国际医药卫生导报
國際醫藥衛生導報
국제의약위생도보
INTERNATIONAL MEDICINE & HEALTH GUIDANCE NEWS
2015年
2期
171-173
,共3页
NT-proBNP%呼吸衰竭%肺源性心脏病%预后评估
NT-proBNP%呼吸衰竭%肺源性心髒病%預後評估
NT-proBNP%호흡쇠갈%폐원성심장병%예후평고
NT-proBNP%Respiratory failure%Cor pulmonale%Prognostic evaluation
目的 观察NT-proBNP在呼吸衰竭及慢性肺源性心脏病合并呼吸衰竭患者中的水平变化,评价NT-proBNP对呼吸衰竭、呼吸衰竭并慢性肺源性心脏病的严重程度、预后评估的价值.方法 选择2012年1月至2013年12月我科收治的55例呼吸衰竭患者,50例呼吸衰竭并慢性肺心病患者,测定入院时NT-proBNP血清浓度,比较两组患者NT-proBNP数值变化,再次以NT-proBNP 2000 pg/ml为截点,分为两组(A组为浓度高者,B组为浓度低者),观察两组患者住院天数、8个月内不良事件发生数.结果 呼吸衰竭并慢性肺心病患者NT-proBNP水平显著高于呼吸衰竭患者,差异有统计学意义(P＜0.05),NT-proBNP≥2000 pg/ml组8月内不良事件发生率高,差异有统计学意义(P＜0.01).结论 NT-proBNP水平变化对呼吸衰竭、慢性肺源性心脏病诊断及预后有一定的临床评价意义.
目的 觀察NT-proBNP在呼吸衰竭及慢性肺源性心髒病閤併呼吸衰竭患者中的水平變化,評價NT-proBNP對呼吸衰竭、呼吸衰竭併慢性肺源性心髒病的嚴重程度、預後評估的價值.方法 選擇2012年1月至2013年12月我科收治的55例呼吸衰竭患者,50例呼吸衰竭併慢性肺心病患者,測定入院時NT-proBNP血清濃度,比較兩組患者NT-proBNP數值變化,再次以NT-proBNP 2000 pg/ml為截點,分為兩組(A組為濃度高者,B組為濃度低者),觀察兩組患者住院天數、8箇月內不良事件髮生數.結果 呼吸衰竭併慢性肺心病患者NT-proBNP水平顯著高于呼吸衰竭患者,差異有統計學意義(P＜0.05),NT-proBNP≥2000 pg/ml組8月內不良事件髮生率高,差異有統計學意義(P＜0.01).結論 NT-proBNP水平變化對呼吸衰竭、慢性肺源性心髒病診斷及預後有一定的臨床評價意義.
목적 관찰NT-proBNP재호흡쇠갈급만성폐원성심장병합병호흡쇠갈환자중적수평변화,평개NT-proBNP대호흡쇠갈、호흡쇠갈병만성폐원성심장병적엄중정도、예후평고적개치.방법 선택2012년1월지2013년12월아과수치적55례호흡쇠갈환자,50례호흡쇠갈병만성폐심병환자,측정입원시NT-proBNP혈청농도,비교량조환자NT-proBNP수치변화,재차이NT-proBNP 2000 pg/ml위절점,분위량조(A조위농도고자,B조위농도저자),관찰량조환자주원천수、8개월내불량사건발생수.결과 호흡쇠갈병만성폐심병환자NT-proBNP수평현저고우호흡쇠갈환자,차이유통계학의의(P＜0.05),NT-proBNP≥2000 pg/ml조8월내불량사건발생솔고,차이유통계학의의(P＜0.01).결론 NT-proBNP수평변화대호흡쇠갈、만성폐원성심장병진단급예후유일정적림상평개의의.
Objective To observe serum NT-proBNP level in patients with respiratory failure (RF) and patients with RF combined with chronic cor pulmonale,investigate the value of NT-proBNP in evaluation of severity and prognosis in RF and RF combined with chronic cor pulmonale.Methods 55 cases of RF and 50 cases of RF combined with chronic cor pulmonale in our department from Jan.2012 to Dec.2013 were selected.Tested and compared serum NT-proBNP concentration in two groups.All patients were divided into two groups according to serum NT-proBNP concentration (group A:serum NT-proBNP concentration ≥ 2000 pg/ml; group B:serum NT-proBNP concentration ＜ 2000 pg/ml).Hospitalization day and the incidence of adverse events within 8 months were compared between two groups.Results Serum NT-proBNP concentration in patients with RF combined with chronic cor pulmonale was significantly higher than that in patients with RF (P ＜ 0.05).The rate of adverse events within 8 months in group A was significantly higher than that in group B (P ＜ 0.01).Conclusion Serum NT-proBNP concentration is helpful for diagnosis and prognosis evaluation for RF and chronic cor pulmonale.
