中国医师进修杂志
中國醫師進脩雜誌
중국의사진수잡지
CHINESE JOURNAL OF POSTGRADUATES OF MEDICINE
2014年
35期
4-7
,共4页
陈原%姚德茂%李红伟%韩彦华
陳原%姚德茂%李紅偉%韓彥華
진원%요덕무%리홍위%한언화
胃肿瘤%预后%淋巴转移%因素分析,统计学
胃腫瘤%預後%淋巴轉移%因素分析,統計學
위종류%예후%림파전이%인소분석,통계학
Stomach neoplasms%Prognosis%Lymphatic metastasis%Factor analysis,statistical
目的 分析影响胃癌根治术后患者预后的临床病理因素,提高对胃癌的认识及治疗水平,为临床诊治提供依据.方法 回顾性分析1999年1月至2009年12月收治并行标准胃癌根治术的胃癌患者的临床病理资料,符合标准的581例患者共随访到179例,建立数据库用SPSS 13.0软件进行分析.结果 单因素分析表明:胃癌根治术后患者预后影响因素包括年龄、肿瘤部位、肿瘤最大直径、大体类型、组织学类型、浸润深度、TNM分期、手术方式、标本切缘和淋巴结转移个数(P＜0.05或＜0.01);性别与预后无相关性(P＞0.05).多因素Cox回归分析提示:TNM分期和淋巴结转移个数是影响胃癌患者预后的独立因素,其中淋巴结转移个数是影响胃癌预后最重要的因素.结论 TNM分期和淋巴结转移个数是胃癌预后的独立影响因素,其中淋巴结转移个数是胃癌预后最为重要的影响因素,因此国际抗癌联盟的淋巴结分期是胃癌预后更好的判断指标.
目的 分析影響胃癌根治術後患者預後的臨床病理因素,提高對胃癌的認識及治療水平,為臨床診治提供依據.方法 迴顧性分析1999年1月至2009年12月收治併行標準胃癌根治術的胃癌患者的臨床病理資料,符閤標準的581例患者共隨訪到179例,建立數據庫用SPSS 13.0軟件進行分析.結果 單因素分析錶明:胃癌根治術後患者預後影響因素包括年齡、腫瘤部位、腫瘤最大直徑、大體類型、組織學類型、浸潤深度、TNM分期、手術方式、標本切緣和淋巴結轉移箇數(P＜0.05或＜0.01);性彆與預後無相關性(P＞0.05).多因素Cox迴歸分析提示:TNM分期和淋巴結轉移箇數是影響胃癌患者預後的獨立因素,其中淋巴結轉移箇數是影響胃癌預後最重要的因素.結論 TNM分期和淋巴結轉移箇數是胃癌預後的獨立影響因素,其中淋巴結轉移箇數是胃癌預後最為重要的影響因素,因此國際抗癌聯盟的淋巴結分期是胃癌預後更好的判斷指標.
목적 분석영향위암근치술후환자예후적림상병리인소,제고대위암적인식급치료수평,위림상진치제공의거.방법 회고성분석1999년1월지2009년12월수치병행표준위암근치술적위암환자적림상병리자료,부합표준적581례환자공수방도179례,건립수거고용SPSS 13.0연건진행분석.결과 단인소분석표명:위암근치술후환자예후영향인소포괄년령、종류부위、종류최대직경、대체류형、조직학류형、침윤심도、TNM분기、수술방식、표본절연화림파결전이개수(P＜0.05혹＜0.01);성별여예후무상관성(P＞0.05).다인소Cox회귀분석제시:TNM분기화림파결전이개수시영향위암환자예후적독립인소,기중림파결전이개수시영향위암예후최중요적인소.결론 TNM분기화림파결전이개수시위암예후적독립영향인소,기중림파결전이개수시위암예후최위중요적영향인소,인차국제항암련맹적림파결분기시위암예후경호적판단지표.
Objective To analyze the clinical and pathological factors that affect the prognosis of gastric cancer patients after radical resection,and study the relationship between biological behavior of gastric cancer and clinical so as to provide clues to the basis for clinical diagnosis and treatment.Methods The clinical and pathological data of the gastric cancer patients who underwent radical resection from January 1999 to December 2009 were retrospectively analyzed.Of the 581 eligible patients were followed up in 179 cases.A database was established for SPSS 13.0 software analysis.Results Single factor analysis showed that the prognosis influencing factors in gastric cancer patients after radical resection were age,tumor location,tumor size,gross type,histological type,depth of invasion,TNM stage,surgical procedure,the cancerous remains of specimen surgical margin and the number of lymph node metastasis (P ＜ 0.05 or ＜ 0.01),no correlation was found between gender and prognosis (P ＞ 0.05).Multiple Cox regression analysis showed that TNM stage and number of lymph node metastasis were independent gastric cancer prognostic influencing factors,and the number of lymph node metastasis was found to be the more significant factor.Conclusions TNM stage and the number of lymph node metastasis are independent prognostic influencing factors in gastric cancer,and the number of lymph node metastasis is the more important factor in gastric cancer prognosis.Therefore,Union for International Cancer Control lymph node staging of gastric cancer is a better indicator for gastric cancer prognosis.
