CAJ | 학술논문

婴儿痉挛症是一种独特的,且具有年龄特异性的婴儿早期癫痫综合征.具有发病年龄早、发作形式特殊、进行性智力减退、脑电图呈高峰节律紊乱等特征.其病因复杂、多样,发病机制迄今尚未明确.虽然目前国内外对于其治疗相关的指南、共识小断推陈出新,但该病治疗方面仍存在困难,遗留智能缺陷等后遗症.现通过对近年来的文献复习,介绍婴儿痉挛症最近的治疗进展情况.重点介绍皮质激素和氨己烯酸的使用,以及婴儿痉挛征的质量控制指标.
영인경련증시일충독특적,차구유년령특이성적영인조기전간종합정.구유발병년령조、발작형식특수、진행성지력감퇴、뇌전도정고봉절률문란등특정.기병인복잡、다양,발병궤제흘금상미명학.수연목전국내외대우기치료상관적지남、공식소단추진출신,단해병치료방면잉존재곤난,유류지능결함등후유증.현통과대근년래적문헌복습,개소영인경련증최근적치료진전정황.중점개소피질격소화안기희산적사용,이급영인경련정적질량공제지표.
Infantile spasms constitutes an unique,age-specific epilepsy syndrome of early infancy characterized by epileptic spasms often accompanied by neurodevelopmental regression and an electroencephalograph finding of hypsarrhythmia.For the complex and various etiologies,the pathogenesis remains unclear.Although the relevant guidelines and consensuses are being updated all the time,but proven therapies are still limited because of efficacy,tolerability,at times even availability.In this paper,the current findings regarding up-to-date advances in the treatment of infant spasms were reviewed,especially in use of the corticosteroid and vigabatrin as well as the quality-of-care indicators for infantile spasms.