中华心律失常学杂志
中華心律失常學雜誌
중화심률실상학잡지
CHINESE JOURNAL OF CARDIAC ARRHYTHMIAS
2014年
6期
451-453
,共3页
陈信光%张凤祥%陈明龙%杨兵%陈红武%居维竹%曹克将
陳信光%張鳳祥%陳明龍%楊兵%陳紅武%居維竹%曹剋將
진신광%장봉상%진명룡%양병%진홍무%거유죽%조극장
Brugada综合征%体温%校正的QT间期
Brugada綜閤徵%體溫%校正的QT間期
Brugada종합정%체온%교정적QT간기
Brugada syndrome%Body temperature%QT interval corrected for heart rate
目的 探讨Brugada综合征(BrS)患者不同体温状态对心电图校正的QT间期(QTc)的影响,并对两者进行相关性分析,阐述其可能的机制及临床意义.方法 选择2008年5月至2013年5月在南京医科大学第一附属医院明确诊断的BrS患者为实验组,以年龄、性别相匹配的阵发性室上性心动过速(PSVT)患者为对照组,对每例患者均每日多次测量体温并同时行心电图检查,采用Bazett公式计算QTc,将体温和QTc关系绘制成散点图并进行相关性检验.结果 8例BrS患者均为男性,平均年龄(47.38±15.05)岁,均有晕厥史,有家族猝死史(1例),临床记录室性心动过速(VT)或心室颤动(VF)4例,电生理检查(EPS)诱发VT或VF 5例.8例PSVT患者(男女比例为4∶4),平均年龄(43.75±10.47)岁,房室结折返性心动过速5例,房室折返性心动过速3例.BrS组体温与QTc之间具有相关性,相关系数0.6(P<0.05),而对照组两者之间无相关性(P>0.05).结论 BrS患者体温与QTc呈正相关,随着体温的升高,QTc呈升高趋势,容易发生室性心律失常.
目的 探討Brugada綜閤徵(BrS)患者不同體溫狀態對心電圖校正的QT間期(QTc)的影響,併對兩者進行相關性分析,闡述其可能的機製及臨床意義.方法 選擇2008年5月至2013年5月在南京醫科大學第一附屬醫院明確診斷的BrS患者為實驗組,以年齡、性彆相匹配的陣髮性室上性心動過速(PSVT)患者為對照組,對每例患者均每日多次測量體溫併同時行心電圖檢查,採用Bazett公式計算QTc,將體溫和QTc關繫繪製成散點圖併進行相關性檢驗.結果 8例BrS患者均為男性,平均年齡(47.38±15.05)歲,均有暈厥史,有傢族猝死史(1例),臨床記錄室性心動過速(VT)或心室顫動(VF)4例,電生理檢查(EPS)誘髮VT或VF 5例.8例PSVT患者(男女比例為4∶4),平均年齡(43.75±10.47)歲,房室結摺返性心動過速5例,房室摺返性心動過速3例.BrS組體溫與QTc之間具有相關性,相關繫數0.6(P<0.05),而對照組兩者之間無相關性(P>0.05).結論 BrS患者體溫與QTc呈正相關,隨著體溫的升高,QTc呈升高趨勢,容易髮生室性心律失常.
목적 탐토Brugada종합정(BrS)환자불동체온상태대심전도교정적QT간기(QTc)적영향,병대량자진행상관성분석,천술기가능적궤제급림상의의.방법 선택2008년5월지2013년5월재남경의과대학제일부속의원명학진단적BrS환자위실험조,이년령、성별상필배적진발성실상성심동과속(PSVT)환자위대조조,대매례환자균매일다차측량체온병동시행심전도검사,채용Bazett공식계산QTc,장체온화QTc관계회제성산점도병진행상관성검험.결과 8례BrS환자균위남성,평균년령(47.38±15.05)세,균유훈궐사,유가족졸사사(1례),림상기록실성심동과속(VT)혹심실전동(VF)4례,전생리검사(EPS)유발VT혹VF 5례.8례PSVT환자(남녀비례위4∶4),평균년령(43.75±10.47)세,방실결절반성심동과속5례,방실절반성심동과속3례.BrS조체온여QTc지간구유상관성,상관계수0.6(P<0.05),이대조조량자지간무상관성(P>0.05).결론 BrS환자체온여QTc정정상관,수착체온적승고,QTc정승고추세,용역발생실성심률실상.
Objective The aim of this study was to investigate the correlation of body temperature with QTc in patients with Brugada syndrome(BrS),and also explore its clinical implication.Methods The patients with BrS admitted at our institution from May 2008 to May 2013 were regard as the experimental group(BrS group),and age and sex-matched patients with paroxysmal supraventricular tachycardia(PSVT) were enrolled into the control group.Body temperature of each patient was multiple sites measured daily.Electrocardiogram examination was consisted with body temperature measurement.Bazett formula was used to calculate QTc.We drew the scatter diagram and did the correlation analysis for the body temperature and QTc in two groups,respectively.Results Eight patients with BrS were male,mean age (47.38± 15.05)years,all of them had a history of syncope.Of them,one patient had family history of cardiac sudden death,4 patients were documented ventricular tachycardia(VT) or ventricular fibrillation(VF),and 5 patients with VT or VF induced by electrophysiological test (EPS).Eight patients in PSVT group,mean age was (43.75±10.47)years,of them 5 patients with atrioventricular nodal reentrant tachycardia,3 patients with atrioventricular reentrant tachycardia.In BrS group,the body temperature was strong correlation with QTc,r =0.6 (P<0.05).However,there was no correlation between them in the control group(P>0.05).Conclusion There was positive correlation between body temperature and QTc in patients with BrS.With temperature increasing,QTc prolonged,VF/VT was easily induced.