中华流行病学杂志
中華流行病學雜誌
중화류행병학잡지
CHINESE JOURNAL OF EPIDEMIOLOGY
2015年
1期
40-44
,共5页
邢爱君%季春鹏%施继红%杜鑫%黄喆%林黎明%熊海亮%吴寿岭
邢愛君%季春鵬%施繼紅%杜鑫%黃喆%林黎明%熊海亮%吳壽嶺
형애군%계춘붕%시계홍%두흠%황철%림려명%웅해량%오수령
非酒精性脂肪肝%理想心血管健康行为和因素%患病率
非酒精性脂肪肝%理想心血管健康行為和因素%患病率
비주정성지방간%이상심혈관건강행위화인소%환병솔
Nonalcoholic fatty liver disease%Ideal cardiovascular behaviors and factors%Prevalence
目的 探讨理想心血管健康行为和因素与非酒精性脂肪肝(NAFLD)的关系.方法 以参加2006-2007年度健康体检的101 510名开滦集团公司职工为研究对象,排除饮酒者、心肌梗死、脑卒中、恶性肿瘤以及资料不全者,最终纳入54 303例,观察研究人群中NAFLD的患病情况.根据美国心脏协会定义的理想心血管健康行为和因素,采用多因素logistic回归模型分析理想心血管健康行为和因素与NAFLD的关系.结果 具备0～1、2、3、4、5～7个理想心血管健康行为和因素组的NAFLD患病率分别为62.6％、48.9％、33.3％、16.1％和7.5％ (P＜0.000 1).校正年龄、性别、经济收入水平、文化程度等混杂因素后,理想心血管健康行为和因素与NAFLD有关,且随着健康行为和因素个数的增多(0～1、2、3、4、5～7),OR值(95％CI)逐渐降低,分别为1、0.61(0.56～0.66)、0.37(0.34～0.40)、0.17(0.15 ～0.18)和0.08(0.07 ～0.09).结论 理想心血管健康行为和因素与NAFLD相关.
目的 探討理想心血管健康行為和因素與非酒精性脂肪肝(NAFLD)的關繫.方法 以參加2006-2007年度健康體檢的101 510名開灤集糰公司職工為研究對象,排除飲酒者、心肌梗死、腦卒中、噁性腫瘤以及資料不全者,最終納入54 303例,觀察研究人群中NAFLD的患病情況.根據美國心髒協會定義的理想心血管健康行為和因素,採用多因素logistic迴歸模型分析理想心血管健康行為和因素與NAFLD的關繫.結果 具備0～1、2、3、4、5～7箇理想心血管健康行為和因素組的NAFLD患病率分彆為62.6％、48.9％、33.3％、16.1％和7.5％ (P＜0.000 1).校正年齡、性彆、經濟收入水平、文化程度等混雜因素後,理想心血管健康行為和因素與NAFLD有關,且隨著健康行為和因素箇數的增多(0～1、2、3、4、5～7),OR值(95％CI)逐漸降低,分彆為1、0.61(0.56～0.66)、0.37(0.34～0.40)、0.17(0.15 ～0.18)和0.08(0.07 ～0.09).結論 理想心血管健康行為和因素與NAFLD相關.
목적 탐토이상심혈관건강행위화인소여비주정성지방간(NAFLD)적관계.방법 이삼가2006-2007년도건강체검적101 510명개란집단공사직공위연구대상,배제음주자、심기경사、뇌졸중、악성종류이급자료불전자,최종납입54 303례,관찰연구인군중NAFLD적환병정황.근거미국심장협회정의적이상심혈관건강행위화인소,채용다인소logistic회귀모형분석이상심혈관건강행위화인소여NAFLD적관계.결과 구비0～1、2、3、4、5～7개이상심혈관건강행위화인소조적NAFLD환병솔분별위62.6％、48.9％、33.3％、16.1％화7.5％ (P＜0.000 1).교정년령、성별、경제수입수평、문화정도등혼잡인소후,이상심혈관건강행위화인소여NAFLD유관,차수착건강행위화인소개수적증다(0～1、2、3、4、5～7),OR치(95％CI)축점강저,분별위1、0.61(0.56～0.66)、0.37(0.34～0.40)、0.17(0.15 ～0.18)화0.08(0.07 ～0.09).결론 이상심혈관건강행위화인소여NAFLD상관.
Objective To investigate the relationship between ideal cardiovascular behaviors/ factors and nonalcoholic fatty liver disease.Methods In our study,54 303 workers who had participated in the 2006-2007 Kailuan health examination with complete data and without history of drinking,myocardial infarction,stroke or cancer,were recruited.All workers were under observation and their prevalence of nonalcoholic fatty liver disease recorded.According to the American Heart Association defmition of ideal cardiovascular health behaviors and factors,multiple logistic regression method was used to calculate the OR and 95％ CI for baseline behaviors and factors.Results The prevalence of nonalcoholic fatty liver disease according to 0-1,2,3,4,5-7 ideal cardiovascular health behaviors/factors were 62.6％,48.9％,33.3％,16.1％ and 7.5％,respectively.Results from the logistic model showed that after adjustment for age,gender,income,education level and other confounders,the ideal cardiovascular health behaviors/factors were associated with nonalcoholic fatty liver disease and the ORs (95％ CI) were reduced gradually with the increase of ideal cardiovascular health behaviors/factors,which were 1,0.61 (0.56-0.66),0.37 (0.34-0.40),0.17 (0.15-0.18) and 0.08 (0.07-0.09),respectively,in the 2,3,4,5-7 ideal behaviors/factors groups.Conclusion Ideal cardiovascular health behaviors and factors were associated with nonalcoholic fatty liver disease.
