国际呼吸杂志
國際呼吸雜誌
국제호흡잡지
INTERNATIONAL JOURNAL OF RESPIRATION
2014年
24期
1875-1878
,共4页
血栓栓塞性疾病,血管性血友病因子裂解蛋白酶%血管性血友病因子
血栓栓塞性疾病,血管性血友病因子裂解蛋白酶%血管性血友病因子
혈전전새성질병,혈관성혈우병인자렬해단백매%혈관성혈우병인자
Thromboembolism%Von Willebrand factor-cleaving protease%Von Willebrand factor
血栓栓塞性疾病包含动脉血栓栓塞性疾病、静脉血栓栓塞性疾病及微血管血栓栓塞(如弥漫性血管内凝血、血栓性血小板减少性紫癜).许多研究表明,血栓栓塞性疾病与血管性血友病因子裂解酶(即ADAMTS-13)活性的改变有着密切的关系.ADAMTS13主要由血管内皮细胞、肝脏星状细胞、骨骼肌细胞等细胞合成和分泌.本文就血栓栓塞性疾病与ADAMTS-13相关性方面的研究进展作一综述.
血栓栓塞性疾病包含動脈血栓栓塞性疾病、靜脈血栓栓塞性疾病及微血管血栓栓塞(如瀰漫性血管內凝血、血栓性血小闆減少性紫癜).許多研究錶明,血栓栓塞性疾病與血管性血友病因子裂解酶(即ADAMTS-13)活性的改變有著密切的關繫.ADAMTS13主要由血管內皮細胞、肝髒星狀細胞、骨骼肌細胞等細胞閤成和分泌.本文就血栓栓塞性疾病與ADAMTS-13相關性方麵的研究進展作一綜述.
혈전전새성질병포함동맥혈전전새성질병、정맥혈전전새성질병급미혈관혈전전새(여미만성혈관내응혈、혈전성혈소판감소성자전).허다연구표명,혈전전새성질병여혈관성혈우병인자렬해매(즉ADAMTS-13)활성적개변유착밀절적관계.ADAMTS13주요유혈관내피세포、간장성상세포、골격기세포등세포합성화분비.본문취혈전전새성질병여ADAMTS-13상관성방면적연구진전작일종술.
Thromboembolism encompasses arterial thromboembolism,venous thromboembolism,and microvascular thromboembolism such as disseminated intravascular coagulation,thrombotic thrombocytopenic purpura.Many studies show that there is close association between thromboembolism and change on activity of yon Willebrand factor-cleaving protease (ADAMTS-13).ADAMTS-13 is synthesized and secreted by vascular endothelial cells,hepatic stellate cells,and other cells.This paper is aimed to review progress of the association between thromboembolism and ADAMTS-13.
