CAJ | 학술논문

角膜基质层是构成角膜的主要结构,近年来对角膜基质层结构的研究主要采用X线衍射、电子显微镜及非线性光学技术.研究者利用这些技术,从轴方向和子午线方向上探究角膜基质层胶原纤维的分布规律,从而探讨这些分布规律与角膜基质层力学特性关系.研究表明,临床上常见的角膜扩张症(如圆锥角膜、准分子激光原位角膜磨镶术术后角膜扩张症)也被证实与病变角膜的结构改变导致力学特性改变有关.利用这一结果,研究者积极探讨治疗这类角膜扩张症的方法.
각막기질층시구성각막적주요결구,근년래대각막기질층결구적연구주요채용X선연사、전자현미경급비선성광학기술.연구자이용저사기술,종축방향화자오선방향상탐구각막기질층효원섬유적분포규률,종이탐토저사분포규률여각막기질층역학특성관계.연구표명,림상상상견적각막확장증(여원추각막、준분자격광원위각막마양술술후각막확장증)야피증실여병변각막적결구개변도치역학특성개변유관.이용저일결과,연구자적겁탐토치료저류각막확장증적방법.
Corneal stroma is the primary structure of cornea.The common technologies in studying the structure of corneal stroma are X-Ray scattering,electron microscopy and nonlinear optical imaging (NLO).By these techniques,researchers try to find the distribution rule of collagen fibers along axial and meridian direction and to find the relation between the mechanical property and the rules.It is proved that corneal ectasia,such as keratoconus and post-LASIK ectasia,is induced by the change of coneal mechanical property,which is caused by the change of corneal structure.Researchers are trying to find methods to treat these corneal ectasia.