CAJ | 학술논문

目的分析总结我国心脏与其他实体器官联合移植的现状.方法对中国心脏移植科学注册中心的数据进行回顾性分析.结果 2003年12月至2014年10月,我国共有8家医院的移植中心上报16例心肺联合移植,采用经典法、双腔静脉法或全心法心脏移植,体外循环时间(281.5±76.2)min,升主动脉阻断时间(164.2±81.9)min.术后院内死亡5例,11例存活出院,出院后死亡5例,其存活时间分别为1.5年2例,2年、3年和5年各1例;6例仍存活,存活时间分别＞2年者2例,＞3年者2例,＞8年者1例,＞11年者1例.2001年4月至2014年6月,我国共有7家医院的移植中心上报8例心肾联合移植,采用经典法或双腔静脉法心脏移植,体外循环时间(138.2±71.1)min,升主动脉阻断时间(67.0±44.6)min.供肾移植于髂窝.术后院内死亡4例,4例存活出院,出院后死亡1例,其存活时间为2年,另3例至今分别存活＞1年、＞2年和＞14年.心肝和心肝肾联合移植各1例,手术时间分别为2011年11月和2007年9月,心肝联合移植者因多器官功能衰竭院内死亡;心肝肾联合移植的受者存活出院,出院后1.5年死亡.结论我国心脏与其他实体器官联合移植的例数不多,但单就受者的存活率来看,心肺联合移植的效果尚令人满意,除此之外的联合移植还有待进一步加强.
목적 분석총결아국심장여기타실체기관연합이식적현상.방법 대중국심장이식과학주책중심적수거진행회고성분석.결과 2003년12월지2014년10월,아국공유8가의원적이식중심상보16례심폐연합이식,채용경전법、쌍강정맥법혹전심법심장이식,체외순배시간(281.5±76.2)min,승주동맥조단시간(164.2±81.9)min.술후원내사망5례,11례존활출원,출원후사망5례,기존활시간분별위1.5년2례,2년、3년화5년각1례;6례잉존활,존활시간분별＞2년자2례,＞3년자2례,＞8년자1례,＞11년자1례.2001년4월지2014년6월,아국공유7가의원적이식중심상보8례심신연합이식,채용경전법혹쌍강정맥법심장이식,체외순배시간(138.2±71.1)min,승주동맥조단시간(67.0±44.6)min.공신이식우가와.술후원내사망4례,4례존활출원,출원후사망1례,기존활시간위2년,령3례지금분별존활＞1년、＞2년화＞14년.심간화심간신연합이식각1례,수술시간분별위2011년11월화2007년9월,심간연합이식자인다기관공능쇠갈원내사망;심간신연합이식적수자존활출원,출원후1.5년사망.결론 아국심장여기타실체기관연합이식적례수불다,단단취수자적존활솔래간,심폐연합이식적효과상령인만의,제차지외적연합이식환유대진일보가강.
Objective To analyze the current status of heart combined transplantation in Chinese mainland.Method Retrospectively described and analyzed the data of China heart transplant Registry.Result By standard technique,bicaval technique or total orthotopic cardiac transplant technique,16 recipients underwent heart-lung combined transplantation(HLT) from December 2003 to October 2012 in 8 transplant centers,with the Cardiopulmonary bypass time of 281.5 ± 76.2 min and the ascending aortic cross-clamping time of 164.2 ± 81.9 min.5 recipients died intra-hospital and 11 discharged from hospital.In the recipients discharged,5 died(2 recipients survived for 1.5 years,the other 3 died in the 2nd,3rd and 5th year) and 6 still survive(2 recipients survive for＞2 years,2 survive for＞3years,1 survive for＞8 years and 1 survive for＞11 years).By standard technique and bicaval technique,8 recipients underwent heart-kidney combined transplantation(HKL) from April 2001 to June 2014 in 7 transplant centers,with the Cardiopulmonary bypass time of 138.2 ± 71.1 min and the ascending aortic cross-clamping time of 67.0 ± 44.6 min.All donor kidneys implanted in iliac fossa.4 recipients died intra-hospital and the other 4 discharged from hospital.In the recipients discharged,1 died in 2th year and the other 3 still survive currentlyfor＞1,2 and 14 years.1 recipient underwent heart-liver combined transplantation in November 2011 and died intra-hospital from multiple organ failure.1 recipient underwent heart-liver-kidney combined transplantation in September 2007 and survived for 1.5 years.Conclusion There is still small quantity of heart combined transplant cases in Chinese mainland.The survival of heart-lung transplantation seems relatively satisfactory and the other kinds of heart combined transplantation still need to develop