CAJ | 학술논문

网状假性玻璃膜疣(RPD)多发于中老年视网膜变性患者,表现为直径125 ～ 250 μm的圆形或椭圆形黄色网状图形病变,易与典型的玻璃膜疣混淆.大量的临床观察证实RPD在眼底分布、形态特征、发展特点等方面,均具有与典型玻璃膜疣不同的特征,提示两者可能具有不同的病理生理学基础.联合使用多种眼底影像检查手段,有助于提高RPD的诊断率.研究表明RPD与AMD的高风险因素有关,同时也是脉络膜新生血管和RPE地图样萎缩的高风险因素,但在息肉状脉络膜血管病变患者中很少发现RPD.准确识别RPD有助于诊断、治疗眼底疾病和判断预后,因此鉴别RPD和玻璃膜疣以及对RPD患者进行长期密切随访观察尤为必要.
망상가성파리막우(RPD)다발우중노년시망막변성환자,표현위직경125 ～ 250 μm적원형혹타원형황색망상도형병변,역여전형적파리막우혼효.대량적림상관찰증실RPD재안저분포、형태특정、발전특점등방면,균구유여전형파리막우불동적특정,제시량자가능구유불동적병리생이학기출.연합사용다충안저영상검사수단,유조우제고RPD적진단솔.연구표명RPD여AMD적고풍험인소유관,동시야시맥락막신생혈관화RPE지도양위축적고풍험인소,단재식육상맥락막혈관병변환자중흔소발현RPD.준학식별RPD유조우진단、치료안저질병화판단예후,인차감별RPD화파리막우이급대RPD환자진행장기밀절수방관찰우위필요.
Reticular pseudodrusen (RPD) has recently been identified as a particular yellowish interlacing network of oval or round lesion in the fundus of aged retinal degeneration patients.RPD can be easily misdiagnosed as typical drusen.However,a large number of observations indicated that RPD and typical drusen are different in distribution,morphological features and pathophysiological processes.The diagnosis of RPD relies on multiple fundus examinations including fundus autofluorescence,infrared reflectance and spectral-domain optical coherence tomography.RPD may be associated with age-related macular degeneration,choroidal neovascularization and geographic atrophy,but the prevalence of RPD is found low in polypoidalchoroidalvasculopathycases.Differential diagnosis of RPD and drusen may affect the treatment and prognosis of these conditions.Thus a careful long-term follow-up is mandatory for these patients.