中华全科医师杂志
中華全科醫師雜誌
중화전과의사잡지
CHINESE JOURNAL OF GENERAL PRACTITIONERS
2015年
2期
139-142
,共4页
王永红%徐春平%沈晓峰%李海红
王永紅%徐春平%瀋曉峰%李海紅
왕영홍%서춘평%침효봉%리해홍
肝炎病毒,乙型%血清流行病学研究
肝炎病毒,乙型%血清流行病學研究
간염병독,을형%혈청류행병학연구
Hepatitis B virus%Seroepidemologic studies
回顾分析我校2007-2012级新生入学体检时HBV血清5项指标的检测结果.共体检新生10 827人,其中2007、2008和2009级新生5 021人,HBsAg阳性率为4.5％(226/5 021),各级HBsAg阳性率分别为4.8％、4.8％和4.0％,差异无统计学意义;单项表面抗体(HBsAb)阳性率为34.8％,各级分别为37.4％、29.0％和37.9％,2008级低于2007和2009级(均P＜0.01);HBV 5项均阴性率58.3％,各级分别为55.4％、63.9％和55.8％,2008级高于2007和2009级(均P＜0.01);HBsAg阳性者中,HBsAg、HBeAg和HBcAb阳性者占34.5％,HBsAg、HBeAb和HBcAb阳性者占44.2％;男生HBsAg阳性率高于女性(5.1％与3.2％,P＜0.01).2010、2011和2012级新生5 806人中,血ALT ＞40 U/L者522人(9.0％),其中HBsAg阳性者12人(2.3％),单项HBsAb阳性者213人(40.8％),HBV 5项均阴性288人(55.2％).提示,一半以上新生无乙肝保护性抗体,人群免疫水平低,应加强校园乙型肝炎相关知识宣传力度,加强监控,提高乙肝疫苗预防及强化接种率.
迴顧分析我校2007-2012級新生入學體檢時HBV血清5項指標的檢測結果.共體檢新生10 827人,其中2007、2008和2009級新生5 021人,HBsAg暘性率為4.5％(226/5 021),各級HBsAg暘性率分彆為4.8％、4.8％和4.0％,差異無統計學意義;單項錶麵抗體(HBsAb)暘性率為34.8％,各級分彆為37.4％、29.0％和37.9％,2008級低于2007和2009級(均P＜0.01);HBV 5項均陰性率58.3％,各級分彆為55.4％、63.9％和55.8％,2008級高于2007和2009級(均P＜0.01);HBsAg暘性者中,HBsAg、HBeAg和HBcAb暘性者佔34.5％,HBsAg、HBeAb和HBcAb暘性者佔44.2％;男生HBsAg暘性率高于女性(5.1％與3.2％,P＜0.01).2010、2011和2012級新生5 806人中,血ALT ＞40 U/L者522人(9.0％),其中HBsAg暘性者12人(2.3％),單項HBsAb暘性者213人(40.8％),HBV 5項均陰性288人(55.2％).提示,一半以上新生無乙肝保護性抗體,人群免疫水平低,應加彊校園乙型肝炎相關知識宣傳力度,加彊鑑控,提高乙肝疫苗預防及彊化接種率.
회고분석아교2007-2012급신생입학체검시HBV혈청5항지표적검측결과.공체검신생10 827인,기중2007、2008화2009급신생5 021인,HBsAg양성솔위4.5％(226/5 021),각급HBsAg양성솔분별위4.8％、4.8％화4.0％,차이무통계학의의;단항표면항체(HBsAb)양성솔위34.8％,각급분별위37.4％、29.0％화37.9％,2008급저우2007화2009급(균P＜0.01);HBV 5항균음성솔58.3％,각급분별위55.4％、63.9％화55.8％,2008급고우2007화2009급(균P＜0.01);HBsAg양성자중,HBsAg、HBeAg화HBcAb양성자점34.5％,HBsAg、HBeAb화HBcAb양성자점44.2％;남생HBsAg양성솔고우녀성(5.1％여3.2％,P＜0.01).2010、2011화2012급신생5 806인중,혈ALT ＞40 U/L자522인(9.0％),기중HBsAg양성자12인(2.3％),단항HBsAb양성자213인(40.8％),HBV 5항균음성288인(55.2％).제시,일반이상신생무을간보호성항체,인군면역수평저,응가강교완을형간염상관지식선전력도,가강감공,제고을간역묘예방급강화접충솔.
To analyze the test results of five serum markers of hepatitis B virus (HBV) among university freshmen from 2007 to 2012.Among a total of 10 827 freshmen,there were 5 021 freshmen from 2007 to 2009 with all five serum markers.The overall ratio of HBsAg positive was 4.5％,4.8％,4.8％ and 4.0％ for each year.And it had no statistically significant difference.The overall ratio of single-HBsAb positive was 34.8％,37.4％,29.0％ and 37.9％ for each year and the figure of 2008 was lower than those of 2007 and 2009 (P ＜ 0.01).The overall ratio of five markers all negative were 58.3％,55.4％,63.9％ and 55.8％ for each year and the figure of 2008 was higher than those of 2007 and 2009 (P ＜ 0.01).And 34.5％ of HBsAg positive freshmen were HBsAg(+),HBeAg (+),HBcAb (+) and 44.2％ HBsAg(+),HBeAb(+),HBcAb(+).The prevalence ratio of HBsAg for males was higher than that for females (5.1％ vs.3.2％,P ＜0.01).Among 5 806 freshmen tested during 2010-2012,522(9.0％) had a serum level of alanine transaminase (ALT) ＞ 40 U/L,including HBsAg positive (n =12),single anti-HBs positive (n =213) and five negatives (n =288).Approximate 50％ university freshmen have no anti-HBs indicating a low level of immunity.And the students should acquire the knowledge of hepatitis B,improve the ratio of vaccination,strengthen the monitoring and prevent its spread through concerted measures.
