CAJ | 학술논문

目前关于体内棕色脂肪的检测主要分为半定量检测和功能检测两大类.半定量检测方法主要包括正电子发射断层扫描(PET)/CT、MRI等影像学检查,功能检测方法主要包括间接热量测定法、交感神经张力测定法、测温法等.此外,还可以通过称重法、检测棕色脂肪经典标志物表达来评估.对棕色脂肪组织的检测有助于进一步探讨肥胖的发生机制,从而为其治疗提供新的靶点.
목전관우체내종색지방적검측주요분위반정량검측화공능검측량대류.반정량검측방법주요포괄정전자발사단층소묘(PET)/CT、MRI등영상학검사,공능검측방법주요포괄간접열량측정법、교감신경장력측정법、측온법등.차외,환가이통과칭중법、검측종색지방경전표지물표체래평고.대종색지방조직적검측유조우진일보탐토비반적발생궤제,종이위기치료제공신적파점.
Recently,the methods to analyze brown adipose tissue in vivo mainly include the semiquantitative assessments and the functional assessments.The semi-quantitative assessments mainly focus on imaging evaluations,such as positron emission tomography(PET)/CT,and MRI.The functional assessments of brown adipose tissue include indirect calorimetry,measurement of sympathetic tone and measurement of core body temperature.Except for these methods,weighing the brown adipose tissue and testing the expression of typical markers also work.The assessment of brown adipose tissue is helpful in clarifying the pathogenesis of obesity,as well as in finding a new target for treatmet of obesity.