国际流行病学传染病学杂志
國際流行病學傳染病學雜誌
국제류행병학전염병학잡지
INTERNATIONAL JOURNAL OF EPIDEMIOLOGY AND INFECTIOUS DISEASE
2014年
6期
407-411
,共5页
戴菲菲%朱佳清%赖美红%吕苏珍
戴菲菲%硃佳清%賴美紅%呂囌珍
대비비%주가청%뢰미홍%려소진
重症监护病房%院内感染%目标性监测%Meta分析
重癥鑑護病房%院內感染%目標性鑑測%Meta分析
중증감호병방%원내감염%목표성감측%Meta분석
Intensive care units%Heath care-associated infections%Targeted surveillance%Meta-analysis
目的 分析目标性监测综合干预在我国ICU医院感染防控中的效果.方法 文献检索中国知网、维普和万方数据库,将基于ICU医院感染目标性监测综合干预的前后对照研究纳入,并应用R 3.0.3软件进行Meta分析.结果 共纳入11篇文献.综合干预前后,各项感染率的合并相对危险度(RR)分别为:感染率0.70(95 ％CI:0.56～0.87),例次感染率0.70(95％ CI:0.58～0.84),千日感染率0.76(95％CI:0.60～0.95),千日例次感染率0.66(95％CI:0.54～0.80),干预前后差异均有统计学意义(P均＜0.05).干预前后各项器械使用率合并RR分别为:中心静脉插管0.96 (95％CI:0.82～1.12),呼吸机1.06(95％CI:0.97～1.15),导尿管0.93(95％CI:0.86～1.00),差异均无统计学意义(P均＞0.05);中心静脉插管、呼吸机相关感染率干预后合并RR分别为:0.75 (95％CI:0.53～0.88)、0.63(95％CI:0.56～0.72),差异均有统计学意义(P均＜0.05),但导尿管相关感染干预后仅有下降趋势0.85 (95％CI:0.68～1.06),差异并无统计学意义(P均＞0.05).结论 基于目标性监测的综合干预措施对医院感染防控效果显著,并且具有进一步挖掘空间,值得进一步临床推广应用.
目的 分析目標性鑑測綜閤榦預在我國ICU醫院感染防控中的效果.方法 文獻檢索中國知網、維普和萬方數據庫,將基于ICU醫院感染目標性鑑測綜閤榦預的前後對照研究納入,併應用R 3.0.3軟件進行Meta分析.結果 共納入11篇文獻.綜閤榦預前後,各項感染率的閤併相對危險度(RR)分彆為:感染率0.70(95 ％CI:0.56～0.87),例次感染率0.70(95％ CI:0.58～0.84),韆日感染率0.76(95％CI:0.60～0.95),韆日例次感染率0.66(95％CI:0.54～0.80),榦預前後差異均有統計學意義(P均＜0.05).榦預前後各項器械使用率閤併RR分彆為:中心靜脈插管0.96 (95％CI:0.82～1.12),呼吸機1.06(95％CI:0.97～1.15),導尿管0.93(95％CI:0.86～1.00),差異均無統計學意義(P均＞0.05);中心靜脈插管、呼吸機相關感染率榦預後閤併RR分彆為:0.75 (95％CI:0.53～0.88)、0.63(95％CI:0.56～0.72),差異均有統計學意義(P均＜0.05),但導尿管相關感染榦預後僅有下降趨勢0.85 (95％CI:0.68～1.06),差異併無統計學意義(P均＞0.05).結論 基于目標性鑑測的綜閤榦預措施對醫院感染防控效果顯著,併且具有進一步挖掘空間,值得進一步臨床推廣應用.
목적 분석목표성감측종합간예재아국ICU의원감염방공중적효과.방법 문헌검색중국지망、유보화만방수거고,장기우ICU의원감염목표성감측종합간예적전후대조연구납입,병응용R 3.0.3연건진행Meta분석.결과 공납입11편문헌.종합간예전후,각항감염솔적합병상대위험도(RR)분별위:감염솔0.70(95 ％CI:0.56～0.87),례차감염솔0.70(95％ CI:0.58～0.84),천일감염솔0.76(95％CI:0.60～0.95),천일례차감염솔0.66(95％CI:0.54～0.80),간예전후차이균유통계학의의(P균＜0.05).간예전후각항기계사용솔합병RR분별위:중심정맥삽관0.96 (95％CI:0.82～1.12),호흡궤1.06(95％CI:0.97～1.15),도뇨관0.93(95％CI:0.86～1.00),차이균무통계학의의(P균＞0.05);중심정맥삽관、호흡궤상관감염솔간예후합병RR분별위:0.75 (95％CI:0.53～0.88)、0.63(95％CI:0.56～0.72),차이균유통계학의의(P균＜0.05),단도뇨관상관감염간예후부유하강추세0.85 (95％CI:0.68～1.06),차이병무통계학의의(P균＞0.05).결론 기우목표성감측적종합간예조시대의원감염방공효과현저,병차구유진일보알굴공간,치득진일보림상추엄응용.
Objective To evaluate the results of infection-control practice based on targeted surveillance of health care-associated infections(HAIs) in the ICUs in our country.Methods CNKI,VIP and WanFang Data were searched for comparative studies on infection-control practice based on targeted surveillance of health care-associated infections (HAIs) in the ICUs.Meta-analyses were performed by using R3.0.3 software.Results Eleven studies met eligibility criteria.Pooled meta-analyses of eligible studies revealed that relative risks (RRs) for adjusted infection rate,case infection rate,daily infection rate,and case daily infection rate were 0.70(95％CI:0,56-0.87),0.70 (95％CI:0.58-0.84),0.76 (95％CI:0.60-0.95) and 0.66 (95％CI:0.54-0.80),respectively,with significant differences between before and after infection-control practice (P all ＜0.05).The RRs were 0.96 (95％CI:0.82-1.12) for central venous catheter use,1.06 (95％CI:0.97-1.15) for ventilatoruse,and 0.93(95％CI:0.86-1.00)for urinary tract use,all without any significant differences (P all ＞0.05).The RRs for ventilator associated pneumonia and catheter-related bloodstream infections were 0.68 (95％CI:0.53-0.88) and 0.63 (95％CI:0.56-0.72),respectively,with significant reduction in infection after infection-control practice (P all ＜0.05),while no significant reduction in catheter-associated urinary tract infection was found [RR:0.85 (95％CI:0.68-1.06)].Conclusions Infection-control practice based on targeted surveillance may have a positive impact on the risk of HAIs,which worth further study and implementation in the ICUs.
