣血量及躁動的髮生,使術中血流動力學更平穩.
목적 관찰우미탁미정보조파공병박분-서분태니마취용우척주측만교형술적안전성화유효성.방법 택기행척주측만교형술환자40례,안수궤수자표법분위우미탁미정조(D조)화생리염수조(C조),매조20례,분별재마취유도전급여0.8 μg/kg우미탁미정화등량생리염수,10 min수완.술중D조지속빙입우미탁미정0.2μg/(kg·h),C조수주등용량생리염수.관찰마취유도전10 min(T1)、마취유도후3 min(T2)、기관삽관후1 min(T3)、정약(T4)、환성즉각(T5)、가심마취후6 min(T6)적수축압(SBP)、서장압(DBP)、심솔(HR).기록량조혈액동역학、환성시간、환성성공솔、환성기간적조동정황급환성기간적출혈량,기록유무술중지효.결과 량조환성성공솔비교차이무통계학의의(P>0.05),D조교C조혈액동역학은정(P<0.05),D조조동적발생솔급환성기간적출혈량현저소우C조(P<0.05).결론 우미탁미정보조파공병박분-서분태니마취능유효실시술중환성,유조우감소환성기간적출혈량급조동적발생,사술중혈류동역학경평은.
Objective To investigate effect of dexmedetomidine on safety,validity and superiority in patients undergoing scoliosis surgery under propofol sufentanil anesthesia.Methods Forty patients undcrgoing elective posterior scoliosis surgery were randomly divided into groups D and C (n =10 each).Dexmedetomidine 0.8 μg/kg followed by 0.2 μg/(kg · h) and equal volume were infused at the 10 min before anesthesia induction in two groups,respectively.Hemodynamic parameters were observed at the 10 min before anesthesia induction (T1),3 min (T2) after anesthesia induction,1 min (T3) after intubation,at the beginning of wake-up test (T4),at the end of the test (T5),and 6 min (T6) after deepen anesthesia,respectively.Meanwhile the wake-up time,hemodynamic parameters,success rate of arousal,incidence agitation,and the bleeding volume during the test were also recorded.Results Successive rate of arousal awakening time between two groups had no statistical significance (P > 0.05).Less incidence of agitation was found in group D compared to group C (P < 0.05).The bleeding volume during the test was significantly less in group D (P < 0.05).The hemodynamics was more smoothly during the operation in group D compared to group C (P < 0.05).Conclusions Dexmedetomidine auxiliary propofol and sufentanil anesthesia can effectively implement intraoperative wake-up,reduce the amount of bleeding,and the incidence of agitation during the wake-up.The hemodynamics was more smoothly.