CAJ | 학술논문

目的探讨急性脑梗死(ACI)中医证型与同型半胱氨酸(HCY)之间的关系.方法对171例ACI患者进行中医辨证分型,分为痰火阻络证、痰热腑实证、痰湿蒙神证、气虚血瘀证、阴虚风动证5组,分别测定脑梗死患者血浆HCY水平,并分别进行组间比较,对比各证型HCY的情况.结果各证型HCY异常情况的比较有统计学差异.痰热腑实型、气虚血瘀型与其他证型比较HCY水平差异有统计学意义(P＜0.05),痰热腑实型、气虚血瘀型HCY水平两型之间差异无统计学意义(P＞0.05).结论血浆HCY水平可作为急性脑梗死中医辨证分型的客观指标之一,因HCY是脑梗死的独立危险因素,因此痰热腑实型、气虚血瘀型是脑梗死的危险证型.
목적 탐토급성뇌경사(ACI)중의증형여동형반광안산(HCY)지간적관계.방법 대171례ACI환자진행중의변증분형,분위담화조락증、담열부실증、담습몽신증、기허혈어증、음허풍동증5조,분별측정뇌경사환자혈장HCY수평,병분별진행조간비교,대비각증형HCY적정황.결과 각증형HCY이상정황적비교유통계학차이.담열부실형、기허혈어형여기타증형비교HCY수평차이유통계학의의(P＜0.05),담열부실형、기허혈어형HCY수평량형지간차이무통계학의의(P＞0.05).결론 혈장HCY수평가작위급성뇌경사중의변증분형적객관지표지일,인HCY시뇌경사적독립위험인소,인차담열부실형、기허혈어형시뇌경사적위험증형.
Objective To study the relationship between acute cerebral infarction (ACI) TCM syndrome-types and homocysteine (HCY).Methods 171 cases of ACI were divided into 5 groups according to the standards of TCM syndrome-types,phlegm heat blocking collaterals syndrome,phlegmheat-bowel excess syndrome,phlegmy wet God card syndrome,Qi-deficiency and blood-stasis syndrome and Yin-deficiency and wind-move syndrome.HCY was determined respectively and then compared.Results There were statistically significant differences in HCY between phlegm-heat-bowel excess syndrome,Qi-deficiency and blood-stasis syndrome group and other groups (P ＜ 0.05),no statistically significant difference in HCY between phlegm-heat-bowel excess syndrome group and Qi-deficiency and blood-stasis syndrome group (P ＞ 0.05).Conclusion HCY can be used as an objective indicator of ACI TCM syndrome-types.HCY is an independent risk factor for ACI,so phlegm-heat-bowel excess syndrome and Qi-deficiency and blood-stasis syndrome are dangerous syndrome-types for ACI.