中国综合临床
中國綜閤臨床
중국종합림상
CLINICAL MEDICINE OF CHINA
2014年
12期
1284-1286
,共3页
秦杨%徐贤华%李改丽%李烨瑾%潘泉蓉%徐静%范丽娟
秦楊%徐賢華%李改麗%李燁瑾%潘泉蓉%徐靜%範麗娟
진양%서현화%리개려%리엽근%반천용%서정%범려연
输尿管结石%非甾体类抗炎药%α1肾上腺素能受体阻滞剂%盐酸哌替啶
輸尿管結石%非甾體類抗炎藥%α1腎上腺素能受體阻滯劑%鹽痠哌替啶
수뇨관결석%비치체류항염약%α1신상선소능수체조체제%염산고체정
Ureteral stones%Non-steroidal anti-inflammatory drugs%α1-adrenergic antagonist%Meperidine hydrochloride
目的 观察非甾体类抗炎药联合α1肾上腺素能受体阻滞剂在输尿管结石伴绞痛治疗中的临床效果.方法 将128例输尿管结石伴绞痛患者应用随机数字表分为两组,每组64例,均给予坦索罗辛0.4 mg口服,生理盐水1 000 ml静脉滴注;治疗组给予酮咯酸氨丁三醇注射液10 mg肌内注射,对照组给予盐酸哌替啶10 mg肌内注射;留院观察6～8h复查超声观察结石排出情况,仍未排出者行体外震波碎石术及其他治疗.结果 治疗组止痛有效率为96.9％ (62/64),对照组为100％ (64/64),两组止痛有效率差异无统计学意义(x2 =2.03,P=0.50);治疗组自行排石率为28.1％ (18/64),高于对照组的12.5％ (8/64),差异有统计学意义(x2=4.83,P=0.05).结论 非甾体类抗炎药能有效缓解输尿管结石引起的绞痛,其总有效率同哌替啶相当,联合α1受体阻滞剂促进排石的作用优于哌替啶.
目的 觀察非甾體類抗炎藥聯閤α1腎上腺素能受體阻滯劑在輸尿管結石伴絞痛治療中的臨床效果.方法 將128例輸尿管結石伴絞痛患者應用隨機數字錶分為兩組,每組64例,均給予坦索囉辛0.4 mg口服,生理鹽水1 000 ml靜脈滴註;治療組給予酮咯痠氨丁三醇註射液10 mg肌內註射,對照組給予鹽痠哌替啶10 mg肌內註射;留院觀察6～8h複查超聲觀察結石排齣情況,仍未排齣者行體外震波碎石術及其他治療.結果 治療組止痛有效率為96.9％ (62/64),對照組為100％ (64/64),兩組止痛有效率差異無統計學意義(x2 =2.03,P=0.50);治療組自行排石率為28.1％ (18/64),高于對照組的12.5％ (8/64),差異有統計學意義(x2=4.83,P=0.05).結論 非甾體類抗炎藥能有效緩解輸尿管結石引起的絞痛,其總有效率同哌替啶相噹,聯閤α1受體阻滯劑促進排石的作用優于哌替啶.
목적 관찰비치체류항염약연합α1신상선소능수체조체제재수뇨관결석반교통치료중적림상효과.방법 장128례수뇨관결석반교통환자응용수궤수자표분위량조,매조64례,균급여탄색라신0.4 mg구복,생리염수1 000 ml정맥적주;치료조급여동각산안정삼순주사액10 mg기내주사,대조조급여염산고체정10 mg기내주사;류원관찰6～8h복사초성관찰결석배출정황,잉미배출자행체외진파쇄석술급기타치료.결과 치료조지통유효솔위96.9％ (62/64),대조조위100％ (64/64),량조지통유효솔차이무통계학의의(x2 =2.03,P=0.50);치료조자행배석솔위28.1％ (18/64),고우대조조적12.5％ (8/64),차이유통계학의의(x2=4.83,P=0.05).결론 비치체류항염약능유효완해수뇨관결석인기적교통,기총유효솔동고체정상당,연합α1수체조체제촉진배석적작용우우고체정.
Objective To investigate the clinical effect of non-steroidal anti-inflammatory drugs and αl-adrenergic antagonist on treating patients with ureteral stones.Methods A total of 128 patients with ureteral colic due to ureteral stones were randomly divided into control and treatment group,and 64 cases in each group.Both two groups were treated with tamsulosin 0.4 mg oral,intravenous injection of saline 1000 mL Patients in treatment group were received intramuscular non-steroidal anti-inflammatory drugs(10 mg) and patients in control group were received pethidine hydrochloride(10 mg).Ultrasound exam were performed after 6-8 h to evaluate the stone expulsive rate.Extracorporeal shock wave lithotripsy and other treatment were underwent when the stone was still not discharge.Results The effective rate of analgesia was 96.9％ (62/64) in treatment group and 100％ (64/64) in control group(x2 =2.03,P =0.50).The stone expulsion rate in treatment group was 28.1％ (18/64),higher than that in control group(12.5％ (8/64),x2 =4.83,P =0.05).Conclusion It is effective to relive ureteral cohc with non-steroidal anti-inflammatory drugs only,and it is better than pethidine in promote stone expulsion when they both used with α1-adrenergic antagonist.
