CAJ | 학술논문

糖尿病患者对幽门螺杆菌(Hp)的易感性高于正常人群,且Hp感染可作为糖尿病血管病变的危险因素,但目前对此尚没有统一的结论.Hp感染通过增加急、慢性期反应物和炎性介质、破坏血管内皮细胞、改变血脂水平、氧化状态及凝血状况等机制,参与糖尿病各种血管病变的发生与发展.
당뇨병환자대유문라간균(Hp)적역감성고우정상인군,차Hp감염가작위당뇨병혈관병변적위험인소,단목전대차상몰유통일적결론.Hp감염통과증가급、만성기반응물화염성개질、파배혈관내피세포、개변혈지수평、양화상태급응혈상황등궤제,삼여당뇨병각충혈관병변적발생여발전.
The susceptibility to Helicobacter pylori (Hp) is significantly higher in patients with diabetes than that in healthy controls.There is still controversial about whether Hp infection is the risk factor of diabetic vasculopathy.Hp infection may involve in the occurrence and development of diabetic vasculopathy by accelerating acute and chronic inflammation reaction,increasing inflammatory factors,injurying vascular endothelial cells,changing plasma lipid profile,altering the state of oxidation and influencing the coagulative function,etc.