CAJ | 학술논문

研究表明,2型糖尿病患者肠道菌群结构及功能与健康人不同,肠道菌群可能通过干预宿主营养及能量的吸收利用,促进脂肪的合成及存储,引发慢性低度炎性反应等机制影响2型糖尿病的发展.多项针对肠道菌群的治疗措施在2型糖尿病的动物模型和人群研究中开展,表明饮食、运动及药物均可通过干预肠道菌群的结构及功能影响糖尿病的发生和发展.干预肠道菌群可能成为今后糖尿病防治领域的重要手段之一.
연구표명,2형당뇨병환자장도균군결구급공능여건강인불동,장도균군가능통과간예숙주영양급능량적흡수이용,촉진지방적합성급존저,인발만성저도염성반응등궤제영향2형당뇨병적발전.다항침대장도균군적치료조시재2형당뇨병적동물모형화인군연구중개전,표명음식、운동급약물균가통과간예장도균군적결구급공능영향당뇨병적발생화발전.간예장도균군가능성위금후당뇨병방치영역적중요수단지일.
Recent studies show that the structure and function of gut microbiota in patients with type 2 diabetes differ from those in healthy people.Gut microbiota may play roles in the development of type 2 diabetes by interfering the absorption and utilization of nutrients and energy,promoting the synthesis and storage of fat and inducing chronic low-grade inflammation.Animal studies as well as human studies showed that diet,exercise and drugs could affect the occurrence and development of diabetes through intervening the structure and function of gut microbiota.Intervention of gut microbiota may become one of the important strategies for prevention and treatment of diabetes in the future.