CAJ | 학술논문

循环肿瘤细胞(CTC)具有的特异性(上皮间质转化、与骨髓来源细胞的融合、抗失巢凋亡)决定了将其作为原代目标进行培养的必要性,所培养出的细胞株将为进一步研究恶性肿瘤的转移机制提供良好的物质基础,为患者的靶向治疗提供个体化的新方向.
순배종류세포(CTC)구유적특이성(상피간질전화、여골수래원세포적융합、항실소조망)결정료장기작위원대목표진행배양적필요성,소배양출적세포주장위진일보연구악성종류적전이궤제제공량호적물질기출,위환자적파향치료제공개체화적신방향.
The specificity of circulating tumor cell (CTC) such as epithelial-mesenchymal transition,fusion of bone marrow-derived cells,resistance anoikis determines the necessity of cell cultivating.The produced cell lines can provide good material basis for further research of malignant tumor metastasis,also provide individualized targeted therapy for patients with a new direction.