中华医学杂志
中華醫學雜誌
중화의학잡지
National Medical Journal of China
2015年
2期
138-141
,共4页
俞剑伟%安贺娟%苏惠%李恕军%杨浪%谢惠%金鹏%李爱琴%盛剑秋
俞劍偉%安賀娟%囌惠%李恕軍%楊浪%謝惠%金鵬%李愛琴%盛劍鞦
유검위%안하연%소혜%리서군%양랑%사혜%금붕%리애금%성검추
螺杆菌,幽门%危险因素%横断面研究
螺桿菌,幽門%危險因素%橫斷麵研究
라간균,유문%위험인소%횡단면연구
Helicobacter pylori%Risk factors%Cross-sectional studies
目的 研究边防陆军及海军幽门螺杆菌(Hp)感染现状并分析其影响因素,为降低Hp感染率提供相应的理论依据.方法 自2013年9至1 1月横断面抽取内蒙和舟山地区18个陆海军男性新兵人群共1 732名(年龄17 ～ 24岁),现场进行13C尿素呼气试验,并指导其填写全国幽门螺杆菌感染调查问卷,内容包含62个Hp感染相关因素.自2013年4至10月抽取舟山地区5个海军男性老兵人群共513名(年龄19～51岁),现场进行13C尿素呼气试验.采用x2检验及多元Logistic回归分析Hp感染影响因素.结果 最终共纳入新、老士兵2 162名.1 649名新兵完成了2个调查,陆军新兵Hp感染率为47.0％ (377/802),海军新兵Hp感染率为46.0％(390/847),新兵总感染率为46.5％ (768/1 649),低于10年前的感染率52.9％;家庭成员数多、清洁餐具少用洗洁精、初次饮酒年龄小、进食果蔬前未削皮与新兵Hp感染相关(均P＜0.05);年龄、文化程度、餐前洗手等与新兵Hp感染无明显相关(均P＞0.05);兵源地为华南地区及华西地区的Hp感染率较高.与513名老兵13C尿素呼气试验结果比较显示,入伍时间与Hp感染率有关,入伍＜1个月的新兵Hp感染率为46.6％(768/1 649),1～2年老兵Hp感染率为59.2％ (180/304),＞2年老兵Hp感染率为63.2％(132/209) (P ＜0.05),老兵总感染率为60.8％ (312/513).多因素Logistic回归分析结果显示:家庭成员数与Hp感染呈正相关(OR=1.574,95％ CI:1.077～2.301),使用洗洁精、初次饮酒年龄、进食果蔬前削皮与Hp感染呈负相关(OR=0.538、0.638、0.855;95％ CI:0.362～0.798、0.486 ～0.837、0.457～0.961).结论 陆海军男性新兵Hp感染率相似,但Hp总感染率较10年前明显降低,流行地区也有了相应变化;Hp感染存在家庭聚集性;家庭成员数多、未成年人饮酒、少用洗洁精清洁餐具和进食果蔬未削皮是新兵Hp感染的重要危害因素;入伍时间与Hp感染存在相关性.
目的 研究邊防陸軍及海軍幽門螺桿菌(Hp)感染現狀併分析其影響因素,為降低Hp感染率提供相應的理論依據.方法 自2013年9至1 1月橫斷麵抽取內矇和舟山地區18箇陸海軍男性新兵人群共1 732名(年齡17 ～ 24歲),現場進行13C尿素呼氣試驗,併指導其填寫全國幽門螺桿菌感染調查問捲,內容包含62箇Hp感染相關因素.自2013年4至10月抽取舟山地區5箇海軍男性老兵人群共513名(年齡19～51歲),現場進行13C尿素呼氣試驗.採用x2檢驗及多元Logistic迴歸分析Hp感染影響因素.結果 最終共納入新、老士兵2 162名.1 649名新兵完成瞭2箇調查,陸軍新兵Hp感染率為47.0％ (377/802),海軍新兵Hp感染率為46.0％(390/847),新兵總感染率為46.5％ (768/1 649),低于10年前的感染率52.9％;傢庭成員數多、清潔餐具少用洗潔精、初次飲酒年齡小、進食果蔬前未削皮與新兵Hp感染相關(均P＜0.05);年齡、文化程度、餐前洗手等與新兵Hp感染無明顯相關(均P＞0.05);兵源地為華南地區及華西地區的Hp感染率較高.與513名老兵13C尿素呼氣試驗結果比較顯示,入伍時間與Hp感染率有關,入伍＜1箇月的新兵Hp感染率為46.6％(768/1 649),1～2年老兵Hp感染率為59.2％ (180/304),＞2年老兵Hp感染率為63.2％(132/209) (P ＜0.05),老兵總感染率為60.8％ (312/513).多因素Logistic迴歸分析結果顯示:傢庭成員數與Hp感染呈正相關(OR=1.574,95％ CI:1.077～2.301),使用洗潔精、初次飲酒年齡、進食果蔬前削皮與Hp感染呈負相關(OR=0.538、0.638、0.855;95％ CI:0.362～0.798、0.486 ～0.837、0.457～0.961).結論 陸海軍男性新兵Hp感染率相似,但Hp總感染率較10年前明顯降低,流行地區也有瞭相應變化;Hp感染存在傢庭聚集性;傢庭成員數多、未成年人飲酒、少用洗潔精清潔餐具和進食果蔬未削皮是新兵Hp感染的重要危害因素;入伍時間與Hp感染存在相關性.
목적 연구변방륙군급해군유문라간균(Hp)감염현상병분석기영향인소,위강저Hp감염솔제공상응적이론의거.방법 자2013년9지1 1월횡단면추취내몽화주산지구18개륙해군남성신병인군공1 732명(년령17 ～ 24세),현장진행13C뇨소호기시험,병지도기전사전국유문라간균감염조사문권,내용포함62개Hp감염상관인소.자2013년4지10월추취주산지구5개해군남성노병인군공513명(년령19～51세),현장진행13C뇨소호기시험.채용x2검험급다원Logistic회귀분석Hp감염영향인소.결과 최종공납입신、로사병2 162명.1 649명신병완성료2개조사,륙군신병Hp감염솔위47.0％ (377/802),해군신병Hp감염솔위46.0％(390/847),신병총감염솔위46.5％ (768/1 649),저우10년전적감염솔52.9％;가정성원수다、청길찬구소용세길정、초차음주년령소、진식과소전미삭피여신병Hp감염상관(균P＜0.05);년령、문화정도、찬전세수등여신병Hp감염무명현상관(균P＞0.05);병원지위화남지구급화서지구적Hp감염솔교고.여513명노병13C뇨소호기시험결과비교현시,입오시간여Hp감염솔유관,입오＜1개월적신병Hp감염솔위46.6％(768/1 649),1～2년노병Hp감염솔위59.2％ (180/304),＞2년노병Hp감염솔위63.2％(132/209) (P ＜0.05),노병총감염솔위60.8％ (312/513).다인소Logistic회귀분석결과현시:가정성원수여Hp감염정정상관(OR=1.574,95％ CI:1.077～2.301),사용세길정、초차음주년령、진식과소전삭피여Hp감염정부상관(OR=0.538、0.638、0.855;95％ CI:0.362～0.798、0.486 ～0.837、0.457～0.961).결론 륙해군남성신병Hp감염솔상사,단Hp총감염솔교10년전명현강저,류행지구야유료상응변화;Hp감염존재가정취집성;가정성원수다、미성년인음주、소용세길정청길찬구화진식과소미삭피시신병Hp감염적중요위해인소;입오시간여Hp감염존재상관성.
Objective To explore the Helicobacter pylori(Hp) infection rate among army and navy recruits,examine its associated risk factors and provide theoretic rationales for Hp control.Methods A cross-sectionalstudy was performed for 1 732 subjects (aged 17-24 years) selected from 18 new recruit populations in Inner Mongolia and Zhoushan area from September 2013 to November 2013.Hp infection was detected by 13 C-urea breath test.Meanwhile,a questionnaire containing 62 potential factors related to Hp infection was surveyed.In addition,13 C-urea breath test was performed in 513 navy veterans (aged 19-51 years) in Zhoushan area from April 2013 to October 2013.The data of risk factors were analyzed by x2 test and multivariate Logistic regression.Results A total of 2 162 soldiers were enrolled and 1 649 new recruits completed two surveys.The overall Hp infection rate was 46.5％ (768/1 649),which is lower than the previous studies(52.9％).And it was 47.0％ (377/802) in army new recruits and 46.0％ (390/847) in navy new recruits.For new recruits,Hp infection was associated with number of family members,washing tableware with detergents,first drinking age and paring fruits before eating (all P ＜ 0.05).However,there was no association with age,education level or washing hands before meal (all P ＞ 0.05).The Hp infection rate was higher in recruits from the West China and North China.In addition,the infection rate was 60.8％ (312/513) in a population of 513 veterans.It was 46.6％ (768/1 649) in recruits less than onemonth of service,59.2％ (180/304) in recruits less than two years of service and 63.2％ (132/209) in recruits more than two years of service,the difference had statistical significance (P ＜ 0.05).Logistic analysis of multiple variables showed that number of family members,washing tableware with detergents,first drinking age and paring fruits before eating were independent risk factors (OR =1.574,0.538,0.638,0.855 ; 95％ CI:1.077-2.301,0.362-0.798,0.486-0.837,0.457-0.961).Conclusions The Hp infection rate is similar between army and navy recruits.It has dropped significantly and its epidemic region changed in new male recruits compared to a decade ago in china.Hp infection clustered within families.The factors including fewer family members,washing tableware without detergents,first drinking at young age and no paring fruits before eating are risk factors of Hpinfection.And a longer service time is associated with higher Hp infection rate in recruits.
