CAJ | 학술논문

目的运用海德堡频域光学相干光断层扫描仪(OCT)测量正常人后极部视网膜厚度(PPRT),并探讨其在视网膜疾病诊断中的价值.方法临床病例系列研究.对2013年1月至2014年1月在绍兴市人民医院应用Spectralis OCT后极部非对称性分析软件测量99名正常人的PPRT,观察正常人PPRT的图形特征和分析上方象限、下方象限及平均厚度值,并依据早期糖尿病视网膜病变研究组(ETDRS)9分区,测量正常人黄斑区视网膜厚度,将各参数与年龄、性别、眼别及屈光度(RE)进行统计学分析.结果正常人不同年龄组之间上方象限、下方象限和平均PPRT经方差分析差异均无统计学意义(F =0.089、0.466、0.602,P均＞0.05).性别、眼别各参数比较差异无统计学意义(P＞0.05).黄斑中心凹处视网膜厚度与屈光度差异有统计学意义(r=-0.951,t=18.382,P＜0.01).在高度近视组,其平均PPRT为(290.07±11.17) μm,屈光度和平均PPRT差异有统计学意义(r=0.892,t =11.837 P＜0.01).结论正常人PPRT分析可能为与厚度相关的视网膜疾病客观定量监测提供一定的参考价值.
목적 운용해덕보빈역광학상간광단층소묘의(OCT)측량정상인후겁부시망막후도(PPRT),병탐토기재시망막질병진단중적개치.방법 림상병례계렬연구.대2013년1월지2014년1월재소흥시인민의원응용Spectralis OCT후겁부비대칭성분석연건측량99명정상인적PPRT,관찰정상인PPRT적도형특정화분석상방상한、하방상한급평균후도치,병의거조기당뇨병시망막병변연구조(ETDRS)9분구,측량정상인황반구시망막후도,장각삼수여년령、성별、안별급굴광도(RE)진행통계학분석.결과 정상인불동년령조지간상방상한、하방상한화평균PPRT경방차분석차이균무통계학의의(F =0.089、0.466、0.602,P균＞0.05).성별、안별각삼수비교차이무통계학의의(P＞0.05).황반중심요처시망막후도여굴광도차이유통계학의의(r=-0.951,t=18.382,P＜0.01).재고도근시조,기평균PPRT위(290.07±11.17) μm,굴광도화평균PPRT차이유통계학의의(r=0.892,t =11.837 P＜0.01).결론 정상인PPRT분석가능위여후도상관적시망막질병객관정량감측제공일정적삼고개치.
Objective To observe the posterior pole retinal thickness (PPRT) of normal subjects measured by Heidelberg optical coherence tomography (OCT),and evaluate its value in the diagnosis of retinal disease.Methods The PPRT of 99 normal cases were respectively measured by posterior pole Asymmetry Analysis software of Heidelberg Spectralis OCT.The image features of posterior pole retinal mapping in normal individuals were observed and the thicknesses in superior,inferior,average were analyzed.Macular retinal thickness measurements of normal individuals were obtained on all 9 Early Treatment Diabetic Retinopathy Study (ETDRS) report.All parameters were analyzed with age,gender,eye and refractive error (RE) by statistic software package.Results No difference of retinal thickness was observed between different age groups (F =0.089,0.466,0.602,P ＞0.05).No difference of retinal thickness was observed between gender and eye (P ＞0.05).Central foveal thickness had statistically difference with refractive error (r =-0.951,t =18.382,P ＜0.01).In highly myopic eyes,the PPRT were (290.07±11.17)μm.Refractive error had statistically difference with the average PPRT (r =0.892,t =11.837,P ＜0.01).Conclusions PPRT measurements in healthy eyes may provide some standard values to monitor the objective quantification of retinal diseases related to thickness.