中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
12期
1259-1261
,共3页
张云芳%国建%化宝军%罗杰%李红艳
張雲芳%國建%化寶軍%囉傑%李紅豔
장운방%국건%화보군%라걸%리홍염
急性肾损伤%自身免疫性溶血%贫血
急性腎損傷%自身免疫性溶血%貧血
급성신손상%자신면역성용혈%빈혈
Acute kidney injury%Autoimmune hemolysis%Anemia
目的 探讨急性肾损伤合并自身免疫性溶血性贫血的临床特点.方法 分析2例急性肾损伤合并自身免疫性溶血性贫血患者的临床资料,结合文献复习此类疾病的临床特点及诊治思路.结果 2例患者均表现为严重的急性肾损伤、进行性加重的贫血,促红素、铁剂、叶酸补充等常规纠正贫血治疗无效,直接Coombs阳性,外周血网织红细胞升高,血清乳酸脱氢酶、血清胆红素正常,类固醇激素治疗有效.结论 急性肾损伤合并进行性贫血需考虑是否合并自身免疫性溶血,及时给予类固醇激素治疗临床效果显著.
目的 探討急性腎損傷閤併自身免疫性溶血性貧血的臨床特點.方法 分析2例急性腎損傷閤併自身免疫性溶血性貧血患者的臨床資料,結閤文獻複習此類疾病的臨床特點及診治思路.結果 2例患者均錶現為嚴重的急性腎損傷、進行性加重的貧血,促紅素、鐵劑、葉痠補充等常規糾正貧血治療無效,直接Coombs暘性,外週血網織紅細胞升高,血清乳痠脫氫酶、血清膽紅素正常,類固醇激素治療有效.結論 急性腎損傷閤併進行性貧血需攷慮是否閤併自身免疫性溶血,及時給予類固醇激素治療臨床效果顯著.
목적 탐토급성신손상합병자신면역성용혈성빈혈적림상특점.방법 분석2례급성신손상합병자신면역성용혈성빈혈환자적림상자료,결합문헌복습차류질병적림상특점급진치사로.결과 2례환자균표현위엄중적급성신손상、진행성가중적빈혈,촉홍소、철제、협산보충등상규규정빈혈치료무효,직접Coombs양성,외주혈망직홍세포승고,혈청유산탈경매、혈청담홍소정상,류고순격소치료유효.결론 급성신손상합병진행성빈혈수고필시부합병자신면역성용혈,급시급여류고순격소치료림상효과현저.
Objective To investigate the clinical characteristics of patients suffering from autoimmune hemolytic anemia(AIHA) associated with acute kidney injury (AKI).Methods The clinical data of 2 case patients with AIHA and AKI in the People's Hospital of Huadu District of Guangzhou was analyzed and associated literatures were reviewed.Results Two patients presented with severe anemia,raised reticulocyte count,positive Coomb's test,and acute renal failure.They were no effect therapy when treatment with agent of erythropoietin (EPO),iron or folic acid.The level of serum indirect bilirubin was at normal range.Liver function and serum LDH were normal too.However,treatment with corticosteroids was effective.Conclusion When patients suffering AKI occur worsening anemia,AIHA probably should be concerned.Treatment with corticosteroids early is effective.
