国际眼科纵览
國際眼科縱覽
국제안과종람
OREIGN MEDICAL SCIENCES
2014年
6期
400-402
,共3页
贝伐单抗%血管内皮生长因子%糖尿病%增生性糖尿病视网膜病变
貝伐單抗%血管內皮生長因子%糖尿病%增生性糖尿病視網膜病變
패벌단항%혈관내피생장인자%당뇨병%증생성당뇨병시망막병변
bevacizumab%vascular endothelial growth factor%diabetes mellitus%proliferative diabetic retinopathy
糖尿病视网膜病变(diabetic retinopathy,DR)是糖尿病的严重并发症,尤其是增生性糖尿病视网膜病变(proliferative diabetic retinopathy,PDR)是工作年龄人群中首位致盲性眼病.近年来采用血管内皮生长因子抑制剂贝伐单抗(Bevacizumab,商品名Avastin)治疗PDR取得一定成效,其可促进玻璃体积血吸收,视网膜新生血管消退,减轻黄斑水肿,降低视网膜脱离的发生率,甚至使PDR患者避免玻璃体手术.
糖尿病視網膜病變(diabetic retinopathy,DR)是糖尿病的嚴重併髮癥,尤其是增生性糖尿病視網膜病變(proliferative diabetic retinopathy,PDR)是工作年齡人群中首位緻盲性眼病.近年來採用血管內皮生長因子抑製劑貝伐單抗(Bevacizumab,商品名Avastin)治療PDR取得一定成效,其可促進玻璃體積血吸收,視網膜新生血管消退,減輕黃斑水腫,降低視網膜脫離的髮生率,甚至使PDR患者避免玻璃體手術.
당뇨병시망막병변(diabetic retinopathy,DR)시당뇨병적엄중병발증,우기시증생성당뇨병시망막병변(proliferative diabetic retinopathy,PDR)시공작년령인군중수위치맹성안병.근년래채용혈관내피생장인자억제제패벌단항(Bevacizumab,상품명Avastin)치료PDR취득일정성효,기가촉진파리체적혈흡수,시망막신생혈관소퇴,감경황반수종,강저시망막탈리적발생솔,심지사PDR환자피면파리체수술.
Diabetic retinopathy is a serious complication of diabetes mellitus,especially proliferative diabetic retinopathy(PDR),which is a leading cause of visual impairment and blindness among working-age people.In recent years,the efficacy of vascular endothelial growth factor inhibitor (Bevacizumab) has been recognized for the treatment of PDR.Intravitreal bevacizumab can accelerate absorption of vitreous hemorrhage and inhibit neovascularization,alleviate macular edema and vascular leakage and decrease the incidence of retinal detachment.
