CAJ | 학술논문

眼眶炎性假瘤(orbital inflammatory pseudotumor,OIP)是一种常见的良性非特异性炎性眼眶疾病,好发于青壮年.发病部位可能涉及一个或多个眶内结构,也可能发生于眼眶外.其病因和发病机制至今未明,主要有感染与免疫等学说.根据其侵犯的部位和病变的不同程度,临床表现也各异,包括复视、眼睑下垂、视力下降、眼球红肿、疼痛、眼球突出、眼外肌运动受限等.计算机断层扫描和磁共振成像可协助诊断和鉴别诊断.该病的药物治疗最为常见,主要包括糖皮质激素和免疫抑制剂;对糖皮质激素治疗效果欠佳或对糖皮质激素存在禁忌证者可采用放射治疗;对药物治疗效果欠佳的纤维硬化型和局限肿块型可手术治疗.
안광염성가류(orbital inflammatory pseudotumor,OIP)시일충상견적량성비특이성염성안광질병,호발우청장년.발병부위가능섭급일개혹다개광내결구,야가능발생우안광외.기병인화발병궤제지금미명,주요유감염여면역등학설.근거기침범적부위화병변적불동정도,림상표현야각이,포괄복시、안검하수、시력하강、안구홍종、동통、안구돌출、안외기운동수한등.계산궤단층소묘화자공진성상가협조진단화감별진단.해병적약물치료최위상견,주요포괄당피질격소화면역억제제;대당피질격소치료효과흠가혹대당피질격소존재금기증자가채용방사치료;대약물치료효과흠가적섬유경화형화국한종괴형가수술치료.
Orbital inflammatory pseudotumor (OIP) refers to benign nonspecific inflammatory conditions of the orbit,which usually occurs in young adults.Single or multiple intra-orbital structures may be involved.Extra-orbital extension can also occur.Although the causes of OIP are unknown,it is thought to be associated with autoimmune condition or infection.The clinical manifestation varies according to the anatomic involvement and the degree of inflammation progress.Common clinical manifestations include ptosis,diplopia,poor vision,eyeball swelling,pain,proptosis,etc.Both computed tomography (CT) and magnetic resonance imaging (MRI) are frequently used to investigate OIP.OIP is an exclusion diagnosis based on a combination of clinical and radiographic findings.The mainstay initial therapy for OIP is oral corticosteroids and immunomodulatory agents.Low-dose radiotherapy has been successful in many cases of recurrent myositis.Limited inflammatory pseudotumor can be treated surgically.