中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
12期
1239-1242
,共4页
血塞通软胶囊%脑梗死%脑卒中
血塞通軟膠囊%腦梗死%腦卒中
혈새통연효낭%뇌경사%뇌졸중
Xuesaitong soft capsule%Cerebral infarction%Cerebral apoplexy
目的 观察血塞通软胶囊治疗脑梗死患者的临床效果.方法 收集2010年1-9月在河北联合大学附属医院门诊就诊的脑梗死患者112例,采用随机、双盲的方法将112例脑梗死患者随机分为试验组84例和对照组28例,分别给予血塞通软胶囊和银杏叶胶囊进行治疗,疗程均为28 d,以符合方案数据集(PPS)和全数据分析集(FAS)分析和比较两组患者治疗0、14、28 d时NIHSS脑卒中量表总分实测值历时性变化以及治疗前后的差值变化.统计分析采用SPSS13.5软件.结果 经PPS分析和FAS分析,对照组和试验组在治疗的各个时间段NIHSS脑卒中量表总分实测值组间比较,差异均无统计学意义(PPS分析,t值分别为0.500、0.218、0.012;FAS分析,t值分别为0.506、0.231、0.049,P均＞0.05).两组患者在治疗的0d和28 d时间点组内的NIHSS脑卒中量表总分实测值随治疗时间延长而明显降低,差异均有统计学意义(PPS的F值分别为13.89、31.18;FAS的F值分别为14.80、34.04,P均＜0.05).PPS分析和FAS分析结论一致.结论 血塞通软胶囊治疗脑梗死患者疗效确切,建议临床推广使用.
目的 觀察血塞通軟膠囊治療腦梗死患者的臨床效果.方法 收集2010年1-9月在河北聯閤大學附屬醫院門診就診的腦梗死患者112例,採用隨機、雙盲的方法將112例腦梗死患者隨機分為試驗組84例和對照組28例,分彆給予血塞通軟膠囊和銀杏葉膠囊進行治療,療程均為28 d,以符閤方案數據集(PPS)和全數據分析集(FAS)分析和比較兩組患者治療0、14、28 d時NIHSS腦卒中量錶總分實測值歷時性變化以及治療前後的差值變化.統計分析採用SPSS13.5軟件.結果 經PPS分析和FAS分析,對照組和試驗組在治療的各箇時間段NIHSS腦卒中量錶總分實測值組間比較,差異均無統計學意義(PPS分析,t值分彆為0.500、0.218、0.012;FAS分析,t值分彆為0.506、0.231、0.049,P均＞0.05).兩組患者在治療的0d和28 d時間點組內的NIHSS腦卒中量錶總分實測值隨治療時間延長而明顯降低,差異均有統計學意義(PPS的F值分彆為13.89、31.18;FAS的F值分彆為14.80、34.04,P均＜0.05).PPS分析和FAS分析結論一緻.結論 血塞通軟膠囊治療腦梗死患者療效確切,建議臨床推廣使用.
목적 관찰혈새통연효낭치료뇌경사환자적림상효과.방법 수집2010년1-9월재하북연합대학부속의원문진취진적뇌경사환자112례,채용수궤、쌍맹적방법장112례뇌경사환자수궤분위시험조84례화대조조28례,분별급여혈새통연효낭화은행협효낭진행치료,료정균위28 d,이부합방안수거집(PPS)화전수거분석집(FAS)분석화비교량조환자치료0、14、28 d시NIHSS뇌졸중량표총분실측치력시성변화이급치료전후적차치변화.통계분석채용SPSS13.5연건.결과 경PPS분석화FAS분석,대조조화시험조재치료적각개시간단NIHSS뇌졸중량표총분실측치조간비교,차이균무통계학의의(PPS분석,t치분별위0.500、0.218、0.012;FAS분석,t치분별위0.506、0.231、0.049,P균＞0.05).량조환자재치료적0d화28 d시간점조내적NIHSS뇌졸중량표총분실측치수치료시간연장이명현강저,차이균유통계학의의(PPS적F치분별위13.89、31.18;FAS적F치분별위14.80、34.04,P균＜0.05).PPS분석화FAS분석결론일치.결론 혈새통연효낭치료뇌경사환자료효학절,건의림상추엄사용.
Objective To investigate the clinical effect of Xuesaitong soft capsule in the treatment of cerebral apoplexy in cerebral infarction patients.Methods One hundred and twelve patients with cerebral infarction were selected as our subjects,who were in out-patient clinic of Affiliated Hospital of Hebei United Univemity from Jan.to Sep.in 2010.The patients were randomly divided into experimemal group(84 cases) and control group(28 cases) and they were received Xuesaitong soft capsule or Ginkgo leaf capsule for 28d.To meet the program data set(PPS) and a full analysis of data set(FAS),and compared NIHSS Stroke Scale score of the measured values of the diachronic changes at 0,14,28 d and the difference before and after treatment in the treatment of two groups of patients.Statistical analysis was done by SPSS13.5 software.Results PPS and FAS analysis showed that there were no statistic significance at each time of treated section in terms of the practical change value of cerebral apoplexy measuring scale between the experimental group and control group ((PPS:F between group:0.500,0.21 8,0.012 ; FAS:F between group:0.506,0.231,0.049 ; P ＞ 0.05).The practical change value of cerebral apoplexy measuring scale decreased obviously at 0 d and 28 d after treatment.The analysis of variance of repeated measured data indicated that there were obviously statistic significance(PPS:F inner group:13.89、31.18 ; FAS:F inner group:14.80,34.04 ;P ＜ 0.05).The analysis results were concordance through FAS and PPS.Conclusion The clinical effect of Xuesaitong soft capsule for cerebral infarction patients with cerebral apoplexy is safe,and it was suggested to apply in clinic.
